Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shyam Goverdhana"'
Autor:
Weidong Xiong, Carlos Barcia, James F. Curtin, Pedro R. Lowenstein, Diana S. Greengold, Jeffrey M. Zirger, Shyam Goverdhana, Gwendalyn D. King, Marianela Candolfi, Sonali Mondkar, Mariana Puntel, Jiang Hu, E. B. Soffer, Sandra A. Sciascia, Maria G. Castro
Publikováno v:
Molecular Therapy. 12(2):189-211
Gene therapy aims to revert diseased phenotypes by the use of both viral and nonviral gene delivery systems. Substantial progress has been made in making gene transfer vehicles more efficient, less toxic, and nonimmunogenic and in allowing long-term
Autor:
Carlos Barcia, Chunyan Liu, Gwendalyn D. King, James F. Curtin, Jeffrey M. Zirger, Mariana Puntel, Pedro R. Lowenstein, Maria G. Castro, Shyam Goverdhana, Weidong Xiong, Sumia Ali
Publikováno v:
Molecular Therapy. 10:1071-1084
Glioblastoma multiforme is an intracranial tumor that has very poor prognosis. Patients usually succumb to their disease 6 to 12 months after they are diagnosed despite very aggressive treatment modalities. We tested the efficacy of a potent differen
Publikováno v:
The Endocrinologist. 13:351-357
Pituitary tumors are normally benign, highly differentiated, and slow-growing neoplasms. Despite this, in almost half of the cases, there will be evidence of local invasion into the surrounding structures. Despite their benign growth characteristics
Autor:
Christopher J. Wheeler, Akanksha Panwar, Hongqiang Wang, Emmanuel Jouanneau, Armen Mardiros, Lucia Veiga, Xiao-xue Zhang, Keith L. Black, Ryan Cordner, Dwain K. Irvin, Shyam Goverdhana, Yuying Zhai, Ashley Gragg, Mandana Zandian
Publikováno v:
Cancer immunology, immunotherapy : CII. 63(9)
Cancer vaccines reproducibly cure laboratory animals and reveal encouraging trends in brain tumor (glioma) patients. Identifying parameters governing beneficial vaccine-induced responses may lead to the improvement of glioma immunotherapies. CD103(+)
Publikováno v:
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
Gene therapy for neurological diseases faces many challenges from the anatomy of the brain, that is, its physical encasing by the cranical cavity, and its separation from the bloodstream by the blood brain barrier. This has forced the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ac512f0d71b5b4cfe599b99e029593
https://doi.org/10.1002/047001153x.g107201
https://doi.org/10.1002/047001153x.g107201
Autor:
Shyam Goverdhana, Pedro R. Lowenstein, Weidong Xiong, Moneeb Ehtesham, Xiangpeng Yuan, John S. Yu, Maria G. Castro, Nelson Jovel, Diana S. Greengold, Jinwei Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f4058b6b2f021c8d2f3d03d0a3ee85a
https://doi.org/10.1159/000084481
https://doi.org/10.1159/000084481
Autor:
Pedro R, Lowenstein, Donata, Suwelack, Jinwei, Hu, Xianpeng, Yuan, Maximiliano, Jimenez-Dalmaroni, Shyam, Goverdhana, Maria G, Castro
Publikováno v:
International review of neurobiology. 55
Autor:
Xiangpeng Yuan, Jinwei Hu, Nelson Jovel, Pedro R. Lowenstein, Maria G. Castro, Shyam Goverdhana
Publikováno v:
Frontiers in neuroendocrinology. 24(1)
Gene therapy, which entails the use of nucleic acids as drugs, is a new approach to treat disease. Gene therapy has been successfully implemented in several preclinical animal models, including several paradigms of experimental pituitary tumors. In s
Autor:
Donata Suwelack, Maria G. Castro, Pedro R. Lowenstein, Maximiliano J. Jiménez-Dalmaroni, Xianpeng Yuan, Shyam Goverdhana, Jinwei Hu
Publikováno v:
International Review of Neurobiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf750a352167b7dd462f092aa6a1213
https://doi.org/10.1016/s0074-7742(03)01001-8
https://doi.org/10.1016/s0074-7742(03)01001-8
Autor:
Maria G. Castro, Shyam Goverdhana, Diana S. Greengold, James F. Curtin, Weidong Xiong, Eric Soffer, Pedro R. Lowenstein
Publikováno v:
Molecular Therapy. 9:S299-S300
Introduction: Gene therapy is not only a powerful but also notably an efficient therapeutic intervention because of the feasibility of gene regulation by exploiting novel tetracycline based transcriptional inducible gene expression systems. Tet-on re