Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shyam, Basak"'
Publikováno v:
ARKIVOC, Vol 2018, Iss 3, Pp 257-269 (2018)
Externí odkaz:
https://doaj.org/article/456632fee7c8440384f835338f5aaacd
Publikováno v:
Organic & Biomolecular Chemistry. 20:1444-1452
Photo-cross-linking experiments demonstrated direct interactions of the drug thioacetazone with its target enzymes, namely both the dehydratases HadAB and HadBC via the monooxygenase EthA in Mycobacterium tuberculosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2efb3c332d7256c5031fda5fa33f2f
https://doi.org/10.1039/d1ob02080c
https://doi.org/10.1039/d1ob02080c
Publikováno v:
The Journal of Organic Chemistry. 84:2911-2921
Inducing high regioselectivity in nucleophilic addition to p-benzynes, first reported by Perrin and O'Connor et al. ( J. Am. Chem. Soc. 2007 , 129 , 4795 - 4799 ) has been a challenge as the reaction involves a very fast barrier-less addition of nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32a6ed4303e2314fa228021d1a0f5de
https://doi.org/10.1021/acs.joc.9b00060
https://doi.org/10.1021/acs.joc.9b00060
Autor:
Betty A. Kustiana, Shyam Basak, Laura Winfrey, Alexander P. Pulis, Louis C. Morrill, Rebecca L. Melen
The manipulation of amino C-H bonds has garnered significant interest from the synthetic community due to its inherently high atom, step and redox economy. This Tutorial Review summarises the ability of boranes to mediate hydride abstraction from α-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0494f40b49f7142c169710a7520e1aad
https://orca.cardiff.ac.uk/id/eprint/138468/1/d0cs00531b.pdf
https://orca.cardiff.ac.uk/id/eprint/138468/1/d0cs00531b.pdf
Autor:
Louis C. Morrill, Ana Alvarez-Montoya, Rebecca L. Melen, Alexander P. Pulis, Laura Winfrey, Shyam Basak
The direct C3 alkylation of indoles and oxindoles is a challenging transformation, and only a few direct methods exist. Utilizing the underexplored ability of triaryl boranes to mediate the heterolytic cleavage of α-nitrogen C–H bonds in amines, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3edab732e4ed8f1963447e607a473b
https://orca.cardiff.ac.uk/id/eprint/131072/7/acscatal.0c01141.pdf
https://orca.cardiff.ac.uk/id/eprint/131072/7/acscatal.0c01141.pdf
Autor:
Shyam, Basak, Ana, Alvarez-Montoya, Laura, Winfrey, Rebecca L, Melen, Louis C, Morrill, Alexander P, Pulis
Publikováno v:
ACS Catalysis
The direct C3 alkylation of indoles and oxindoles is a challenging transformation, and only a few direct methods exist. Utilizing the underexplored ability of triaryl boranes to mediate the heterolytic cleavage of α-nitrogen C–H bonds in amines, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de9e37cfe5f4f41cc5a7e2735e32765a
https://pubmed.ncbi.nlm.nih.gov/32596025
https://pubmed.ncbi.nlm.nih.gov/32596025
Publikováno v:
The Journal of Organic Chemistry. 83:7730-7740
The regioselectivity in addition of nucleophiles to the p-benzyne intermediates derived from unsymmetrical aza-substituted enediynes via Bergman cyclization was studied. Computational studies [using UB3LYP/6-31G(d,p) level of theory] suggest that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7919325e8d1fa64ba6132b99947b9b09
https://doi.org/10.1021/acs.joc.8b00624
https://doi.org/10.1021/acs.joc.8b00624
Publikováno v:
ARKIVOC, Vol 2018, Iss 3, Pp 257-269 (2018)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1cd9c6f712a8790bb493a0d852d713
https://doi.org/10.24820/ark.5550190.p009.921
https://doi.org/10.24820/ark.5550190.p009.921
Publikováno v:
Tetrahedron. 74:96-103
K-259-2, a unique calmodulin antagonist, is an allyl chain containing anthraquinone natural product. A regiospecific synthetic approach towards K-259-2 is herein represented. The study also showcases a protocol for synthesizing heavily substituted br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f320c0d5c191d74f679e18a58b1f5e
https://doi.org/10.1016/j.tet.2017.11.037
https://doi.org/10.1016/j.tet.2017.11.037
Autor:
Shyam Basak, Dipakranjan Mal
Publikováno v:
The Journal of Organic Chemistry. 82:11035-11051
Hexa-2,5-dienoates, susceptible to isomerization by acids and bases, are suitable for the [4+2] anionic annulation to give 3-(2-alkenyl)naphthoates in regiospecific manner. When combined with intramolecular carbonyl-ene reaction (ICE), the accessibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1addbe63eb82e83338cbb7b7694e618e
https://doi.org/10.1021/acs.joc.7b01987
https://doi.org/10.1021/acs.joc.7b01987