Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shweta Umar"'
We have designed and synthesized amide derivatives of substituted 3-methyl-benzofuran-2-carboxylic acid with aryl sulfonamide piperazines, aryl hydrazides and aryl hydrazines. All the synthesized compounds were screened for their anticancer activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffef23c02b820433c8cc15078fc97c0
Publikováno v:
Synthetic Communications. 48:2877-2887
Herein, we have designed various benzisoxazole acetamide derivatives with and without glycine spacer as DPP-IV inhibitors. Compounds 9a–d and 11a–e were synthesized and screened for their in vitro DPP-IV inhibition. Compounds 11a and 11c showed m
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 34
New chemotherapeutic agents with minimum side effects are indispensable to treat non-small-cell lung cancer (NSCLC) since the mortality rate of patients suffering from NSCLC remains high despite receiving conventional medication. In our previous stud
Flavonoids are widely occurring polyphenols of plant origin and well explored in the field of pharmacological activities. Recent studies showed this scaffold to be more dynamic as fluorescent probe. Very rare reports are there in literature on flavon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0ee6a6321c9c751a6a71a21e719749
Publikováno v:
Journal of Heterocyclic Chemistry. 54:2501-2510
A series of substituted aminomethylbenzocoumarin derivatives 8a–i have been synthesized, characterized, and structure of compound 8g was confirmed by X-ray single crystal analysis. All the synthesized compounds were tested for their anticancer acti
Publikováno v:
ChemistrySelect. 2:147-153
We have designed and synthesized novel 7-substituted-3-acetyl-benzopyrones 9 a-9 g and ethyl 7-substituted-3-carboxylate-benzopyrones 10 a-10 d and screened for anticancer activity using MTT assay. Most of the tested compounds have shown very good ac
Publikováno v:
Chemical biologydrug design. 92(1)
Herein we report design, synthesis, and anticancer activity of compounds 6a-h and 11a-j. Compounds 6a-f were designed based on 3-aminomethyl pyridine attached to different acetamide derivatives and in compounds 6g-h it was attached to coumarin moiety