Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shweta Rane"'
Publikováno v:
Cellular Signalling. 22:1054-1062
We have recently reported that downregulation of miR-199a-5p is necessary and sufficient for inducing upregulation of its targets, including hypoxia-inducible factor-1 alpha (Hif-1 alpha) and Sirt1, during hypoxia preconditioning (HPC). Conversely, o
Autor:
Dorothy E. Vatner, Maha Abdellatif, Stephen F. Vatner, Ashwani Malhotra, Shweta Rane, Himanshu Vashistha, Danish Sayed, Minzhen He, Junichi Sadoshima
Publikováno v:
Circulation Research. 104:879-886
MicroRNAs are posttranscriptional gene regulators that are differentially expressed during various diseases and have been implicated in the underlying pathogenesis. We report here that miR-199a is acutely downregulated in cardiac myocytes on a declin
Publikováno v:
Journal of Cardiovascular Translational Research. 2:100-107
MicroRNAs (miRNAs) are recently discovered posttranscriptional regulators of gene expression that have become a cause célèbre. There are currently more than 600 miRNAs identified in humans that are estimated to regulate about one third of all messe
Autor:
Dorothy E. Vatner, Shweta Rane, Danish Sayed, Ashwani Malhotra, Minzhen He, Lin Yan, Ieng-Yi Chen, Maha Abdellatif, Himanshu Vashistha, Jacqueline Lypowy
Publikováno v:
Molecular Biology of the Cell. 19:3272-3282
The posttranscriptional regulator, microRNA-21 (miR-21), is up-regulated in many forms of cancer, as well as during cardiac hypertrophic growth. To understand its role, we overexpressed it in cardiocytes where it revealed a unique type of cell-to-cel
Publikováno v:
Circulation. 118
MicroRNAs (miRNA) are touted to be fundamental posttranscriptional regulators of gene expression. They are differentially regulated during health and disease states with a major impact on cellular functions. We found that miR-199a is upregulated (4.8
Autor:
Danish Sayed, Shweta Rane, Leng-Yi Chen, Minzhen He, Jacqueline Lypowy, Stefan Engelhardt, Lin Yan, Dorothy Vatner, Junichi Sadoshima, Maha Abdellatif
Publikováno v:
Circulation. 116
MicroRNA (miRNA) are ~22 ribonucleotides-long, with a potential to recognize multiple mRNA targets guided by sequence complimentarity. This class of molecules is functionally versatile, with the capacity to specifically inhibit translation, as well a