Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shweta Mandrekar"'
Publikováno v:
ASN Neuro, Vol 5 (2013)
Traumatic injury or disease of the spinal cord and brain elicits multiple cellular and biochemical reactions that together cause or are associated with neuropathology. Specifically, injury or disease elicits acute infiltration and activation of immun
Externí odkaz:
https://doaj.org/article/c5230484558546c09727ee7f6e76ee5a
Autor:
Zhen Guan, Andrew D. Gaudet, Xiaokui Mo, David R Sweet, Shweta Mandrekar-Colucci, Phillip G. Popovich, Philipp J Schmitt, Jodie C. E. Hall, Xinyang Xu, Mireia Guerau-de-Arellano
Publikováno v:
Journal of Neuroscience. 36:8516-8532
Axon regeneration after spinal cord injury (SCI) fails due to neuron-intrinsic mechanisms and extracellular barriers including inflammation. microRNA (miR)-155–5p is a small, noncoding RNA that negatively regulates mRNA translation. In macrophages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616cf7dcff1170723c36e3caf9a3de02
https://doi.org/10.1523/jneurosci.0735-16.2016
https://doi.org/10.1523/jneurosci.0735-16.2016
Autor:
Yi Zhang, Todd Shawler, Alexander G. Rabchevsky, Nicole D. Powell, Caroline C. Whitacre, Mark S. Nash, Jonathan Wells, Anna Bratasz, Brenda F. Reader, Shweta Mandrekar-Colucci, John F. Sheridan, Zachary M. Weil, Zhen Guan, Kun Huang, Phillip G. Popovich
Publikováno v:
Journal of Neuroscience. 33:12970-12981
Autonomic dysreflexia (AD), a potentially dangerous complication of high-level spinal cord injury (SCI) characterized by exaggerated activation of spinal autonomic (sympathetic) reflexes, can cause pulmonary embolism, stroke, and, in severe cases, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd9a1bc4f5bc5eadf85c8ec8bc5c448
https://doi.org/10.1523/jneurosci.1974-13.2013
https://doi.org/10.1523/jneurosci.1974-13.2013
Publikováno v:
Journal of Neuroscience. 32:10117-10128
Alzheimer's disease is associated with a disruption of amyloid β (Aβ) homeostasis, resulting in the accumulation and subsequent deposition of Aβ peptides within the brain. The peroxisome proliferator-activated receptor-γ (PPARγ) is a ligand-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c92cc654d578e02d0c03dacac37b92
https://doi.org/10.1523/jneurosci.5268-11.2012
https://doi.org/10.1523/jneurosci.5268-11.2012
Publikováno v:
Expert Opinion on Therapeutic Targets. 15:1085-1097
Alzheimer's disease (AD) is characterized by the accumulation and extensive deposition of amyloid β (Aβ) in the parenchyma of the brain. This accumulation of amyloid is associated with perturbations in synaptic function, impairments in energy metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af8c78171a8bccb765e5f82bc694251
https://doi.org/10.1517/14728222.2011.594043
https://doi.org/10.1517/14728222.2011.594043
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 9:156-167
One hundred and fifty years have elapsed since the original discovery of the microglial cell by Virchow. While this cell type has been well studied, the role of microglia in the pathology of many central nervous system diseases still remains enigmati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81bfb6b2f24fc6f408113fd884568e9
https://doi.org/10.2174/187152710791012071
https://doi.org/10.2174/187152710791012071
Publikováno v:
Neurotherapeutics. 5:481-489
Alzheimer's disease (AD) is characterized by the deposition of beta-amyloid within the brain parenchyma and is accompanied by the impairment of neuronal metabolism and function, leading to extensive neuronal loss. The disease involves the perturbatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc72f1fbbdd3b76388eb6c382871311a
https://doi.org/10.1016/j.nurt.2008.05.003
https://doi.org/10.1016/j.nurt.2008.05.003
Autor:
Noam Zelcer, Timothy M. Willson, C. Y. Daniel Lee, Jill C. Richardson, Shweta Mandrekar, David M. Holtzman, Jon L. Collins, Jonathan D. Smith, Qingguang Jiang, Gary E. Landreth, David Riddell, Paige E. Cramer, Karen Mann, Peter Tontonoz, Brandy L. Wilkinson, Bruce T. Lamb, Thomas A. Comery
Publikováno v:
Neuron, 58(5), 681-693. Cell Press
Apolipoprotein E is associated with age-related risk for Alzheimer’s disease and plays critical roles in Aβ homeostasis. We report that ApoE plays a previously unappreciated role in facilitating the proteolytic clearance of soluble Aβ from the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f090b04173c3ef71059dfec8aea90212
Publikováno v:
ASN NEURO
ASN Neuro, Vol 5 (2013)
ASN Neuro, Vol 5 (2013)
Traumatic injury or disease of the spinal cord and brain elicits multiple cellular and biochemical reactions that together cause or are associated with neuropathology. Specifically, injury or disease elicits acute infiltration and activation of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3ae189f75be96021cb367b1e0ad81a
http://europepmc.org/articles/PMC3866683
http://europepmc.org/articles/PMC3866683
Autor:
David M. Holtzman, Qingguang Jiang, Jessica Koenigsknecht-Talboo, Shweta Mandrekar, Gary E. Landreth, C. Y. Daniel Lee
Alzheimer's disease is characterized by the progressive deposition of β-amyloid (Aβ) within the brain parenchyma and its subsequent accumulation into senile plaques. Pathogenesis of the disease is associated with perturbations in Aβ homeostasis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94216e611ce06dc01d3a7380acf8e0c
https://europepmc.org/articles/PMC3034143/
https://europepmc.org/articles/PMC3034143/
