Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shweta, Kailasan"'
Autor:
Mario Mietzsch, Shweta Kailasan, Antonette Bennett, Paul Chipman, Bentley Fane, Juha T. Huiskonen, Ian N. Clarke, Robert McKenna
Publikováno v:
Viruses, Vol 16, Iss 7, p 1103 (2024)
Spiroplasma virus 4 (SpV4) is a bacteriophage of the Microviridae, which packages circular ssDNA within non-enveloped T = 1 icosahedral capsids. It infects spiroplasmas, which are known pathogens of honeybees. Here, the structure of the SpV4 virion i
Externí odkaz:
https://doaj.org/article/d837cfe946374f07a31dec158ee1e2b4
Autor:
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikari, Gaya K. Amarasinghe, Michael L. Gross, M. Javad Aman
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S. aureus-specific vaccines and monoclonal antibodies (mAbs) have failed in clinical trials due to the mult
Externí odkaz:
https://doaj.org/article/536d0a35d34246f88a85754222c857ae
Autor:
Tom Z. Yuan, Pankaj Garg, Linya Wang, Jordan R. Willis, Eric Kwan, Ana G Lujan Hernandez, Emily Tuscano, Emily N. Sever, Erica Keane, Cinque Soto, Eric M. Mucker, Mallorie E. Fouch, Edgar Davidson, Benjamin J. Doranz, Shweta Kailasan, M. Javad Aman, Haoyang Li, Jay W. Hooper, Erica Ollmann Saphire, James E. Crowe, Qiang Liu, Fumiko Axelrod, Aaron K. Sato
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Coronavirus disease 2019 (COVID-19) is an evolving global public health crisis in need of therapeutic options. Passive immunization of monoclonal antibodies (mAbs) represents a promising therapeutic strategy capable of conferring immediate protection
Externí odkaz:
https://doaj.org/article/b6c1901170674ee7807acd867a09110b
Autor:
Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SU
Externí odkaz:
https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f3
Autor:
Logan Banadyga, Wenjun Zhu, Shweta Kailasan, Katie A. Howell, Krzysztof Franaszek, Shihua He, Vinayakumar Siragam, Keding Cheng, Feihu Yan, Estella Moffat, Wenguang Cao, Anders Leung, Carissa Embury-Hyatt, M. Javad Aman, Xiangguo Qiu
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbr
Externí odkaz:
https://doaj.org/article/909040b19d774466a013d0a904fb9c04
Publikováno v:
eLife, Vol 9 (2020)
Key to CRISPR-Cas adaptive immunity is maintaining an ongoing record of invading nucleic acids, a process carried out by the Cas1-Cas2 complex that integrates short segments of foreign genetic material (spacers) into the CRISPR locus. It is hypothesi
Externí odkaz:
https://doaj.org/article/41ac509c24284d8ba48eeb0c2864f484
Autor:
Jennifer Chun Yu, Mario Mietzsch, Amriti Singh, Alberto Jimenez Ybargollin, Shweta Kailasan, Paul Chipman, Nilakshee Bhattacharya, Julia Fakhiri, Dirk Grimm, Amit Kapoor, Indrė Kučinskaitė-Kodzė, Aurelija Žvirblienė, Maria Söderlund-Venermo, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 13, Iss 2, p 330 (2021)
Human bocavirus 1 (HBoV1) has gained attention as a gene delivery vector with its ability to infect polarized human airway epithelia and 5.5 kb genome packaging capacity. Gorilla bocavirus 1 (GBoV1) VP3 shares 86% amino acid sequence identity with HB
Externí odkaz:
https://doaj.org/article/44a5004850054f418bcd4dc8d9e1ce4e
Autor:
Shweta Kailasan, Thomas Kort, Ipsita Mukherjee, Grant C. Liao, Tulasikumari Kanipakala, Nils Williston, Nader Ganjbaksh, Arundhathi Venkatasubramaniam, Frederick W. Holtsberg, Hatice Karauzum, Rajan P. Adhikari, M. Javad Aman
Publikováno v:
Toxins, Vol 11, Iss 6, p 339 (2019)
Staphylococcus aureus (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, S. aureus thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. Whi
Externí odkaz:
https://doaj.org/article/c6f398503f794613afe09b6beeb975f9
Autor:
Shweta, Kailasan, Ravi, Kant, Madeleine, Noonan-Shueh, Tulasikumari, Kanipakala, Grant, Liao, Sergey, Shulenin, Daisy W, Leung, Richard A, Alm, Rajan P, Adhikari, Gaya K, Amarasinghe, Michael L, Gross, M Javad, Aman
Publikováno v:
mAbs. 14(1)
Autor:
Maria Ilyas, Mario Mietzsch, Shweta Kailasan, Elina Väisänen, Mengxiao Luo, Paul Chipman, J. Kennon Smith, Justin Kurian, Duncan Sousa, Robert McKenna, Maria Söderlund-Venermo, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 10, Iss 1, p 22 (2018)
Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, i
Externí odkaz:
https://doaj.org/article/27c333f1ff9c4748bb9a1fd6917baaa1