Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Shuzo Urata"'
Autor:
Shoichi Ashida, Shohei Kojima, Takashi Okura, Fumihiro Kato, Wakako Furuyama, Shuzo Urata, Yusuke Matsumoto
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTParamyxo- and filovirus genomes are equipped with bipartite promoters at their 3' ends to initiate RNA synthesis. The two elements, the primary promoter element 1 (PE1) and the secondary promoter element 2 (PE2), are separated by a spacer reg
Externí odkaz:
https://doaj.org/article/e85cb5e364034fd5b2791d9b47613bce
Autor:
Shuzo Urata, Jun Takouda, Yoshihiro Watanabe, Miako Sakaguchi, Yasuteru Sakurai, Yuki Inahashi, Masato Iwatsuki, Jiro Yasuda, Yoshimasa Tanaka, Kohsuke Takeda
Publikováno v:
Frontiers in Virology, Vol 2 (2023)
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus first identified in China in 2011 and later reported in other Asian countries. Significant efforts have been made to develop anti-SFTSV compounds; however, there are no a
Externí odkaz:
https://doaj.org/article/06aec09f7db946c2aff01e198ed72a0e
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010689 (2022)
Favipiravir is a nucleoside analogue that inhibits the replication and transcription of a broad spectrum of RNA viruses, including pathogenic arenaviruses. In this study, we isolated a favipiravir-resistant mutant of Junin virus (JUNV), which is the
Externí odkaz:
https://doaj.org/article/e7859669d80648b288764465b9f2dbd2
Autor:
Yuri Ushijima, Haruka Abe, Takehiro Ozeki, Georgelin N. Ondo, Marien J.V.M. Mbadinga, Rodrigue Bikangui, Chimène Nze-Nkogue, Etienne F. Akomo-Okoue, Ghislain W.E. Ella, Lilian B.M. Koumba, Branly C.B.B. Nso, Rodrigue Mintsa-Nguema, Patrice Makouloutou-Nzassi, Boris K. Makanga, Fred L.M. Nguelet, Vahid R. Zadeh, Shuzo Urata, Armel V.N. Mbouna, Marguerite Massinga-Loembe, Selidji T. Agnandji, Bertrand Lell, Jiro Yasuda
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 452-459 (2021)
Objectives: Lymphocytic choriomeningitis virus (LCMV), a human pathogenic arenavirus, is distributed worldwide. However, no human cases have been reported in Africa. This study aimed to investigate the current situation and potential risks of LCMV in
Externí odkaz:
https://doaj.org/article/b14ef9c15de048f3ac6d6e4a52adbacb
Publikováno v:
Viruses, Vol 15, Iss 1, p 105 (2022)
Although many arenaviruses cause severe diseases with high fatality rates each year, treatment options are limited to off-label use of ribavirin, and a Food and Drug Administration (FDA)-approved vaccine is not available. To identify novel therapeuti
Externí odkaz:
https://doaj.org/article/aec736c12ff54c4ea91ac54bf3d7f210
Autor:
Yohei Doi, Ken Ishii, Akira Nishizono, Asuka Nanbo, Shuzo Urata, Ichiro Kurane, Jules Carl Celebrado, John Philip Depatillo, Zymar Bandola, Diane E. Griffin, Eun-Chung Park, David McDonald, Kristina Lu, K. Gayle Bernabe, Gray Handley
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 10, Pp - (2021)
Externí odkaz:
https://doaj.org/article/c01d8a238d7b4c49a5a9dd85bb4e8ebe
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidate
Externí odkaz:
https://doaj.org/article/9114de5c6f184bfc909836650c851f1b
Autor:
Toru Takenaga, Zihan Zhang, Yukiko Muramoto, Sarah Katharina Fehling, Ai Hirabayashi, Yuki Takamatsu, Junichi Kajikawa, Sho Miyamoto, Masahiro Nakano, Shuzo Urata, Allison Groseth, Thomas Strecker, Takeshi Noda
Publikováno v:
Viruses, Vol 13, Iss 9, p 1763 (2021)
Lassa virus (LASV)—a member of the family Arenaviridae—causes Lassa fever in humans and is endemic in West Africa. Currently, no approved drugs are available. We screened 2480 small compounds for their potential antiviral activity using pseudotyp
Externí odkaz:
https://doaj.org/article/88db264174c24a2bbd5c6e0ef3cf02bf
Publikováno v:
Viruses, Vol 13, Iss 7, p 1220 (2021)
Arenaviruses and coronaviruses include several human pathogenic viruses, such as Lassa virus, Lymphocytic choriomeningitis virus (LCMV), SARS-CoV, MERS-CoV, and SARS-CoV-2. Although these viruses belong to different virus families, they possess a com
Externí odkaz:
https://doaj.org/article/cc08899f505645938b791d8be85f0d04
Publikováno v:
Viruses, Vol 13, Iss 5, p 869 (2021)
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV). SFTS is mainly prevalent in East Asia. It has a mortality rate of up to 30%, and there is no approved treatm
Externí odkaz:
https://doaj.org/article/06c1da712f7c4337af79c795ea3c3d3f