Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Shuzhen CHEN"'
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract While ferroptosis shows promise in anti-cancer strategy, the molecular mechanisms behind this process remain poorly understood. Our research aims to highlight the regulation of radiotherapy-induced ferroptosis in non-small cell lung cancer (
Externí odkaz:
https://doaj.org/article/c77f67edb58d4e8fb3affc161c9a4a6e
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Objective Non-small cell lung cancer (NSCLC) often exhibits resistance to radiotherapy, posing significant treatment challenges. This study investigates the role of SMAD3 in NSCLC, focusing on its potential in influencing radiosensitivity vi
Externí odkaz:
https://doaj.org/article/7b060b27ed1745cb9e222c2e2a869241
Autor:
Weiguo Song, Hekai Yang, Ying Wang, Shuzhen Chen, Wenda Zhong, Qian Wang, Wenshuo Ding, Guangzhao Xu, Chen Meng, Ying Liang, Zhe‐Sheng Chen, Shuhua Cao, Liuya Wei, Fahui Li
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Multi‐drug resistance (MDR) is a major cause of cancer therapy failure. Photodynamic therapy (PDT) is a promising modality that can circumvent MDR and synergize with chemotherapies, based on the generation of reactive oxygen species (ROS)
Externí odkaz:
https://doaj.org/article/dfe4096d398d4ba78db0668db03a63d9
Publikováno v:
AIMS Microbiology, Vol 9, Iss 4, Pp 780-800 (2023)
There are six major types of CRISPR-Cas systems that provide adaptive immunity in bacteria and archaea against invasive genetic elements. The discovery of CRISPR-Cas systems has revolutionized the field of genetics in many organisms. In the past few
Externí odkaz:
https://doaj.org/article/f127dfa130e24107b107839a9c7ceea8
Autor:
Yuting Song, Ying Wang, Xin Geng, Xianming Wang, Huisi He, Youwen Qian, Yaping Dong, Zhecai Fan, Shuzhen Chen, Wen Wen, Hongyang Wang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The incidence and prevalence of nonalcoholic fatty liver disease related hepatocellular carcinoma (NAFLD-HCC) are rapidly increasing worldwide. This study aimed to identify biomarker genes for prognostic prediction model of NAFLD-
Externí odkaz:
https://doaj.org/article/b10c584643f04296b1092c13e287cfa1
Autor:
Shuzhen Chen, Kaiquan Shi
Publikováno v:
Mathematics, Vol 12, Iss 16, p 2571 (2024)
Data has attributes, and synchronous changes between data and attributes are the basic characteristics of a type of data: under the condition of supplementing (deleting) some attributes, some data elements are deleted (supplemented) from data. The at
Externí odkaz:
https://doaj.org/article/572bb10481804155a7b1f23e50f5fd5b
Autor:
Huisi He, Shuzhen Chen, Zhecai Fan, Yaping Dong, Ying Wang, Shiyao Li, Xiaojuan Sun, Yuting Song, Jinxian Yang, Qiqi Cao, Jie Jiang, Xianming Wang, Wen Wen, Hongyang Wang
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-21 (2023)
Abstract Alpha-fetoprotein (AFP)-secreting hepatocellular carcinoma (HCC), which accounts for ~75% of HCCs, is more aggressive with a worse prognosis than those without AFP production. The mechanism through which the interaction between tumors and th
Externí odkaz:
https://doaj.org/article/079b99242af14cfba0955f4110ec8c69
Autor:
Liping Li, Jia Wang, Xincheng Zhong, Yaoyao Jiang, Gaofeng Pei, Xikang Yang, Kaixiang Zhang, Siqi Shen, Xue Jin, Gaoge Sun, Chaofei Su, Shuzhen Chen, Hang Yin
Publikováno v:
Research, Vol 7 (2024)
The ALPK1 (alpha-kinase 1)-TIFA (TRAF-interacting protein with fork head-associated domain)-TRAF6 signaling pathway plays a pivotal role in regulating inflammatory processes, with TIFA and TRAF6 serving as key molecules in this cascade. Despite its s
Externí odkaz:
https://doaj.org/article/660b604bde894724bc87d5896b2b0e8d
Autor:
Hekai Yang, Fahui Li, Shuzhen Chen, Shanshan Jin, Weiwei Chen, Wen Sun, Liuya Wei, Guangzhao Xu, Weiguo Song, Wenda Zhong
Publikováno v:
Materials & Design, Vol 237, Iss , Pp 112566- (2024)
The excessive production of reactive oxygen species (ROS) can damage the mitochondrial membrane and induce apoptosis, causing endoplasmic reticulum stress and triggering immunogenic cell death. Therefore, the combination of apoptosis and immunogenic
Externí odkaz:
https://doaj.org/article/fd4a3caef874460798227fb24b9d2435
Autor:
Bo Zhao, Yunlong Zhao, Stephanie Adaniya, Yue Fu, Youmi Moon, Justin Heftel, Shuzhen Chen, Hui Xiao, Ning Li
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTDevelopment of novel bispecific antibody (bsAb) platforms offers unprecedented opportunities for a wide variety of therapeutic applications. However, the expression and manufacturing of bsAbs with desired structures can be challenging. Owing
Externí odkaz:
https://doaj.org/article/ac36492a969c474db420c91b1e460110