Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Shuyuan, Yeh"'
Autor:
Dong Chen, Fu-Ju Chou, Yuhchyau Chen, Chi-Ping Huang, Hao Tian, Yaqin Wang, Yuanjie Niu, Bosen You, Shuyuan Yeh, Nianzeng Xing, Chawnshang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-12 (2022)
Abstract Background Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate cancer (PCa). However, we unexpectedly found that RT could also induce the androgen receptor splice v
Externí odkaz:
https://doaj.org/article/4dac9b102b7147abafd5b1e546ebce3b
Autor:
Yang Yang, Jindong Sheng, Shuai Hu, Yun Cui, Jing Xiao, Wei Yu, Jing Peng, Wenke Han, Qun He, Yu Fan, Yuanjie Niu, Jun Lin, Ye Tian, Chawnshang Chang, Shuyuan Yeh, Jie Jin
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-14 (2022)
Abstract Benign prostatic hyperplasia (BPH) is the most common and progressive urological disease in elderly men worldwide. Epidemiological studies have suggested that the speed of disease progression varies among individuals, while the pathophysiolo
Externí odkaz:
https://doaj.org/article/0f14eab5f3884b2cacbd8880bbdc0f11
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 65-81 (2021)
Isocitrate dehydrogenase (IDH) mutations increase (R)-2-hydroxyglutarate (R-2HG) production; however, functional mechanisms of R-2HG in regulating cholangiocarcinoma (CCA) development remain to be further investigated. We first applied the CRISPR-Cas
Externí odkaz:
https://doaj.org/article/2717652290ad4410902ed39d1182e716
Autor:
Hao Tian, Fu-ju Chou, Jing Tian, Yong Zhang, Bosen You, Chi-Ping Huang, Shuyuan Yeh, Yuanjie Niu, Chawnshang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Background Early studies indicated that ASC-J9®, an androgen receptor (AR) degradation enhancer, could suppress the prostate cancer (PCa) progression. Here we found ASC-J9® could also suppress the PCa progression via an AR-independent mech
Externí odkaz:
https://doaj.org/article/10a90f593d664ad88f99c8b92059e65d
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1779-1799 (2020)
Data analysis of clinical samples suggests that higher estrogen receptor α (ERα) expression could be associated with worse overall survival in some patients with non‐small‐cell lung cancer (NSCLC). Immunofluorescence results further showed that
Externí odkaz:
https://doaj.org/article/6266f976bb8f49cd9a87312a23f20001
Autor:
Keliang Wang, Jie Luo, Shuyuan Yeh, Bosen You, Jialin Meng, Philip Chang, Yuanjie Niu, Gonghui Li, Changxue Lu, Yezi Zhu, Emmanuel S. Antonarakis, Jun Luo, Chi-Ping Huang, Wanhai Xu, Chawnshang Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Castration resistant prostate cancer patients treated with enzalutamide may develop resistance to the drug. Here, the authors report that monoamine oxidase-A expression is increased in these resistant tumors and that the antidepressants phenelzine/cl
Externí odkaz:
https://doaj.org/article/e9d6def113e84a60bc881fcbffc3cdfb
Autor:
Jie Luo, Keliang Wang, Shuyuan Yeh, Yin Sun, Liang Liang, Yao Xiao, Wanhai Xu, Yuanjie Niu, Liang Cheng, Sankar N. Maity, Runze Jiang, Chawnshang Chang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The induction of neuroendocrine differentiation occurs in enzalutamide treated castration resistant prostate cancer. Here, the authors show that lncRNA-21 mediates enzalutamide induced neuroendocrine differentiation through EZH2/STAT axis and EZH2 in
Externí odkaz:
https://doaj.org/article/ce2fec008477481fbe8be007e5be6a47
Autor:
Chi-Ping Huang, Jinbo Chen, Chi-Cheng Chen, Guodong Liu, Yong Zhang, Edward Messing, Shuyuan Yeh, Chawnshang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background The current chemotherapy regimens may extend survival for patients with metastatic bladder cancer (BCa) for a few months, but eventually most patients succumb to disease because they develop resistance to their chemotherapy. Metho
Externí odkaz:
https://doaj.org/article/af49b2367d2b42b0af0e1561863d6e41
Autor:
Fu-Ju Chou, Yuhchyau Chen, Dong Chen, Yuanjie Niu, Gonghui Li, Peter Keng, Shuyuan Yeh, Chawnshang Chang
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 504-516 (2019)
Background: While androgen deprivation therapy (ADT) and radiotherapy (RT) are currently used together to treat locally advanced prostate cancer (PCa), RT might have the adverse effect of increasing the PCa androgen receptor (AR) protein expression,
Externí odkaz:
https://doaj.org/article/c1c2d45ea15a4b80a5f75b98f8fe4115
Autor:
Wenbin Song, Dalin He, Yule Chen, Chiuan‐Ren Yeh, Iawen Hsu, Qingbo Huang, Xu Zhang, Luke Sien‐Shih Chang, Li Zuo, Jiasheng Chen, Karen M. Doersch, Chawnshang Chang, Lei Li, Shuyuan Yeh
Publikováno v:
Molecular Oncology, Vol 12, Iss 12, Pp 2055-2071 (2018)
Renal cell carcinoma (RCC) has the third highest mortality rate among urological tumors, and 20–30% of RCC patients present with metastatic RCC at the time of diagnosis. Although recent studies have indicated that estrogen receptor β (ERβ) could
Externí odkaz:
https://doaj.org/article/2c262c8baccd422fb8fc8f7c163a0122