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Akademický článek

Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine

Autor: Shuxin Guo, Yuxuan Zheng, Zhengrong Gao, Minrun Duan, Sheng Liu, Pan Du, XiaoYu Xu, Kun Xu, Xin Zhao, Yan Chai, Peiyi Wang, Qi Zhao, George F. Gao, Lianpan Dai

Publikováno v: Cell Discovery, Vol 9, Iss 1, Pp 1-13 (2023)

Abstract Vaccination with different vaccines has been implemented globally to counter the continuous COVID-19 pandemic. However, the vaccine-elicited antibodies have reduced efficiency against the highly mutated Omicron sub-variants. Previously, we d

Externí odkaz: https://doaj.org/article/4441229bd67d4a40a61ca4794d6b77f9

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Akademický článek

Vascular Normalization Was Associated with Colorectal Tumor Regression upon Anti-PD-L1 Combinational Therapy

Autor: Yan Zhang, Jiayan Gao, Yan He, Ziwei Qi, Long Qian, Wanpei Chen, Haiyan Xu, Yanhua Yue, Xunyuan Mao, Shuxin Guo, Yan Zhou, Shuru Zhou, Songbing Qin, Xueguang Zhang, Yuhui Huang

Publikováno v: Journal of Immunology Research, Vol 2023 (2023)

Anti-PD-L1 therapy exhibits durable efficacy, but only in a small fraction of cancer patients. The immunosuppressive tumor microenvironment (TME) is a crucial obstacle that impedes cancer immunotherapy. Here, we found that anti-PD-L1 therapy coupled

Externí odkaz: https://doaj.org/article/ac5d98fa4c124389a69fad2d6c6c1464

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Akademický článek

Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance

Autor: Yanhua Yue, Yang Cao, Xunyuan Mao, Fei Wang, Peng Fan, Long Qian, Shuxin Guo, Feng Li, Yanting Guo, Tongbing Chen, Yan Lin, Weimin Dong, Yue Liu, Yuhui Huang, Weiying Gu

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Multiple myeloma (MM) remains a common hematologic malignancy with a 10-year survival rate below 50%, which is largely due to disease relapse and resistance. The lack of a simple and practical approach to establish myeloma patient-derived xenograft (

Externí odkaz: https://doaj.org/article/76a9c38f58c44d7792c0b79bd02f7a9c

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Akademický článek

Residue Monitoring of Propiconazole in the Rice–Crab Co-Culture Field and its Toxicity and Bioaccumulation to Eriocheir sinensis

Autor: Lina Yu, Changsheng Li, Yuting Zhang, Xuanjun Guo, Niannian Cao, Shuxin Guo, Sijia Wu, Xuefeng Li, Sen Pang

Publikováno v: Frontiers in Environmental Science, Vol 10 (2022)

Rice–crab co-culture is a high-benefit eco-breeding pattern that has been extensively developed in many regions of China. However, little attention has been paid to the safety of pesticides used to control rice pests in the crab–rice co-culture s

Externí odkaz: https://doaj.org/article/f42a743cd2d3400e85b9d49217c5c8f3

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Akademický článek

A Hemagglutinin Stem Vaccine Designed Rationally by AlphaFold2 Confers Broad Protection against Influenza B Infection

Autor: Dian Zeng, Jiabao Xin, Kunyu Yang, Shuxin Guo, Qian Wang, Ying Gao, Huiqing Chen, Jiaqi Ge, Zhen Lu, Limin Zhang, Junyu Chen, Yixin Chen, Ningshao Xia

Publikováno v: Viruses, Vol 14, Iss 6, p 1305 (2022)

Two lineages of influenza B viruses (IBV) co-circulating in human beings have been posing a significant public health burden worldwide. A substantial number of broadly neutralizing antibodies (bnAbs) have been identified targeting conserved epitopes

Externí odkaz: https://doaj.org/article/772285aee0ce4e67a1a698d975f233a1

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Akademický článek

Integrated resources planning in microgrids considering interruptible loads and shiftable loads

Autor: Lan ZHU, Xueying ZHOU, Xiao-Ping ZHANG, Zheng YAN, Shuxin GUO, Longjun TANG

Publikováno v: Journal of Modern Power Systems and Clean Energy, Vol 6, Iss 4, Pp 802-815 (2018)

Abstract Demand response has the potential to bring significant benefits to the optimal sizing of distributed generation (DG) resources for microgrids planning. This paper presents an integrated resources planning model considering the impact of inte

Externí odkaz: https://doaj.org/article/0b5db24356da414c8dbf5f23be634010

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