Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shutish Patel"'
Publikováno v:
Journal of Neurochemistry. 70:2459-2467
We have demonstrated previously that D1 dopamine receptors are coupled to both Gs alpha and Go alpha. We examine here the coupling between human D5 dopamine receptors and G proteins in transfected rat pituitary GH4C1 cells. Similar to D1 receptors, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cb7acecdec0bbdce273f8d83a1c773
https://doi.org/10.1046/j.1471-4159.1998.70062459.x
https://doi.org/10.1046/j.1471-4159.1998.70062459.x
Autor:
Jane M. Glick, Jerome F. Strauss, Shutish Patel, Hidemichi Watari, Peter G. Pentchev, E. Joan Blanchette-Mackie, Edward B. Neufeld, Gwo-Shing Sun, Nancy K. Dwyer
Publikováno v:
Experimental Cell Research. 255:56-66
Steroidogenic cells represent unique systems for the exploration of intracellular cholesterol trafficking. We employed cytochemical and biochemical methods to explore the expression, regulation, and function of the Niemann-Pick C1 protein (NPC1) in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b9ec9776809c138c373cf920ac1846
https://doi.org/10.1006/excr.1999.4774
https://doi.org/10.1006/excr.1999.4774
Publikováno v:
Neuroscience Research. 29:1-8
Renal DA-1 dopamine receptors in proximal tubules (PTs) of the Wistar-Kyoto (WKY) rat display pharmacological binding properties which are different from central nervous system (CNS) striatal D-1 dopamine receptors. In general, the renal DA-1 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbee590395eac81e17e62de0341509bc
https://doi.org/10.1016/s0168-0102(97)00070-9
https://doi.org/10.1016/s0168-0102(97)00070-9
Publikováno v:
Journal of Hypertension. 15:259-267
Dysfunctional dopamine neurotransmission and defective D1A receptor-G protein coupling exist in renal proximal tubules (RPT) of the spontaneously hypertensive rat (SHR).To determine whether the G proteins in SHR are abnormal, preventing formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e92d6372c225e683e483079c6612c0
https://doi.org/10.1097/00004872-199715030-00007
https://doi.org/10.1097/00004872-199715030-00007
Publikováno v:
Journal of Neurochemistry. 56:1286-1291
Striatal atrophy in Huntington's disease (HD) is characterized by selective preservation of a subclass of neurons colocalizing NADPH-diaphorase (NADPH-d), somatostatin (SS), and neuropeptide Y (NPY), which have been reported to show three- to fivefol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a51166fc7e28d6a837fd85f44d7de72
https://doi.org/10.1111/j.1471-4159.1991.tb11423.x
https://doi.org/10.1111/j.1471-4159.1991.tb11423.x
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 28(3)
Injury to the brain (e.g., stroke) results in a disruption of neuronal connectivity and loss of fundamental sensori-motor functions. The subsequent recovery of certain functions involves structural rearrangements in areas adjacent to the infarct. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4506a511e4377b393f6c6c5fda7fd59
https://pubmed.ncbi.nlm.nih.gov/17851453
https://pubmed.ncbi.nlm.nih.gov/17851453
Autor:
Nancy K. Dwyer, Edward B. Neufeld, Peter G. Pentchev, Shutish Patel, E. Joan Blanchette-Mackie, Michiko Watari, Jerome F. Strauss, Hidemichi Watari
Publikováno v:
The Journal of biological chemistry. 274(31)
Niemann-Pick type C (NPC) disease, characterized by accumulation of low density lipoprotein-derived free cholesterol in lysosomes, is caused by mutations in the NPC1 gene. We examined the ability of wild-type NPC1 and NPC1 mutants to correct the NPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715dfc8c45217fdb5f56f516448845ac
https://pubmed.ncbi.nlm.nih.gov/10419504
https://pubmed.ncbi.nlm.nih.gov/10419504
Publikováno v:
Journal of neurochemistry. 65(3)
Somatostatin (SS) and neuropeptide Y (NPY) are coproduced in a subpopulation of neurons that are selectively resistant to NMDA neurotoxicity. We have previously reported that quinolinic acid (QUIN), an NMDA receptor agonist, augments SS mRNA in cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d69d4818630f69f1920357e679d75c7
https://pubmed.ncbi.nlm.nih.gov/7643130
https://pubmed.ncbi.nlm.nih.gov/7643130
Publikováno v:
Biochemical and Biophysical Research Communications. 143:233-240
Esterification of cholesterol was investigated in primary neuroglial cultures obtained from newborn lysosomal cholesterol storage disorder (LCSD) mouse mutants. An impairment in 3H-oleic acid incorporation into cholesteryl esters was demonstrated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdffc7e39bb0f2539e0db2dd8c74427
https://doi.org/10.1016/0006-291x(87)90655-3
https://doi.org/10.1016/0006-291x(87)90655-3