Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shusuke, Yasuda"'
Autor:
Mitsuharu Masuda, Mano Horinaka, Shusuke Yasuda, Mie Morita, Emi Nishimoto, Hideki Ishikawa, Michihiro Mutoh, Toshiyuki Sakai
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 54-54 (2023)
Background: Recent advances have been achieved in the genetic diagnosis and therapies against malignancies due to a better understanding of the molecular mechanisms underlying carcinogenesis. Since active preventive methods are currently insufficient
Externí odkaz:
https://doaj.org/article/f09de25560064ee2a48c332a10f50aec
Autor:
Ayaka Imai, Mano Horinaka, Yuichi Aono, Yosuke Iizumi, Hideki Takakura, Hisako Ono, Shusuke Yasuda, Keiko Taniguchi, Emi Nishimoto, Hideki Ishikawa, Michihiro Mutoh, Toshiyuki Sakai
Publikováno v:
Biochemical and Biophysical Research Communications. 628:110-115
Colorectal cancer is a significant cause of morbidity and represents a serious public health issue in many countries. The development of a breakthrough preventive method for colorectal cancer is urgently needed. Aspirin has recently been attracting a
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
PDF file, 77K, ROS is not involved in the apoptosis induced by methylglyoxal with TRAIL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351eb56df5c1453e8dd5298308967399
https://doi.org/10.1158/1535-7163.22498057.v1
https://doi.org/10.1158/1535-7163.22498057.v1
Autor:
Toshiyuki Sakai, Osamu Ukimura, Tsuneharu Miki, Yukako Morioka, Toshiya Takamura, Yuichi Aono, Tomoyuki Taniguchi, Shusuke Yasuda, Mano Horinaka, Seijiro Toriyama
T24 or UM-UC-11 cells were treated with the indicated concentrations of OBP-801 and/or celecoxib for 48 h in T24 cells or 72 h in UM-UC-11 cells. A. Quantitative real-time RT-PCR of DR5 mRNA. The internal control was β2MG. Values show fold change in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c51d693740aed67b2197e0754ec99f2
https://doi.org/10.1158/1535-7163.22504234
https://doi.org/10.1158/1535-7163.22504234
Autor:
Toshiyuki Sakai, Osamu Ukimura, Tsuneharu Miki, Yukako Morioka, Toshiya Takamura, Yuichi Aono, Tomoyuki Taniguchi, Shusuke Yasuda, Mano Horinaka, Seijiro Toriyama
A. T24 cells were treated with the indicated concentrations of OBP-801 and/or celecoxib for 24 h. Cell lysates were subjected to immunoprecipitation with anti-DR5 antibody or an isotype control. Input cell lysates and anti-DR5 immunoprecipitates were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6c21e375ce4dc3e0fbae690d27ebff
https://doi.org/10.1158/1535-7163.22504228
https://doi.org/10.1158/1535-7163.22504228
Autor:
Toshiyuki Sakai, Osamu Ukimura, Tsuneharu Miki, Yukako Morioka, Toshiya Takamura, Yuichi Aono, Tomoyuki Taniguchi, Shusuke Yasuda, Mano Horinaka, Seijiro Toriyama
A. UM-UC-11 cells were treated with the indicated concentrations of OBP-801 and/or celecoxib for 72 h. Quantitative real-time RT-PCR of TRAIL mRNA was performed. The internal control was β2MG. Values show fold change in TRAIL mRNA expression compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c033076cddf6f19b161454aef2176a3
https://doi.org/10.1158/1535-7163.22504231
https://doi.org/10.1158/1535-7163.22504231
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
Methylglyoxal is an essential component in glycolysis and is known to be an inducer of apoptosis. Glyoxalase I (GLO1) metabolizes and inactivates methylglyoxal. GLO1 is known to be overexpressed in cancer cells and causes resistance to anticancer age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b07cabc7be41864f544c05dec1b0136
https://doi.org/10.1158/1535-7163.c.6535780.v1
https://doi.org/10.1158/1535-7163.c.6535780.v1
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
PDF file, 171K, Expression of TRAIL receptors when treated with methylglyoxal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105f39aa949f35bbbd1119ed783ec75
https://doi.org/10.1158/1535-7163.22498060
https://doi.org/10.1158/1535-7163.22498060
Autor:
Toshiyuki Sakai, Osamu Ukimura, Tsuneharu Miki, Yukako Morioka, Toshiya Takamura, Yuichi Aono, Tomoyuki Taniguchi, Shusuke Yasuda, Mano Horinaka, Seijiro Toriyama
T24 or UM-UC-11 cells were treated with the indicated concentrations of OBP-801 and/or celecoxib for 48 h in T24 cells or 72 h in UM-UC-11 cells. Quantitative real-time RT-PCR of FLIP (A) and survivin (B) mRNA were performed. The internal control was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116ddddbc9626d5616878798d353d527
https://doi.org/10.1158/1535-7163.22504237
https://doi.org/10.1158/1535-7163.22504237
Publikováno v:
Biochemical and Biophysical Research Communications. 590:55-62
Cellular senescence is a state of irreversible cell growth arrest that functions as a biological defense mechanism against severe DNA damage. Senescent cells with DNA damage produce pro-inflammatory cytokines, such as IL-6 and IL-8, and this phenomen