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Ibrutinib for patients with rituximab-refractory Waldenstrm's macro globulinaemia (iNNOVATE): an open-label substudy of an international, multicentre, phase 3 trial

Autor: Dimopoulos, MA, Trotman, J, Tedeschi, A, Matous, JRV, Macdonald, D, Tam, C, Tournilhac, O, Ma, S, Oriol, A, Heffner, LT, Shustik, C, Garcia-Sanz, R, Cornell, RF, de Larrea, CF, Castillo, JJ, Granell, M, Kyrtsonis, MC, Leblond, V, Symeonidis, A, Kastritis, E, Singh, P, Li, JL, Graef, T, Bilotti, E, Treon, S, Buske, C

Publikováno v: LANCET ONCOLOGY
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

Background In the era of widespread rituximab use for Waldenstrm's macro globulinaemia, new treatment options for patients with rituximab-refractory disease are an important clinical need. Ibrutinib has induced durable responses in previously treated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4093a88eb6ab9fae6745fd39fd30679b
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6700

Natural history of relapsed myeloma, refractory to immunomodulatory drugs and proteasome inhibitors: a multicenter IMWG study

Autor: Kumar, S.K. Dimopoulos, M.A. Kastritis, E. Terpos, E. Nahi, H. Goldschmidt, H. Hillengass, J. Leleu, X. Beksac, M. Alsina, M. Oriol, A. Cavo, M. Ocio, E.M. Mateos, M.V. O'Donnell, E.K. Vij, R. Lokhorst, H.M. Van De Donk, N.W.C.J. Min, C. Mark, T. Turesson, I. Hansson, M. Ludwig, H. Jagannath, S. Delforge, M. Kyriakou, C. Hari, P. Mellqvist, U. Usmani, S.Z. Dytfeld, D. Badros, A.Z. Moreau, P. Kim, K. Otero, P.R. Lee, J.H. Shustik, C. Waller, D. Chng, W.J. Ozaki, S. Lee, J.-J. De La Rubia, J. Eom, H.S. Rosinol, L. Lahuerta, J.J. Sureda, A. Kim, J.S. Durie, B.G.M.

Introduction of new myeloma therapies offers new options for patients refractory to immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs). In this multicenter study, patients with relapsed multiple myeloma, who have received at least three p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6e6540e641dfa980a281b8e3f282d8e6
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2954298

Updated outcomes and impact of age with lenalidomide and low-dose dexamethasone or melphalan, prednisone, and thalidomide in the randomized, phase III FIRST trial

Autor: Hulin, C. Belch, A. Shustik, C. Petrucci, M.T. Dührsen, U. Lu, J. Song, K. Rodon, P. Pégourié, B. Garderet, L. Hunter, H. Azais, I. Eek, R. Gisslinger, H. Macro, M. Dakhil, S. Goncalves, C. Leblanc, R. Romeril, K. Royer, B. Doyen, C. Leleu, X. Offner, F. Leupin, N. Houck, V. Chen, G. Ervin-Haynes, A. Dimopoulos, M.A. Facon, T.

Purpose: This analysis of the FIRST trial in patients with newly diagnosed multiple myeloma (MM) ineligible for stem-cell transplantation examined updated outcomes and impact of patient age. Patients and Methods: Patients with untreated symptomatic M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::a1c6cb853d82ab0d0612fdb331cb6894
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3085632

International myeloma working group recommendations for the diagnosis and management of myeloma-related renal impairment

Autor: Dimopoulos, M.A. Sonneveld, P. Leung, N. Merlini, G. Ludwig, H. Kastritis, E. Goldschmidt, H. Joshua, D. Orlowski, R.Z. Powles, R. Vesole, D.H. Garderet, L. Einsele, H. Palumbo, A. Cavo, M. Richardson, P.G. Moreau, P. Miguel, J.S. Vincent Rajkumar, S. Durie, B.G.M. Terpos, E. Abildgaard, N. Abonour, R. Alsina, M. Anderson, K.C. Attal, M. Avet-Loiseau, H. Badros, A. Bahlis, N.J. Barlogie, B. Bataille, R. Beksaç, M. Belch, A. Ben-Yehuda, D. Bensinger, B. Leif Bergsagel, P. Bhutani, M. Bird, J. Bladé, J. Broijl, A. Boccadoro, M. Caers, J. Chanan-Khan, A. Chari, A. Chen, W.M. Chesi, M. Anthony Child, J. Chim, C.S. Chng, W.-J. Comenzo, R. Cook, G. Crowley, J. Crusoe, E. Dalton, W. Lee Moffitt, H. Davies, F. de la Rubia, J. de Souza, C. Delforge, M. Dhodapkar, M. Dispenzieri, A. Drach, J. Drake, M. Du, J. Dytfeld, D. Facon, T. Fantl, D. Fermand, J.-P. Fernández de Larrea, C. Fonseca, R. Gahrton, G. Garćia-Sanz, R. Gasparetto, C. Gertz, M. Ghobrial, I. Gibson, J. Gimsing, P. Giralt, S. Gu, J. Hajek, R. Hardan, I. Hari, P. Hata, H. Hattori, Y. Heffner, T. Hillengass, J. Ho, J. Hoering, A. Hoffman, J.E. Hou, J. Huang, J. Hungria, V. Ida, S. Jagannath, S. Jakubowiak, A.J. Johnsen, H.E. Jurczyszyn, A. Kaiser, M. Kaufman, J. Kawano, M. Korde, N. Kovacs, E. Krishnan, A. Kristinsson, S. Kröger, N. Kumar, S. Kyle, R.A. Kyriacou, C. Lacy, M. Lahuerta, J.J. Landgren, O. Larocca, A. Laubach, J. da Costa, F.L. Lee, J.-H. Leiba, M. Leleu, X. Lentzsch, S. Lokhorst, H. Lonial, S. Lu, J. Mahindra, A. Maiolino, A. Manasanch, E.E. Mark, T. Mateos, M.-V. Mazumder, A. McCarthy, P. Mehta, J. Mellqvist, U.-H. Mikhael, J. Morgan, G. Munshi, N. Nahi, H. Nawarawong, W. Niesvizky, R. Nouel, A. Novis, Y. Ocio, E. O'Dwyer, M. O'Gorman, P. Orfao, A. Otero, P.R. Paiva, B. Pavlovsky, S. Pilarski, L. Pratt, G. Qui, L. Raje, N. Reece, D. Reiman, A. Remaggi, G. Richter, J. Serra, E.R. Morales, A.R. Romeril, K.R. Roodman, D. Rosiñol, L. Rossi, A. Roussel, M. Russell, S. Schjesvold, F. Schots, R. Sevcikova, S. Sezer, O. Shah, J.J. Shimizu, K. Shustik, C. Siegel, D. Singhal, S. Spencer, A. Stadtmauer, E. Stewart, K. Tan, D. Terragna, C. Tosi, P. Tricot, G. Turesson, I. Usmani, S. Van Camp, B. Van de Donk, N. Van Ness, B. Van Riet, I. Broek, I.V. Vanderkerken, K. Vescio, R. Vij, R. Voorhees, P. Waage, A. Wang, M. Weber, D. Weiss, B.M. Westin, J. Wheatley, K. Zamagni, E. Zonder, J. Zweegman, S.

Purpose: The aim of the International Myeloma Working Group was to develop practical recommendations for the diagnosis and management of multiple myeloma–related renal impairment (RI). Methods: Recommendations were based on published data through D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::48c145964f6a240a1f15959427f45cd0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3085510