Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shushan Yan"'
Autor:
Shushan Yan, Tie Liu, Haobin Zhao, Chunbo Zhao, Yuxin Zhu, Wenqing Dai, Wenchang Sun, Honggang Wang, Junxi Sun, Lu Zhao, Donghua Xu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionAccumulating evidence has supported that gut microbiota and metabolite profiles play indispensable roles in the pathogenesis of colorectal cancer (CRC), which ranks as the third most common cancer and the second leading cause of cancer-re
Externí odkaz:
https://doaj.org/article/8bf3c5fbc18b48cf960f627e9c7c9909
circRNA_17725 Promotes Macrophage Polarization towards M2 by Targeting FAM46C to Alleviate Arthritis
Autor:
Chunjuan Yang, Biao Ni, Chaoran Li, Wenchang Sun, Zhangxue Wang, Hui Wang, Xinyue Hou, Shushan Yan, Xiaodong Wang, Donghua Xu
Publikováno v:
Mediators of Inflammation, Vol 2023 (2023)
Accumulating studies have implicated that circular RNAs (circRNAs) play vital roles in the pathogenesis of rheumatoid arthritis (RA). Dysregulation of macrophage polarization leads to immune homeostatic imbalance in RA. However, the altering effects
Externí odkaz:
https://doaj.org/article/6e22c9bfa7a44fb3961c328f6f835a17
Autor:
Shushan Yan, Shufeng Wang, Xinyi Wang, Wenqing Dai, Jinjin Chu, Min Cheng, Zhiliang Guo, Donghua Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metabolic reprogramming plays a critical role in colorectal cancer (CRC). It contributes to CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells. Glucose metabolic reprogramming is common in carcinogenesis and cance
Externí odkaz:
https://doaj.org/article/b2c3264ebabc4d0ca6b3740a45d9104c
Autor:
Lili Zhang, Zhisheng Wang, Xiaona Zhang, Lu Zhao, Jinjin Chu, Haibo Li, Wenchang Sun, Chunjuan Yang, Hui Wang, Wenqing Dai, Shushan Yan, Xiaohua Chen, Donghua Xu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Diabetic nephropathy (DN) is the primary cause of end-stage renal disease. Accumulating studies have implied a critical role for the gut microbiota in diabetes mellitus (DM) and DN. However, the precise roles and regulatory mechanisms of the
Externí odkaz:
https://doaj.org/article/e546e0d770b4471a986d32fc588e96c4
Autor:
Jinjin Chu, Xianzhu Fang, Zhonghou Sun, Linlin Gai, Wenqing Dai, Haibo Li, Xinyi Yan, Jinke Du, Lili Zhang, Lu Zhao, Donghua Xu, Shushan Yan
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Colorectal cancer (CRC) is the third prevalent cancer worldwide, the morbidity and mortality of which have been increasing in recent years. As molecular targeting agents, anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (McAbs) have
Externí odkaz:
https://doaj.org/article/70242fdd2e5b4c33b75f011c53f439b7
Autor:
Chunjuan Yang, Jianmei Sun, Yipeng Tian, Haibo Li, Lili Zhang, Jinghan Yang, Jinghua Wang, Jiaojiao Zhang, Shushan Yan, Donghua Xu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is a common autoimmune connective tissue disease with unclear etiology and pathogenesis. Mesenchymal stem cell (MSC) and MSC derived extracellular vesicles (EVs) play important roles in regulating innate and adaptiv
Externí odkaz:
https://doaj.org/article/370f6f8ac8af41a38e9eebb34637c9de
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by symmetrical and inflammatory destruction of distal joints. Its primary pathological characters are synovitis and vasculitis. Accumulating studies have implicated the cr
Externí odkaz:
https://doaj.org/article/29d4f0ad0f2c4d659ca87b2b8d56e463
Autor:
Shushan Yan, Pingping Wang, Jinghua Wang, Jinghan Yang, Hongying Lu, Chengwen Jin, Min Cheng, Donghua Xu
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Accumulating studies have suggested that long non-coding RNAs (lncRNAs) have drawn more and more attention in rheumatoid arthritis (RA), which can function as competitive endogenous RNAs (ceRNAs) in inflammation and immune disorders. Previously, we h
Externí odkaz:
https://doaj.org/article/b462204da65d4216b3cd2202181ec6ae
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Accumulated studies have implicated microRNAs (miRNAs) exert modifying effects on colorectal cancer (CRC). Protein tyrosine phosphatase, receptor type O (PTPRO) has been identified as a tumor suppressor in several kinds of cancer, including CRC. Prev
Externí odkaz:
https://doaj.org/article/103cfa40678f4dc48d598c3e2047b1c3
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Methyltransferase-like 3 (METTL3), an RNA N6-methyladenosine (m6A) methyltransferase, is essential for the m6A mRNA modification. As a key enzyme of m6A methylation modification, METTL3 has been implicated in immune and inflammation regulation. Howev
Externí odkaz:
https://doaj.org/article/923a69eb6dc84acdb4c3e4360a4d9c52