Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shushan Gao"'
Publikováno v:
Molecules, Vol 29, Iss 6, p 1328 (2024)
(R)-Homobenzylic amines are key structural motifs present in (R)-selegiline, a drug indicated for the treatment of early-stage Parkinson’s disease. Herein, we report a new short chemoenzymatic approach (in 2 steps) towards the synthesis of (R)-sele
Externí odkaz:
https://doaj.org/article/4d4daa009f4049818d6840a63f6b4636
Publikováno v:
Foods, Vol 12, Iss 14, p 2794 (2023)
To reduce the usage of petroleum-based plastic products, a lignin-based film material named aminated lignin/Fe(III)/PVA was developed. The mixture of 8 g lignin, 12 mL diethylenetriamine, 200 mL NaOH solution (0.4 mol·L−1), and 8 mL formaldehyde w
Externí odkaz:
https://doaj.org/article/63f6ba6f4d004c5c9842b3868e3994c4
Autor:
Tingting Hao, Zhoujie Xie, Min Wang, Liwei Liu, Yuwei Zhang, Weicang Wang, Zhao Zhang, Xuejin Zhao, Pengwei Li, Zhengyan Guo, Shushan Gao, Chunbo Lou, Guodong Zhang, Justin Merritt, Geoff P. Horsman, Yihua Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Anaerobic bacteria represent a rich source of biological and chemical diversity but are difficult to cultivate and there is a lack of heterologous expression systems. Here the authors develop an expression system based on S. mutans UA159 for biosynth
Externí odkaz:
https://doaj.org/article/e7f2bd25d9b24d798c21096cacfced89
Autor:
Shengming Zhang, Tiehan Mei, Chonghao Zhu, Huimin Shang, Shushan Gao, Liyuan Qin, Haitao Chen
Publikováno v:
Energies, Vol 15, Iss 10, p 3636 (2022)
Chemical pretreatment can significantly improve the enzymatic hydrolysis efficiency of lignocellulosic biomass, thereby improving the yield of sugar materials for the production of cellulosic ethanol, but commonly used acid–base catalysts are diffi
Externí odkaz:
https://doaj.org/article/914e11bc8c804eb2977a736c676ce60e
Publikováno v:
Organic & Biomolecular Chemistry. 21:4181-4184
An engineered imine reductase was used to catalyze the reductive amination of N-Boc-4-oxo-azepane and diverse amines to synthesize S-azepane-4-amines.
Publikováno v:
Metabolic Engineering. 72:56-65
We have engineered brewer's yeast as a general platform for de novo synthesis of diverse β-lactam nuclei starting from simple sugars, thereby enabling ready access to a number of structurally different antibiotics of significant pharmaceutical impor
Autor:
Shengming Zhang, Liangfei Ma, Shushan Gao, Chonghao Zhu, Yehong Yan, Xiaohan Liu, Longhai Li, Haitao Chen
Publikováno v:
Processes; Volume 10; Issue 6; Pages: 1210
To value-added utilization of the rice straw, two types of lignin were extracted from the by-products of sugar production. The ether-extracted lignin with a purity of 98.7% was extracted from the pretreatment filtrate with two times the concentrated
Autor:
Shiyi Song, Yingying Jiang, Ruidong Chen, Wencheng Su, Weinan Liang, Dameng Yang, Jincheng Li, Wuyuan Zhang, Shushan Gao, Bo Yuan, Ge Qu, Zhoutong Sun
Publikováno v:
ChemBioChem. 23
Deacetoxycephalosporin C synthase (DAOCS) catalyzes the transformation of penicillin G to phenylacetyl-7-aminodeacetoxycephalosporanic acid (G-7-ADCA) for which it depends on 2-oxoglutarate (2OG) as co-substrate. However, the low activity of DAOCS an
Autor:
Lan, Jiang, Guoliang, Zhu, Jianying, Han, Chengjian, Hou, Xue, Zhang, Zhixin, Wang, Weize, Yuan, Kangjie, Lv, Zhanren, Cong, Xinye, Wang, Xiangyin, Chen, Loganathan, Karthik, Huanting, Yang, Xuyuan, Wang, Gaoyi, Tan, Guang, Liu, Liya, Zhao, Xuekui, Xia, Xiangyang, Liu, Shushan, Gao, Lei, Ma, Mei, Liu, Biao, Ren, Huanqin, Dai, Ronald J, Quinn, Tom, Hsiang, Jingyu, Zhang, Lixin, Zhang, Xueting, Liu
Publikováno v:
Applied microbiology and biotechnology. 105(13)
Fungal terpenoids catalyzed by bifunctional terpene synthases (BFTSs) possess interesting bioactive and chemical properties. In this study, an integrated approach of genome mining, heterologous expression, and in vitro enzymatic activity assay was us
Autor:
Liwei Liu, Justin Merritt, Shushan Gao, Weicang Wang, Zhengyan Guo, Geoff P. Horsman, Tingting Hao, Yuwei Zhang, Zhao Zhang, Yihua Chen, Pengwei Li, Chunbo Lou, Guodong Zhang, Min Wang, Zhoujie Xie, Xuejin Zhao
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Anaerobic bacteria represent an overlooked rich source of biological and chemical diversity. Due to the challenge of cultivation and genetic intractability, assessing the capability of their biosynthetic gene clusters (BGCs) for secondary metabolite