Výsledky vyhledávání - "Shusei Yamamoto"

Akademický článek

Potential of a Novel Chemical Compound Targeting Matrix Metalloprotease-13 for Early Osteoarthritis: An In Vitro Study

Autor: Junko Inagaki, Airi Nakano, Omer Faruk Hatipoglu, Yuka Ooka, Yurina Tani, Akane Miki, Kentaro Ikemura, Gabriel Opoku, Ryosuke Ando, Shintaro Kodama, Takashi Ohtsuki, Hirosuke Yamaji, Shusei Yamamoto, Eri Katsuyama, Shogo Watanabe, Satoshi Hirohata

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 5, p 2681 (2022)

Osteoarthritis is a progressive disease characterized by cartilage destruction in the joints. Matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) play key roles in osteoarthritis progression.

Externí odkaz: https://doaj.org/article/693b597041ca445e8eed6f894584b5b1

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Therapeutic effect of ouabagenin, a novel liver X receptor agonist, on atherosclerosis in nonalcoholic steatohepatitis in SHRSP5/Dmcr rat model

Autor: Shusei Yamamoto, Ikumi Sato, Moe Fujii, Mai Kakimoto, Koki Honma, Sora Kirihara, Hinako Nakayama, Taketo Fukuoka, Satoru Tamura, Minoru Ueda, Satoshi Hirohata, Shogo Watanabe

Publikováno v: Canadian Journal of Physiology and Pharmacology.

The liver X receptor (LXR) can enhance cholesterol transporters, which could remove excess cholesterol from foam cells in atheromas. LXR has two subtypes: LXRα, which aggravates hepatic lipid accumulation, and LXRβ, which does not. In 2018, ouabage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4967c096cf220884d52d508d4cd980bc
https://doi.org/10.1139/cjpp-2022-0532

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Uric acid elevation by fructose overload exacerbates NASH and atherosclerosis via oxidative stress

Autor: Shogo Watanabe, Moe Fujii, Mai Kakimoto, Ikumi Sato, Koki Honma, Sora Kirihara, Hinako Nakayama, Taketo Fukuoka, Satoshi Hirohata, Kazuya Kitamori, Shang Ran, Shusei Yamamoto

Publikováno v: Current Nutrition & Food Science. 19

Background: Nonalcoholic steatohepatitis (NASH) is well associated with an increased risk of cardiovascular disease (CVD), regardless of risk factors for metabolic syndrome. However, intermediary factors between NASH and CVD remain unknown. In recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dae8fe49ff867be3f5f499ce1b9006ca
https://doi.org/10.2174/1573401319666230508150159

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Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism

Autor: Ikumi Sato, Shusei Yamamoto, Mai Kakimoto, Moe Fujii, Koki Honma, Shota Kumazaki, Mami Matsui, Hinako Nakayama, Sora Kirihara, Shang Ran, Shinichi Usui, Ryoko Shinohata, Kazuya Kitamori, Satoshi Hirohata, Shogo Watanabe

Publikováno v: Pharmacological reports : PR. 74(4)

Non-alcoholic steatohepatitis (NASH) is a progressive subtype of non-alcoholic fatty liver disease (NAFLD) that is closely related to cardiovascular disease (CVD). Nitric oxide (NO) plays a critical role in the control of various biological processes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edc442ef2356deac661267dc3224952
https://pubmed.ncbi.nlm.nih.gov/35819592

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Spontaneous Vesicle Formation of Monododecenyl Phosphonic Acid in Water

Autor: Tomohiro Imura, Hideki Sakai, Toshiaki Taira, Yuki Ishizaki, Kenichi Sakai, Shusei Yamamoto

Publikováno v: Journal of Oleo Science. 68:1223-1230

We report the synthesis of amphiphilic dodecenyl phosphonic acid PC12 from vinylphosphonic acid, a reactive phosphonic acid intermediate. The trans-P-C=C moiety enabled PC12 to disperse well in water. Surface tension and dynamic light scattering meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5943b0398dce2f2ceac9900b230190f
https://doi.org/10.5650/jos.ess19164

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Bile acids aggravate nonalcoholic steatohepatitis and cardiovascular disease in SHRSP5/Dmcr rat model

Autor: Yukio Yamori, Shusei Yamamoto, Shota Kumazaki, Satoshi Hirohata, Shang Ran, Shogo Watanabe, Kazuya Kitamori, Natsumi Akiyama, Natsuki Fukuhama, Miku Sakai, Ikumi Sato

Publikováno v: Experimental and molecular pathology. 114

Background and aims Nonalcoholic steatohepatitis (NASH) is linked to an increased risk of cardiovascular disease, regardless of the risk factors in metabolic syndrome. However, the intermediary factors between NASH and cardiovascular disease are stil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9598564671462db4ee514383fb85f9d4
https://pubmed.ncbi.nlm.nih.gov/32246926

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Basic characteristics between mechanomyogram and muscle force during twitch and tetanic contractions in rat skeletal muscles

Autor: Ikumi, Sato, Shusei, Yamamoto, Mai, Kakimoto, Moe, Fujii, Koki, Honma, Shota, Kumazaki, Mami, Matsui, Hinako, Nakayama, Sora, Kirihara, Shang, Ran, Satoshi, Hirohata, Shogo, Watanabe

Publikováno v: Journal of Electromyography and Kinesiology. 62:102627

The mechanomyogram (MMG) is a signal measured by various vibration sensors for slight vibrations induced by muscle contraction, and it reflects the muscle force during electrically induced-contraction or until 60%-70% maximum voluntary contraction, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686d8aed83be13c2e296dc02884992e0
https://doi.org/10.1016/j.jelekin.2021.102627

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Bile Acid Metabolism is an Intermediary Factor between Non-Alcoholic Steatohepatitis and Ischemic Heart Disease in SHRSP5/Dmcr Rats

Autor: Ikumi Sato, Shusei Yamamoto, Shogo Watanabe, Mari Mori, Shang Ran, Takashi Ohtsuki, Shun Sasaki, Kazuya Kitamori, Shota Kumazaki, Satoshi Hirohata, Shinichi Usui, Nozomi Maruyama, Ryoko Shinohata, Mayu Nakamura, Rina Tagashira, Yukio Yamori

Publikováno v: Journal of Nutrition & Food Sciences.

The non-alcoholic steatohepatitis (NASH) increases the cardiovascular risk regardless of risk factors in metabolic syndrome. The stroke-prone (SP) spontaneously hypertensive rats (SHRSP5/Dmcr), fed a high-fat and -cholesterol (HFC) diet and administe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e65c52c60f748c7a81c1a5a1e728099
https://doi.org/10.35248/2155-9600.19.9.763

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