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MicroRNA expression profiling of peripheral blood mononuclear cells associated with syphilis

Autor: Tao Huang, Jun Zhang, Wujian Ke, Xiaohui Zhang, Wentao Chen, Jieyi Yang, Yiwen Liao, Fangwen Liang, Shuqing Mei, Mingjiu Li, Zhenzhou Luo, Qiwei Zhang, Bin Yang, Heping Zheng

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)

Abstract Background Treponema pallidum (T. pallidum) infection evokes significant immune responses, resulting in tissue damage. The immune mechanism underlying T. pallidum infection is still unclear, although microRNAs (miRNAs) have been shown to inf

Externí odkaz: https://doaj.org/article/514f3ee70d464f3fa2ec2e3b457306f7

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MicroRNA expression profiling of peripheral blood mononuclear cells associated with syphilis

Autor: Wujian Ke, Fangwen Liang, Xiaohui Zhang, Jun Zhang, Heping Zheng, Jieyi Yang, Mingjiu Li, Yiwen Liao, Qiwei Zhang, Bin Yang, Wentao Chen, Shuqing Mei, Zhenzhou Luo, Tao Huang

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Infectious Diseases

BackgroundTreponema pallidum(T. pallidum) infection evokes significant immune responses, resulting in tissue damage. The immune mechanism underlyingT. palliduminfection is still unclear, although microRNAs (miRNAs) have been shown to influence immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cb31c1541986effdb4a6ea6778edd6
https://doi.org/10.21203/rs.2.9964/v6

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MicroRNA-101-3p Downregulates TLR2 Expression, Leading to Reduction in Cytokine Production by Treponema pallidum-Stimulated Macrophages

Autor: Jieyi Yang, Heping Zheng, Fangwen Liang, Chengsong Wan, Fei Zou, Bin Yang, Liuyuan Wang, Jun Zhang, Xiaohui Zhang, Qiwei Zhang, Shuqing Mei, Zhili Rong, Wujian Ke, Tao Huang

Publikováno v: The Journal of investigative dermatology. 140(8)

Treponema pallidum (Tp) infection–induced immune responses can cause tissue damage. However, the underlying mechanism by which Tp infection induces immune response is unclear. Recent studies suggest a regulatory role of microRNAs in host immunity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db924de88674264498f87180f8e5d6be
https://pubmed.ncbi.nlm.nih.gov/31930972

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