Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Shuqin Han"'
Autor:
Shaobo Ou-yang, Shuqin Han, Dan Sun, Hongping Wu, Jianping Chen, Ying Cai, Dongmei Yin, Huidan Ou-yang, Lan Liao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To properly repair and maintain implants, which are bone tissue implants that replace natural tooth roots, it is crucial to accurately identify their brand and specification. Deep learning has demonstrated outstanding capabilities in analysi
Externí odkaz:
https://doaj.org/article/57cf84ebd9a44a12aeea300674a0499c
Autor:
Tsogzolmaa Ganbold, Qingming Bao, Hai Xiao, Dolgorsuren Zurgaanjin, Caifeng Liu, Shuqin Han, Agula Hasi, Huricha Baigude
Publikováno v:
Nanomaterials, Vol 12, Iss 12, p 2072 (2022)
Ischemic stroke activates toll-like receptor 4 (TLR4) signaling, resulting in proinflammatory polarization of microglia and secondary neuronal damage. Herein, we report a novel lipid-nanoparticle (LNP)-mediated knockdown of TLR4 in microglia and amel
Externí odkaz:
https://doaj.org/article/4bf9362dbf394d55b9003120f4d4da9d
Autor:
Ehexige Ehexige, Mingming Bao, Purevbat Bazarjav, Xiang Yu, Hai Xiao, Shuqin Han, Huricha Baigude
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 285 (2020)
Cutaneous melanoma is the most aggressive skin cancer with notorious drug resistance. Inhibition of immune checkpoint molecules is one of the most promising approaches for cancer therapy. Herein, we show that RNAi mediated silencing of STAT3 expressi
Externí odkaz:
https://doaj.org/article/76f52d69c88c4639b16892968426069e
Publikováno v:
Molecules, Vol 24, Iss 18, p 3413 (2019)
Lipid nanoparticles (LNP) are the most potent carriers for the delivery of nucleic acid-based therapeutics. The first FDA approved a short interfering RNA (siRNA) drug that uses a cationic LNP system for the delivery of siRNA against human transthyre
Externí odkaz:
https://doaj.org/article/4bdf5251f6b049429eaf9465406f3e05
Autor:
Shiming Bai, Davaanyam Budragchaa, Shuqin Han, Taisei Kanamoto, Hideki Nakashima, Takashi Yoshida
Publikováno v:
International Journal of Polymer Science, Vol 2015 (2015)
Sulfated glucopyranans having long alkyl groups were prepared by the ring-opening copolymerization of benzylated 1,6-anhydroglucopyranose with 3-O-octadecyl 1,6-anhydro-β-d-glucopyranose monomers, and subsequent deprotection and sulfation. Water-sol
Externí odkaz:
https://doaj.org/article/9e21556cce044db691414e59cb657801
Publikováno v:
RSC Advances. 12:21567-21573
The amino groups in the head group of a cationic lipid play a determinative role regarding the nucleic acid delivery efficiency of the LNP formulated from lipids. Herein, we designed four types of lipid bearing different amine-containing branched hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cc71d294f944dc2c6330189cb9ba98
https://doi.org/10.1039/d2ra03347j
https://doi.org/10.1039/d2ra03347j
Publikováno v:
International Journal of Biological Macromolecules. 193:866-873
Receptor-mediated endocytosis has been used for tissue targeted delivery of short interfering RNA (siRNA) drugs. Herein, we investigated adenosine receptor (AR) as a candidate for receptor-mediated siRNA internalization. We synthesized adenosine func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c496f6bbb02a685ec7c09747f8cbb98f
https://doi.org/10.1016/j.ijbiomac.2021.10.138
https://doi.org/10.1016/j.ijbiomac.2021.10.138
Autor:
Xiang Yu, Mingming Bao, Hai Xiao, Muqier Muqier, Qingming Bao, Yifeng Li, Huricha Baigude, Shuqin Han
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 33:465-480
Cationic polysaccharides have shown excellent ability of nucleic acids delivery. However, cationic curdlan derivatives with high degree of amination cause damage to the cell membrane and induce considerable cytotoxicity, limiting their in vivo applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0157e828a4d7eb8f7a54d36faa66f42
https://doi.org/10.1080/09205063.2021.1992589
https://doi.org/10.1080/09205063.2021.1992589
Publikováno v:
Coatings; Volume 12; Issue 10; Pages: 1557
The shuttle effect and slow REDOX kinetics of lithium polysulfides (LiPSs) lead to low sulfur utilization rate, short cycle life, poor rate performance, which hinder the application of Li–S batteries. Herein, the Ni-NiS/NCF heterojunction composite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75aa1f8860fbc7bf054eb0995e960203
Publikováno v:
RSC Advances. 11:32549-32558
The pro-inflammatory polarization of microglia after stroke is one of the major causes of secondary brain injury. Downregulation of the gene involved in canonical inflammatory pathways in glial cells can exert neuroprotective effects via inhibiting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f847da1106ad05d14d81cc990bf743
https://doi.org/10.1039/d1ra04293a
https://doi.org/10.1039/d1ra04293a