Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shuqian Jing"'
Autor:
Jenny Hu, Yanbin Yu, Hong Han, Francesca Civoli, Yao Zhuang, John Thomas, Steve Swanson, Shuqian Jing, Shalini Gupta
Publikováno v:
Cells, Vol 3, Iss 1, Pp 79-91 (2014)
BAFF has a critical role in B-cell survival, maturation and function, which makes its pathway a prime therapeutic target for various autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis and Sjögren’s syndrome. A ce
Externí odkaz:
https://doaj.org/article/dc5e74bbeb364f6dbd8629aadc73adbc
Publikováno v:
Applied Microbiology and Biotechnology
G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, are among the most important targets against which many small molecule drugs have been developed. However, only two antibody drugs targeting GPCRs have been appr
Publikováno v:
Journal of Cellular Physiology. 231:172-180
SHC3 is exclusively expressed in postmitotic neurons, while SHC1 is found in neural stem cells and neural precursor cells but absent in mature neurons. In this study, we discovered that suppression of p52SHC1 expression by RNA interference resulted i
Autor:
Dacheng He, Haiping Que, Qinxue Ding, Yaojun Guo, Shuguang Yang, Shuqian Jing, Shaojun Liu, Congjian Zhao, Hongxia Wang, Kaihua Wei, Yufeng Jia
Publikováno v:
Journal of Proteomics & Bioinformatics. :074-081
Fractionation efficiency and protein characterization of neural soluble and insoluble proteins by sequential extraction was scrutinized by gel-based proteomic analysis. Spinal cord proteins of adult rats were first extracted with aqueous buffer (frac
A non-radioactive method for detecting neutralizing antibodies against therapeutic proteins in serum
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 45:583-589
The presence of neutralizing antibodies against protein therapeutics continues to cause concern in the biomedical field. These antibodies not only reduce the efficacy of the protein therapeutics, but may also block the normal function of their endoge
Autor:
Bingyao Chen, Shaoxiang Xiong, Congjian Zhao, Zhe Wu, Hongxia Wang, Fanwen Kong, Yaojun Guo, Shaojun Liu, Yufeng Jia, Shuqian Jing, Haiping Que, Qinxue Ding
Publikováno v:
PROTEOMICS. 6:505-518
The inability of the CNS to regenerate in adult mammals propels us to reveal associated proteins involved in the injured CNS. In this paper, either thoracic laminectomy (as sham control) or thoracic spinal cord transection was performed on male adult
Publikováno v:
Journal of cellular physiology. 231(1)
SHC3 is exclusively expressed in postmitotic neurons, while SHC1 is found in neural stem cells and neural precursor cells but absent in mature neurons. In this study, we discovered that suppression of p52SHC1 expression by RNA interference resulted i
Autor:
Zheng Hu, Yan Bin Yu, Dave Hill, Josette Carnahan, Diane Duryea, Marlese Pisegna, Frank Asuncion, Gwyneth Van, Kathy Christensen, Brad Bolon, Shuqian Jing, Xiao-Qiang Yan, John E. Tarpley, Todd Juan, Robert Rosenfeld, Hosung Min, Sheila Scully, Ken Wild, Steve Kaufman, James McCabe, W. Scott Simonet
Publikováno v:
Toxicologic Pathology. 32:275-294
Artemin (ART) signals through the GFR α—3/RET receptor complex to support sympathetic neuron development. Here we show that ART also influences autonomic elements in adrenal medulla and enteric and pelvic ganglia. Transgenic mice over-expressing A
Autor:
David Chang, Jilin Sun, Marina Stolina, Shuqian Jing, Raffi Manoukian, Sheila Scully, Richard Yeh, Hung Q. Nguyen, Margaret L. DeRose, Gwyneth Van, Kristie Clarkin, Giorgio Senaldi, Dimitry M. Danilenko, Mee Rhan Kim, Eugene Medlock, Scott M. Silbiger, Yan Bin Yu, Gary Elliott
Publikováno v:
Blood. 100:2330-2340
We have identified and cloned a novel human cytokine with homology to cytokines of the interleukin-17 (IL-17) family, which we have termed human IL-17E (hIL-17E). With the identification of several IL-17 family members, it is critical to understand t