Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shuobo Boboila"'
Autor:
Shuobo Boboila, Shunpei Okochi, Debarshi Banerjee, Sunjay Barton, Cherease Street, Ariela L. Zenilman, Qi Wang, Robyn D. Gartrell, Yvonne M. Saenger, David Welch, Cheng-Chia Wu, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17399- (2023)
Purpose: The mortality in patients with MYCN-amplified high-risk neuroblastoma remains greater than 50% despite advances in multimodal therapy. Novel therapies are urgently needed that requires preclinical evaluation in appropriate mice models. Combi
Externí odkaz:
https://doaj.org/article/fa27762c9bb44152888c6166e7048148
Autor:
Douglas K. Marks, Robyn D. Gartrell, Margueritta El Asmar, Shuobo Boboila, Thomas Hart, Yan Lu, Qingfei Pan, Jiyang Yu, Hanina Hibshoosh, Hua Guo, Eleni Andreopoulou, Lisa Wiechmann, Katherine Crew, Joseph Sparano, Dawn Hershman, Eileen Connolly, Yvonne Saenger, Kevin Kalinsky
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: The PI3K/Akt/mTOR pathway in part impacts tumorigenesis through modulation of host immune activity. To assess the effects of Akt inhibition on the tumor micro-environment (TME), we analyzed tumor tissue from patients with operable hormone
Externí odkaz:
https://doaj.org/article/161752bec1d44d66a615bab9381ecca5
Autor:
Shuobo Boboila, Shunpei Okochi, debarshi banerjee, Sunjay Barton, Cherease Street, Ariela L. Zenilman, Robyn D. Gartrell, Yvonne Saenger, David Welch, Cheng-Chia Wu, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly
Publikováno v:
SSRN Electronic Journal.
Autor:
Ariela L. Rumeld, Darrell J. Yamashiro, Cherease Street, Sunjay M. Barton, Debarshi Banerjee, Angela Kadenhe-Chiweshe, Shunpei Okochi, Shuobo Boboila, Peter Grabham, Eileen P. Connolly
Publikováno v:
International journal of radiation oncology, biology, physics
Purpose: The aim of this study is to characterize the effects of high-dose radiation therapy (HDRT) on Notch signaling components of the tumor vasculature. Methods and Materials: Human umbilical vein endothelial cells monolayers were exposed to diffe
Autor:
Rami Vanguri, Tahsin Kurc, Joel H. Saltz, Rajarsi Gupta, Dimitris Samaras, Shahira Abousamra, Kevin Gardner, Han Le, Hua Guo, Kevin Kalinsky, Shuobo Boboila, Le Hou, Hanina Hibshoosh, Eileen P. Connolly
Publikováno v:
Cancer Research. 80:P3-09
Background: High levels of stromal tumor-infiltrating lymphocytes (sTILs) are significantly associated with chemosensitivity and improved overall survival for patients with triple negative breast cancer (TNBC). Our aim is to determine if we can signi
Autor:
Douglas K. Marks, Hanina Hibshoosh, Hua Guo, Kathleen Fenn, Eileen P. Connolly, Kevin Kalinsky, Shuobo Boboila, Rami Vanguri
Publikováno v:
Cancer Research. 80:P6-10
Background: In patients (pts) with early stage HER2-positive breast cancer (BC) who are treated with combination neoadjuvant chemotherapy (NAC) and HER2-targeted therapy, recent studies report that increased tumor infiltrating lymphocyte (TIL) densit
Autor:
Andrea Califano, Jose M. Silva, Darrell J. Yamashiro, Eileen P. Connolly, Jiyang Yu, Presha Rajbhandari, Debarshi Banerjee, Shuobo Boboila, Angela Kadenhe-Chiweshe, Jessica J. Kandel, Gonzalo Lopez
Publikováno v:
Oncogene
Despite the identification of MYCN amplification as an adverse prognostic marker in neuroblastoma, MYCN inhibitors have yet to be developed. Here, by integrating evidence from a whole-genome shRNA library screen and the computational inference of mas
Autor:
Joel H. Saltz, H. Guo, H. Le, Qi Wang, Rajarsi P. Gupta, Le Hou, Tahsin Kurc, Dimitris Samaras, Eileen P. Connolly, Kevin Gardner, Rami Vanguri, Hanina Hibshoosh, Kevin Kalinsky, Shuobo Boboila, Shahira Abousamra
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 108:e48
Autor:
Darrell J. Yamashiro, Sunjay M. Barton, Shuobo Boboila, Peter Grabham, Eileen P. Connolly, Debarshi Banerjee
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:E653
Autor:
Douglas K. Marks, Yan Lu, Kevin Kalinsky, Thomas D. Hart, Hanina Hibshoosh, Eileen P. Connolly, Margueritta El Asmar, Yvonne M. Saenger, Camden L Esancy, Shuobo Boboila, Robyn D. Gartrell
Publikováno v:
Journal of Clinical Oncology. 36:12057-12057
12057Background: The PI3K/Akt/mTOR pathway is a known regulator of oncogenic growth in BC. In addition, this pathway also modulates host immune function and may indirectly affect tumorigenesis. Cli...