Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Shunsuke Sakai"'
Autor:
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Joel D Fleegle, Felipe Gomez, NIAID/DIR Tuberculosis Imaging Program, Sydnee T Gould, Cyril Le Nouën, Xueqiao Liu, Tracey L Burdette, Nicole L Garza, Bernard A P Lafont, Kelsie Brooks, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Alessandro Sette, Heather D Hickman, Ursula J Buchholz, Reed F Johnson, Jason M Brenchley, James P Oberman, Artur T L Quieroz, Bruno B Andrade, Laura E Via, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012339 (2024)
The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2 infection is incompletely understood. Here we examine the roles of the prototypic pro- and anti-inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of
Externí odkaz:
https://doaj.org/article/4f2fca22c4d14a298492237eba187e8e
Autor:
Stella G. Hoft, Keith D. Kauffman, Shunsuke Sakai, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Daniel F. Hoft, Richard Herbert, Daniel L. Barber
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Alternative delivery routes of the current Mycobacterium tuberculosis (Mtb) vaccine, intradermally (ID) delivered BCG, may provide better protection against tuberculosis, and be more easily administered. Here, we use rhesus macaques to compa
Externí odkaz:
https://doaj.org/article/0ede394fe9264bd2be150bdaf50800d8
Publikováno v:
Polymers, Vol 15, Iss 23, p 4592 (2023)
With respect to the fossil resources shortage, the development of bio-based wood adhesives is an important research topic in wood science. There has been research on using sucrose for bio-based adhesives. However, a high acid catalyst content and a h
Externí odkaz:
https://doaj.org/article/0e7b7bf9cbaa4a139d08c5212d8048d0
Autor:
Ryohei Kozaki, Tomoko Yasuhiro, Hikaru Kato, Jun Murai, Shingo Hotta, Yuko Ariza, Shunsuke Sakai, Ryu Fujikawa, Takao Yoshida
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282166 (2023)
Tirabrutinib is a highly selective Bruton's tyrosine kinase (BTK) inhibitor used to treat hematological malignancies. We analyzed the anti-tumor mechanism of tirabrutinib using phosphoproteomic and transcriptomic methods. It is important to check the
Externí odkaz:
https://doaj.org/article/ce0a04b154294e48a34fb37c7e65fd46
Autor:
Yuki Nakagomi, Kazuko Tajiri, Saori Shimada, Siqi Li, Keiko Inoue, Yoshiko Murakata, Momoko Murata, Shunsuke Sakai, Kimi Sato, Masaki Ieda
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Immune checkpoint inhibitor (ICI)-related myositis with myocarditis is a rare but potentially fatal immune-related adverse event. However, its clinical features, response to immunosuppressive treatment, and prognosis remain poorly underst
Externí odkaz:
https://doaj.org/article/428586aff07c41c48337d33c23dec0d0
Publikováno v:
Physiological Reports, Vol 8, Iss 22, Pp n/a-n/a (2020)
Abstract After parturition, cows frequently develop uterine bacterial infections, resulting in the onset of endometritis. To eliminate the bacteria, bovine endometrial cells secrete chemokines, such as IL‐6 and MCP1, which attract macrophages (MΦs
Externí odkaz:
https://doaj.org/article/45dc225931cd47db909884bab2e68f97
Autor:
Michelle A. Sallin, Shunsuke Sakai, Keith D. Kauffman, Howard A. Young, Jinfang Zhu, Daniel L. Barber
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3091-3104 (2017)
Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1-polarizing factors in the generation of protective and non-protective subsets of Mtb-sp
Externí odkaz:
https://doaj.org/article/06bfe3aba54549109805dc7c8b3325f5
Autor:
Zhongyuan Zhao, Shunsuke Sakai, Di Wu, Zhen Chen, Nan Zhu, Chengsheng Gui, Min Zhang, Kenji Umemura, Qiang Yong
Publikováno v:
Polymers, Vol 12, Iss 1, p 216 (2020)
In this study, a further investigation was carried out on the synthesis mechanism, optimal manufacturing conditions, and curing behavior of a sucrose-ammonium dihydrogen phosphate (SADP) adhesive. The results of 13C nuclear magnetic resonance (NMR) s
Externí odkaz:
https://doaj.org/article/6b52020281984dc480da1d37fa25aff3
Autor:
Shunsuke Sakai, Keith D Kauffman, Michelle A Sallin, Arlene H Sharpe, Howard A Young, Vitaly V Ganusov, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005667 (2016)
IFN-γ-producing CD4 T cells are required for protection against Mycobacterium tuberculosis (Mtb) infection, but the extent to which IFN-γ contributes to overall CD4 T cell-mediated protection remains unclear. Furthermore, it is not known if increas
Externí odkaz:
https://doaj.org/article/7f77a02e79c44c3fbea7435cc5c4fc21
Publikováno v:
Modern Rheumatology Case Reports; Jul2024, Vol. 8 Issue 2, p310-313, 4p