Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Shunsuke Koga"'
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Shunsuke Koga, Aya Murakami, Alexandra I. Soto-Beasley, Ronald L. Walton, Matthew C. Baker, Monica Castanedes-Casey, Keith A. Josephs, Owen A. Ross, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Frontotemporal lobar degeneration (FTLD) is a group of disorders characterized by degeneration of the frontal and temporal lobes, leading to progressive decline in language, behavior, and motor function. FTLD can be further subdivided into t
Externí odkaz:
https://doaj.org/article/ac89a41380b2423b8c85b9f8a0592b72
Autor:
Shunsuke Koga, Michael A. Metrick, Lawrence I. Golbe, Alessia Santambrogio, Minji Kim, Alexandra I. Soto-Beasley, Ronald L. Walton, Matthew C. Baker, Cristhoper Fernandez De Castro, Michael DeTure, David Russell, Bradford A. Navia, Christine Sandiego, Owen A. Ross, Michele Vendruscolo, Byron Caughey, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are distinct clinicopathological subtypes of frontotemporal lobar degeneration. They both have atypical parkinsonism, and they usually have distinct clinical features.
Externí odkaz:
https://doaj.org/article/5b670a275ffd416fa2fba930681c881b
Autor:
Keith Anthony Josephs, Shunsuke Koga, Nirubol Tosakulwong, Stephen D. Weigand, Nha Trang Thu Pham, Matt Baker, Jennifer L. Whitwell, Rosa Rademakers, Leonard Petrucelli, Dennis W. Dickson
Publikováno v:
Free Neuropathology, Vol 4 (2023)
TAR DNA binding protein 43 (TDP-43) pathology is a defining feature of frontotemporal lobar degeneration (FTLD). In FTLD-TDP there is a moderate-to-high burden of morphologically distinctive TDP-43 immunoreactive inclusions distributed throughout the
Externí odkaz:
https://doaj.org/article/2d46bc8252ce424389373b1fbe98dfdc
Autor:
Hiroaki Sekiya, Asato Tsuji, Yuki Hashimoto, Mariko Takata, Shunsuke Koga, Katsuya Nishida, Naonobu Futamura, Michi Kawamoto, Nobuo Kohara, Dennis W. Dickson, Hisatomo Kowa, Tatsushi Toda
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract The pathological hallmarks of Parkinson’s disease (PD) are α-synuclein (αSYN)-positive inclusions referred to as Lewy bodies and Lewy neurites, collectively referred to as Lewy-related pathology (LRP). LRP is thought to propagate in an a
Externí odkaz:
https://doaj.org/article/4c4ffbf507a846fca4aa61e375060fe2
Autor:
Shunsuke Koga, Wei Du
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 2, Pp 487-488 (2025)
Externí odkaz:
https://doaj.org/article/2e88e8e7230a43daa63de22d2ff79f3d
Autor:
Rebecca R. Valentino, Chloe Ramnarine, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Koji Kasanuki, Melissa E. Murray, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin-Taner, Rodolfo Savica, Jonathan Graff-Radford, Ronald C. Petersen, Joseph E. Parisi, R. Ross Reichard, Neill R. Graff-Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Dementia with Lewy bodies (DLB) is clinically diagnosed when patients develop dementia less than a year after parkinsonism onset. Age is the primary risk factor for DLB and mitochondrial health influences ageing through effective oxidative p
Externí odkaz:
https://doaj.org/article/3ccebbf408344276a4d599bfa2266e82
Autor:
Shunsuke Koga, Mariam Ishaque, W. Jeffrey Elias, Binit B. Shah, Aya Murakami, Dennis W. Dickson
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Focused ultrasound (FUS) thalamotomy is an emerging treatment for tremor-dominant Parkinson’s disease (PD). We report the first postmortem neuropathologic study of FUS thalamotomy in a 68-year-old man with tremor-dominant PD, which was per
Externí odkaz:
https://doaj.org/article/b4217d97eadf4af4857532363d44adc0
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100210- (2023)
Externí odkaz:
https://doaj.org/article/e63a2cdaef2f4c3b8761bffdd34b4c54
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-24 (2021)
Abstract Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the form of Lewy bodies, Lewy neurites, neuronal cytoplasmic inclusions, and glial cyt
Externí odkaz:
https://doaj.org/article/0b3774b9f6cd4463bc1ab744440a1792