Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shunsuke Kanada"'
Autor:
Yoshihiko Usui, Ko Okumura, Hideoki Ogawa, Nao Kitamura, Chiharu Nishiyama, Shunsuke Kanada, Mutsuko Hara, Hokuto Yokoyama, Tomonobu Ito, Kanako Fukuyama, Keiko Maeda, Naomi Shimokawa, Makoto Nishiyama
Publikováno v:
Molecular Immunology. 53:295-301
CD11c, a member of the β(2) integrin family of adhesion molecule, is expressed on the surface of myeloid lineages and activated lymphoid cells and forms a heterodimeric receptor with CD18. We analyzed the mouse CD11c promoter structure to elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8685699eb311a93a005c398dbf5d21e7
https://doi.org/10.1016/j.molimm.2012.08.004
https://doi.org/10.1016/j.molimm.2012.08.004
Autor:
Mutsuko Hara, Chang long Lu, Nobuhiro Nakano, Naomi Shimokawa, Shunsuke Kanada, Chiharu Nishiyama, Ko Okumura, Hideoki Ogawa, Nao Kitamura, Qing hui Wang
Publikováno v:
FEBS Letters. 584:2315-2320
Mast cells (MCs) are activated upon stimulation via TLRs or FcepsilonRI, contributing to immune protection and/or leading to allergic diseases. In the present study, the effects of Trichostatin A (TSA) on the activation of MCs were analyzed with bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db99092578cc5482aad1b3751eb747b
https://doi.org/10.1016/j.febslet.2010.03.047
https://doi.org/10.1016/j.febslet.2010.03.047
Autor:
Chiharu Nishiyama, Nobuhiro Nakano, Mutsuko Hara, Shunsuke Kanada, Ko Okumura, Tatsuo Fukai, Keiko Maeda, Tomoko Tokura, Ewa Stępień, Daniel P. Potaczek, Qing hui Wang, Agnieszka Branicka, Hideoki Ogawa, Anetta Undas
Publikováno v:
Immunogenetics. 61:649-655
Three frequent genetic polymorphisms in the human high-affinity IgE receptor α-subunit (FceRIα) were shown to be associated with allergic disorders and/or total serum IgE levels in allergic patients. Two of these were previously demonstrated to aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853a2c5716b1ed922d8bcb031cf0bb47
https://doi.org/10.1007/s00251-009-0391-x
https://doi.org/10.1007/s00251-009-0391-x
Autor:
Yoshihiko Usui, Ryoji Tsuboi, Ko Okumura, Hisaya Akiba, Mutsuko Hara, Shunsuke Kanada, Chiharu Nishiyama, Nobuhiro Nakano, Kazuyoshi Takeda, Hideoki Ogawa, Tomoko Tokura, Kanako Fukuyama, Tomonobu Ito, Makoto Nishiyama
Publikováno v:
International Immunology. 21:803-816
Over-expression of PU.1, a myeloid- and lymphoid-specific transcription factor belonging to the Ets family, induces monocyte-specific gene expression in mast cells. However, the effects of PU.1 on each target gene and the involvement of cytokine sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2136a9bbac3c115c80f04efae2014b
https://doi.org/10.1093/intimm/dxp048
https://doi.org/10.1093/intimm/dxp048
Autor:
Shunsuke Kanada, Ko Okumura, Hideoki Ogawa, Nobuhiro Nakano, Chiharu Nishiyama, Naomi Shimokawa, Qing Hui Wang, Mutsuko Hara
Publikováno v:
Immunogenetics. 60:557-563
The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, is specifically expressed in mast cells and basophils and plays a key role in IgE-mediated allergic reactions. The transcription factor Elf-1 has been previously identified to bind t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4539ee0aa5fb3f9da348220a44158d
https://doi.org/10.1007/s00251-008-0318-y
https://doi.org/10.1007/s00251-008-0318-y
Autor:
Nobuhiro Nakano, Ko Okumura, Chiharu Nishiyama, Andrzej Szczeklik, Naomi Shimokawa, Tatsuo Fukai, Hideo Yagita, Keiko Maeda, Shunsuke Kanada, Marek Sanak, Hideoki Ogawa, Yusuke Niwa, Daniel P. Potaczek
Publikováno v:
The Journal of Immunology. 180:8204-8210
The α-chain is a specific component of FcεRI, which is essential for the cell surface expression of FcεRI and the binding of IgE. Recently, two single nucleotide polymorphisms (SNPs) in the α-chain promoter, −315C>T and −66T>C, have been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c69b10269ad95481acf98301f659582
https://doi.org/10.4049/jimmunol.180.12.8204
https://doi.org/10.4049/jimmunol.180.12.8204
Autor:
Nobuyasu Mayuzumi, Shunsuke Kanada, Hideoki Ogawa, Keiko Maeda, Nobuhiro Nakano, Shigaku Ikeda, Hiroshi Kawada, Tomoko Tokura, Atsushi Takagi, Ko Okumura, Makoto Nishiyama, Chiharu Nishiyama, Yusuke Niwa
Publikováno v:
Journal of Investigative Dermatology. 128:96-103
The ATP2A2 gene encodes Ca2+-dependent ATPase, the dysfunction of which causes Darier disease. In this study, we analyzed the promoter structure of the human ATP2A2 gene using primary normal human keratinocytes (NHK). Reporter assays showed that dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42958de993d1c0f03f90c5149d7c4ec5
https://doi.org/10.1038/sj.jid.5700937
https://doi.org/10.1038/sj.jid.5700937
Autor:
Hideoki Ogawa, Atsushi Takagi, Chiharu Nishiyama, Ko Okumura, Shigaku Ikeda, Shunsuke Kanada, Yusuke Niwa, Kanako Fukuyama
Publikováno v:
Biochemical and Biophysical Research Communications. 347:388-393
A transcriptional cofactor, the MHC class II transactivator (CIITA), is a master regulator of MHC class II gene expression. CIITA expression is restricted in MHC class II-positive cells and is regulated by 4 (human) or 3 (mouse) promoters. To clarify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b044e77d3166733da30eb510f455379
https://doi.org/10.1016/j.bbrc.2006.05.215
https://doi.org/10.1016/j.bbrc.2006.05.215
Autor:
Hideoki Ogawa, Tomoko Tokura, Keiko Maeda, Shunsuke Kanada, Ko Okumura, Makoto Nishiyama, Chiharu Nishiyama, Hiroyasu Nakano
Publikováno v:
Blood. 108:262-269
Cell-type-specific transcription of mouse high-affinity IgE receptor (FcepsilonRI) beta-chain is positively regulated by the transcription factor GATA-1. Although GATA-1 is expressed in erythroid cells, megakaryocytes, and mast cells, the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cce0a6124a307a76bff1db0cc5bd5a
https://doi.org/10.1182/blood-2005-07-2878
https://doi.org/10.1182/blood-2005-07-2878
Autor:
Tomonobu Ito, Hideoki Ogawa, Chiharu Nishiyama, Yusuke Niwa, Mami Tajima, W. Ng, Naomi Shimokawa, Shunsuke Kanada, S. Ikeda, Ayako Hobo, Kouichi Mitsuishi, Atsushi Takagi, Ko Okumura, Daniel P. Potaczek, Ryoji Tsuboi, Yukari Okubo
Publikováno v:
International Journal of Immunogenetics. 37:139-141
Two promoter polymorphisms of the high-affinity IgE receptor alpha-subunit (FcepsilonRIalpha) gene (FCER1A), -66T>C (rs2251746) and -315C>T (rs2427827), were analysed in Japanese atopic dermatitis subjects. Patients with the -315CT/TT genotype tended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92d27e6cf2f562c41958e653492426e
https://doi.org/10.1111/j.1744-313x.2010.00901.x
https://doi.org/10.1111/j.1744-313x.2010.00901.x