Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shunsuke Iriyama"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The epidermal basement membrane deteriorates with aging. We previously reported that basement membrane reconstruction not only serves to maintain epidermal stem/progenitor cells in the epidermis, but also increases collagen fibrils in the pa
Externí odkaz:
https://doaj.org/article/a9c648a05dff48fcbfd70c9b7d4666fb
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reports
Scientific Reports
The epidermal basement membrane deteriorates with aging. We previously reported that basement membrane reconstruction not only serves to maintain epidermal stem/progenitor cells in the epidermis, but also increases collagen fibers in the papillary de
Publikováno v:
The American Journal of Pathology. 191:1010-1019
Hyaluronan (HA) is the major glycosaminoglycan in the extracellular matrix of most mammalian tissues, including the epidermis. It is synthesized in epidermis, and mainly metabolized after transfer to the liver via lymphatic vessels in the dermis foll
Autor:
Gangwen Han, Shunsuke Iriyama, Bin Fan, Zhe Jian, Li Bian, Dongyan D. Wang, Christian D. Young, Fulun Li, Xiao-Jing Wang, Jingjing Luo
Publikováno v:
Journal of Investigative Dermatology. 139:940-950
We assessed the roles of Smad7 in skin inflammation and wound healing using genetic and pharmacological approaches. In K5.TGFβ1/K5.Smad7 bigenic (double transgenic) mice, Smad7 transgene expression reversed transforming growth factor (TGF)-β1 trans
Publikováno v:
Experimental Dermatology. 28:247-253
Daily exposure to sunlight is known to affect the structure and function of the epidermal basement membrane (BM), as well as epidermal differentiation and epidermal barrier function. The aim of this study is to clarify whether the inhibition of BM-de
Autor:
Junichi Hosoi, Eisuke Takai, Saori Nishikawa, Satoshi Amano, Shunsuke Iriyama, Masahito Yasuda
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Daily sunlight exposure damages the epidermal basement membrane (BM) and disrupts epidermal homeostasis. Inter-follicular epidermal stem cells (IFE-SCs) regulate epidermal proliferation and differentiation, which supports epidermal homeostasis. Here,
Publikováno v:
Journal of dermatological science. 91(1)
Publikováno v:
Journal of Investigative Dermatology. 139:S251
Publikováno v:
Journal of Dermatological Science. 64:223-228
Background Skin pigmentation induced by ultraviolet B radiation is caused in part by inflammation mediated by cytokines secreted from keratinocytes and fibroblasts in the irradiated area. Heparanase is also activated in the irradiated skin, and this