Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shunsuke Ima"'
Autor:
Shun Kaneko, Shunsuke Imai, Tomomi Uchikubo-Kamo, Tamao Hisano, Nobuaki Asao, Mikako Shirouzu, Ichio Shimada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract G-protein-coupled receptors (GPCRs) play pivotal roles in various physiological processes. These receptors are activated to different extents by diverse orthosteric ligands and allosteric modulators. However, the mechanisms underlying these
Externí odkaz:
https://doaj.org/article/8986cdcaf6aa480fa00140791f388d6f
Autor:
Yuri Nishioka, Yasunori Matsumoto, Shunsuke Imanishi, Satoshi Endo, Takeshi Toyozumi, Yoshihiro Kurata, Takuma Sasaki, Gaku Ohira, Koichi Hayano, Hisahiro Matsubara
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Background Small bowel cancer is very rare, accounting for less than 5% of all gastrointestinal cancers, and small bowel adenocarcinoma accounts for approximately 40% of all small bowel cancers. Small bowel adenocarcinoma is often found in a
Externí odkaz:
https://doaj.org/article/b3751fd3412e409f9e082e66fb63fb08
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Many RNA viruses employ internal ribosome entry sites (IRESs) in their genomic RNA to commandeer the host’s translational machinery for replication. The IRES from encephalomyocarditis virus (EMCV) interacts with eukaryotic translation init
Externí odkaz:
https://doaj.org/article/78178287e2944361b00c4f2ec6822014
Autor:
Ryosuke Murai, Keisuke Kida, Hiroshi Suzuki, Yasushi Sakata, Takayuki Ise, Shin-ichiro Miura, HIROKAZU KONDO, Yuichi Tamura, Misato Chimura, Tatsunori Taniguchi, Kensuke Takabayashi, Shinji Koba, Hiroyuki Miura, Emi Maekawa, Koki Matsuo, Wataru Fujimoto, Shunsuke Imai, Hideki Origuchi, Akiko Goda, Ryotaro Saita, Atsushi Kikuchi
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Cardiac rehabilitation (CR) is strongly recommended as a medical treatment to improve the prognosis and quality of life of patients with heart failure (HF); however, participation rates in CR are low compared with other evidence-based tr
Externí odkaz:
https://doaj.org/article/f7e6450e596e4ed088c8e628c4bcd1c3
Autor:
Hideaki Ota, Hitoshi Matsuo, Shunsuke Imai, Yuki Nakashima, Yoshiaki Kawase, Munenori Okubo, Hiroshi Takahashi, Hideki Kawai, Yoshihiro Sobue, Masanori Kawasaki, Takeshi Kondo, Takashi Muramatsu, Hideo Izawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundThis study compares the efficacy of coronary computed tomography angiography (CCTA) and near-infrared spectroscopy intravascular ultrasound (NIRS–IVUS) in patients with significant coronary stenosis for predicting periprocedural myocardia
Externí odkaz:
https://doaj.org/article/9f02279eb8bf4070840438998582baba
Autor:
Noda T, Y Kiyozuka, Michiaki Yakushiji, Nishimura H, Tomohiko Matsuyama, Yoshihiro Teramoto, Shunsuke Ima, F Murakami, K Imamura
Publikováno v:
The Journal of the Japanese Society of Clinical Cytology. 33:620-627
We present the eighth case of a neuroblastoma to present clinically as a primary ovarian cancer, and the third to be confirmed as a malignant transformation of a mature cystic teratoma of the ovary. Histological sections of the ovarian mass obtained
Autor:
Kazuki Matsumura, Takushi Shimomura, Yoshihiro Kubo, Takayuki Oka, Naohiro Kobayashi, Shunsuke Imai, Naomi Yanase, Madoka Akimoto, Masahiro Fukuda, Mariko Yokogawa, Kazuyoshi Ikeda, Jun-ichi Kurita, Yoshifumi Nishimura, Ichio Shimada, Masanori Osawa
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Human ether-à-go-go-related gene potassium channel 1 (hERG) is a voltage-gated potassium channel, the voltage-sensing domain (VSD) of which is targeted by a gating-modifier toxin, APETx1. APETx1 is a 42-residue peptide toxin of s
Externí odkaz:
https://doaj.org/article/fefcd79f84134514b7e6ed26583065d2
Autor:
Yuta Iwahashi, Yuki Toyama, Shunsuke Imai, Hiroaki Itoh, Masanori Osawa, Masayuki Inoue, Ichio Shimada
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Potassium ion channels control K+ permeation across cell membranes and mutations that cause cardiovascular and neural diseases are known. Here, the authors perform NMR measurements with the prototypical K+ channel from Streptomyces lividans, KcsA and
Externí odkaz:
https://doaj.org/article/1e91ff52d72149278985a050c03132cb
Autor:
Hanaho Kano, Yuki Toyama, Shunsuke Imai, Yuta Iwahashi, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Opening of G protein-gated inwardly rectifying potassium channels (GIRK) is coupled to the activation of a GPCR. Here the authors use NMR and cell-based BRET assays to gain insights into the mechanisms underlying family-specific activation and find t
Externí odkaz:
https://doaj.org/article/1d3c5f17ee3f414881ec083bebb5692c
Autor:
Gaku Ohira, Hideaki Miyauchi, Koichi Hayano, Shunsuke Imanishi, Toru Tochigi, Tetsuro Maruyama, Toshiharu Hanaoka, Koichiro Okada, Hiroki Kobayashi, Takashi Uno, Hisahiro Matsubara
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 3, Iss 1, Pp 43-48 (2019)
Objectives: To clarify the safety and efficacy of celecoxib combined with chemoradiotherapy using S-1 for lower rectal cancer. Methods: Twenty-one patients with pathologically proven lower rectal adenocarcinoma (cT3-T4, Tx N+, M0) were included in th
Externí odkaz:
https://doaj.org/article/a1ae9a1dd54e4897b700045a9a05a412