Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shunshi Kohyama"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recently, utilization of Machine Learning (ML) has led to astonishing progress in computational protein design, bringing into reach the targeted engineering of proteins for industrial and biomedical applications. However, the design of prote
Externí odkaz:
https://doaj.org/article/7615e1ee231d49e5b6275ae1876afd03
Autor:
Saki Nishikawa, Gaku Sato, Sakura Takada, Shunshi Kohyama, Gen Honda, Miho Yanagisawa, Yutaka Hori, Nobuhide Doi, Natsuhiko Yoshinaga, Kei Fujiwara
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Cells are small, closed spaces filled with various types of macromolecules. Although it is shown that the characteristics of biochemical reactions in vitro are quite different from those in living cells, the role of the co‐existence of var
Externí odkaz:
https://doaj.org/article/f1fe95f794bb4244bc6b0b8052d83b5d
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Externí odkaz:
https://doaj.org/article/900b1408285d4f4bacd6bc6c0b667e6c
Publikováno v:
Bio-Protocol, Vol 10, Iss 6 (2020)
The Min system determines the cell division plane of bacteria. As a cue of spatiotemporal regulation, the Min system uses wave propagation of MinD protein (Min wave). Therefore, the reconstitution of the Min wave in cell-sized closed space will lead
Externí odkaz:
https://doaj.org/article/c368e1e3f37a4017aaacd61d4af2764a
Publikováno v:
eLife, Vol 8 (2019)
The Min system, a system that determines the bacterial cell division plane, uses changes in the localization of proteins (a Min wave) that emerges by reaction-diffusion coupling. Although previous studies have shown that space sizes and boundaries mo
Externí odkaz:
https://doaj.org/article/e4c8503423f14afdb22190a7e504b9b3
Recently, utilization of machine learning (ML) based methods has led to astonishing progress in protein design and, thus, the design of new biological functionality. However, emergent functions that require higher-order molecular interactions, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34620e41dbcc1d1e5c8e42668ffe96cd
https://doi.org/10.1101/2023.02.16.528840
https://doi.org/10.1101/2023.02.16.528840
Constructing a minimal machinery for autonomous self-division of synthetic cells is a major goal of bottom-up synthetic biology. One paradigm has been the E. coli divisome, with the MinCDE protein system guiding assembly and positioning of a presumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0612af26714d42d9324b789bcdb2ac7f
https://doi.org/10.21203/rs.3.rs-1284300/v1
https://doi.org/10.21203/rs.3.rs-1284300/v1
Publikováno v:
Chemical Science. 10:11064-11072
Spatiotemporal patterning is a fundamental mechanism for developmental differentiation and homeostasis in living cells. Because spatiotemporal patterns are based on higher-order collective motions of elements synthesized from genes, their behavior dy
Autor:
Anna M. Wagner, Hiromune Eto, Anton Joseph, Shunshi Kohyama, Tamás Haraszti, Ricardo A. Zamora, Mariia Vorobii, Marina I. Giannotti, Petra Schwille, Cesar Rodriguez‐Emmenegger
Publikováno v:
Advanced Materials. 34:2270212
Publikováno v:
Nanoscale. 12(22)
The Min system for determining the cell division position at the center in bacteria has a unique character that uses a protein wave (Min wave) that emerges from its components (MinD and MinE). The Min wave emerges under the coupling of chemical react