Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Shunsei, Hirohata"'
Autor:
Shunsei Hirohata, Hirotoshi Kikuchi
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 1, Pp 42-49 (2021)
Objective The present study was designed in order to elucidate the roles of serum interleukin 6 (IL‐6) in the pathogenesis in neuropsychiatric systemic lupus erythematosus (NPSLE). Methods Paired serum and cerebrospinal fluid (CSF) samples were obt
Externí odkaz:
https://doaj.org/article/ec666edafacd4bca8eeca376cefc96cf
Autor:
Shunsei Hirohata, Hirotoshi Kikuchi, Tetsuji Sawada, Masataka Kuwana, Izumi Kawachi, Yohei Kirino, Yoshiaki Ishigatsubo, Mitsuhiro Takeno
Publikováno v:
Internal Medicine; 2024, Vol. 63 Issue 4, p481-486, 6p
Autor:
Toshihiro Tono, Satoko Aihara, Takayuki Hoshiyama, Yoshiyuki Arinuma, Tatsuo Nagai, Shunsei Hirohata
Publikováno v:
Inflammation and Regeneration, Vol 37, Iss 1, Pp 1-6 (2017)
Abstract Background Abatacept, a CTLA4-Ig fusion protein attenuates T cell activation by inhibiting the CD80/86-CD28 costimulatory pathway that is required for the proper T cell activation and thus displays beneficial effects in the treatment of rheu
Externí odkaz:
https://doaj.org/article/b0de17aae348438480976dffb202ebfd
Autor:
Hiroko Nagafuchi, Hirotoshi Kikuchi, Hiroyuki Ishibash, Hideaki Maeda, Hitoshi Ogino, Yohei Kirino, Tetsuji Sawada, Kazuyoshi Saito, Masataka Kuwana, Shunsei Hirohata, Yoshiaki Ishigatsubo, Masanori Niimi, Yutaka Okita, Tetsuro Miyata, Hiroshi Shigematsu, Mitsuhiro Takeno
Publikováno v:
Modern Rheumatology.
Objectives This study aimed to develop clinical guidelines for the management of vascular Behçet’s disease (BD) by the Behçet’s Disease Research Committee of the Ministry of Health, Labour and Welfare of the Japanese Government. Methods A task
Autor:
Yohei Kirino, Toshihiro Tono, Hirotoshi Kikuchi, Shunsei Hirohata, Mitsuhiro Takeno, Tetsuji Sawada, Yoshiya Tanaka, Kunihiro Yamaoka, Hiroko Nagafuchi
Publikováno v:
Modern Rheumatology. 32:1146-1152
Objectives Approximately 30–60% of Behçet’s disease patients exhibit joint symptoms. The aim of this study was to determine the clinical characteristics of such patients in Japan. Methods This study retrospectively analyzed 151 Behçet’s disea
Autor:
Guido Alves, Shunsei Hirohata, Lasse G. Gøransson, Erna Harboe, Anne Bolette Tjensvoll, Roald Omdal, Jan Terje Kvaløy, Ingeborg Kvivik, Ole Jacob Greve, Maria B. Lauvsnes, Mona K. Beyer, Kaj Blennow, Stian Maroni, Henrik Zetterberg
Publikováno v:
Journal of Neurology. 269:3064-3074
Neuropsychiatric manifestations (NP) are common in systemic lupus erythematosus (SLE). However, the pathophysiological mechanisms are not completely understood. Neurofilament light protein (NfL) is part of the neuronal cytoskeleton. Increased NfL con
Autor:
Kazuma Ino, Yoshiyuki Arinuma, Yoshiro Kanayama, Kenji Oku, Kunihiro Yamaoka, Shunsei Hirohata, Yu Matsueda, Junichi Kondo, Takuya Isayama, Takumi Muramatsu, Yasuhiro Hasegawa
Publikováno v:
International Journal of Rheumatic Diseases. 25:70-75
AIM Anti-ribosomal P protein antibodies (anti-ribo P) have been reported as one of the specific autoantibodies in patients with systemic lupus erythematosus (SLE) and has been demonstrated to bind and activate macrophages in vitro. Clinically, hyperf
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209282 (2018)
The present study was performed to elucidate the roles of serum anti-Sm antibodies in the pathogenesis of systemic lupus erythematosus (SLE). Highly purified peripheral blood monocytes obtained from healthy donors were cultured in the presence of mon
Externí odkaz:
https://doaj.org/article/bafc93b2edba4602b0ef0e6431272b0a
Autor:
Tomoyuki Asano, Hiromi Ito, Yoshinobu Kariya, Kyoka Hoshi, Akioh Yoshihara, Yoshikazu Ugawa, Hideharu Sekine, Shunsei Hirohata, Yoshiki Yamaguchi, Shuzo Sato, Hiroko Kobayashi, Kiyoshi Migita, Hiromasa Ohira, Yasuhiro Hashimoto, Hiroshi Watanabe
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186414 (2017)
Although quotient of alpha2 macroglobulin (Qα2MG) was previously reported to be useful for the evaluation of blood-brain barrier (BBB) function, it is not commonly used. We therefore evaluated BBB function among the various subsets of neuropsychiatr
Externí odkaz:
https://doaj.org/article/e6d07c93e8ba4fbdb37b190c50aba7f7
Autor:
Shunsei, Hirohata
Publikováno v:
Arerugi = [Allergy]. 71(3)