Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Shunsaku Takayanagi"'
Autor:
Takenori Shimizu, Shota Tanaka, Yosuke Kitagawa, Yusuke Sakaguchi, Mako Kamiya, Shunsaku Takayanagi, Hirokazu Takami, Yasuteru Urano, Nobuhito Saito
Publikováno v:
Frontiers in Surgery, Vol 11 (2024)
Surgical resection is considered for most brain tumors to obtain tissue diagnosis and to eradicate or debulk the tumor. Glioma, the most common primary malignant brain tumor, generally has a poor prognosis despite the multidisciplinary treatments wit
Externí odkaz:
https://doaj.org/article/e04246f87365474b96dcadc8e7a7535d
Autor:
Yu Teranishi, Satoru Miyawaki, Masahiro Nakatochi, Atsushi Okano, Kenta Ohara, Hiroki Hongo, Daiichiro Ishigami, Yu Sakai, Daisuke Shimada, Shunsaku Takayanagi, Masako Ikemura, Daisuke Komura, Hiroto Katoh, Jun Mitsui, Shinichi Morishita, Tetsuo Ushiku, Shumpei Ishikawa, Hirofumi Nakatomi, Nobuhito Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Although recent molecular analyses revealed that sporadic meningiomas have various genetic, epigenetic, and transcriptomic profiles, meningioma in patients with neurofibromatosis type 2 (NF2) have not been fully elucidated. This study invest
Externí odkaz:
https://doaj.org/article/36132233814845119abf3aa8a2f37537
Autor:
Daisuke Sato, Hirokazu Takami, Shunsaku Takayanagi, Kazuki Taoka, Mariko Tanaka, Reiko Matsuura, Shota Tanaka, Nobuhito Saito
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Lymphoproliferative disorder represents a heterogeneous clinicopathological spectrum characterized by uncontrolled proliferation of lymphocytes. Immunodeficiency is a major trigger of its development. While induction of immunodefi
Externí odkaz:
https://doaj.org/article/072133ba60874fe0ac7948a0aa4d0689
Autor:
Yoshihiro Kushihara, Shota Tanaka, Yukari Kobayashi, Koji Nagaoka, Miyu Kikuchi, Takahide Nejo, Erika Yamazawa, Shohei Nambu, Kazuha Kugasawa, Hirokazu Takami, Shunsaku Takayanagi, Nobuhito Saito, Kazuhiro Kakimi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundGlioblastoma (GBM) is a highly lethal brain tumor. The effectiveness of temozolomide (TMZ) treatment in GBM is linked to the methylation status of O6-methyl-guanine DNA methyltransferase (MGMT) promoter. Patients with unmethylated MGMT prom
Externí odkaz:
https://doaj.org/article/ca6009eeb817459d85daa3d3d501a4ee
Autor:
Kenta Ohara, Satoru Miyawaki, Hirofumi Nakatomi, Atsushi Okano, Yu Teranishi, Yuki Shinya, Daiichiro Ishigami, Hiroki Hongo, Shunsaku Takayanagi, Shota Tanaka, Aya Shinozaki-Ushiku, Shinji Kohsaka, Hidenori Kage, Katsutoshi Oda, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano, Kenji Tatsuno, Nobuhito Saito
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundDespite accumulating research on the molecular characteristics of meningiomas, no definitive molecularly targeted therapy for these tumors has been established to date. Molecular mechanisms underlying meningioma progression also remain uncl
Externí odkaz:
https://doaj.org/article/d859c4bf55e04b03bc551a5a2e9a002d
Autor:
Yudai Hirano, Yuki Shinya, Toshiya Aono, Hirotaka Hasegawa, Mariko Kawashima, Masahiro Shin, Hirokazu Takami, Shunsaku Takayanagi, Motoyuki Umekawa, Masako Ikemura, Tetsuo Ushiku, Kazuki Taoka, Shota Tanaka, Nobuhito Saito
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4558-4565 (2022)
Stereotactic frame-based brain tumor biopsy (SFB) is a potent diagnostic tool considering its minimal invasiveness, though its diagnostic power and safety for brainstem lesions remain to be discussed. Here, we aimed to examine the usefulness of SFB f
Externí odkaz:
https://doaj.org/article/ade42be5c2904ecd818410cd38103dbf
Autor:
Yu Teranishi, Satoru Miyawaki, Hirofumi Nakatomi, Kenta Ohara, Hiroki Hongo, Shogo Dofuku, Atsushi Okano, Shunsaku Takayanagi, Takahiro Ota, Jun Yoshimura, Wei Qu, Jun Mitsui, Shinichi Morishita, Shoji Tsuji, Nobuhito Saito
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Regardless of treatment, the clinical progression of neurofibromatosis type 2 (NF2), particularly in terms of hearing, swallowing, and gait, tend to worsen throughout the patients’ lives. We performed a retrospective analysis of functional
Externí odkaz:
https://doaj.org/article/b4cd5d8b55d44e8caec8a34f5cf339e3
Autor:
Ako Matsuhashi, Shota Tanaka, Hirokazu Takami, Masashi Nomura, Masako Ikemura, Yoshitaka Matsubayashi, Yusuke Shinoda, Keisuke Yamada, Yu Sakai, Yasuaki Karasawa, Shunsaku Takayanagi, Nobuhito Saito
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGlioblastoma is a malignant tumor, and its prognosis is as poor as 1.5 to 2 years. Most cases recur within one year even under the standard treatment. The majority of recurrences are local, and in rare cases, metastasize mostly within the c
Externí odkaz:
https://doaj.org/article/a030dc3b61834d3bb50573acba60efec
Autor:
Daiichiro Ishigami, Satoru Miyawaki, Hirofumi Nakatomi, Shunsaku Takayanagi, Yu Teranishi, Kenta Ohara, Hiroki Hongo, Shogo Dofuku, Taichi Kin, Hiroyuki Abe, Jun Mitsui, Daisuke Komura, Hiroto Katoh, Shumpei Ishikawa, Nobuhito Saito
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Schwannomas are neoplasms that typically arise from the myelin sheath of peripheral nerves and rarely originate within the brain parenchyma. Some case reports present schwannomas arising from the brainstem, but regrowth of the tum
Externí odkaz:
https://doaj.org/article/446c385dac9a43cba98d529b3be0dd7d
Autor:
Takahide Nejo, Shunsaku Takayanagi, Shota Tanaka, Aya Shinozaki-Ushiku, Shinji Kohsaka, Keisuke Nagata, Munehiro Yokoyama, Shigeo Sora, Tetsuo Ushiku, Akitake Mukasa, Hiroyuki Aburatani, Hiroyuki Mano, Nobuhito Saito
Publikováno v:
Clinical Medicine Insights: Case Reports, Vol 15 (2022)
Primary intracranial spindle cell sarcoma is an extremely rare mesenchymal tumor, the molecular pathogenesis of which is poorly understood. Because of the lack of specific markers, diagnosis sometimes relies on ruling out all possible differential di
Externí odkaz:
https://doaj.org/article/16967dd3d62f42a988ec81965fe0cf84