Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Shunli Fu"'
Autor:
Jinhu Liu, Huajun Zhao, Tong Gao, Xinyan Huang, Shujun Liu, Meichen Liu, Weiwei Mu, Shuang Liang, Shunli Fu, Shijun Yuan, Qinglin Yang, Panpan Gu, Nan Li, Qingping Ma, Jie Liu, Xinke Zhang, Na Zhang, Yongjun Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cytotherapy is a strategy to deliver modified cells to a diseased tissue, but targeting solid tumours remains challenging. Here we design macrophages, harbouring a surface glypican-3-targeting peptide and carrying a cargo to combat solid tum
Externí odkaz:
https://doaj.org/article/e0f6524a4aa747788c8e0d90890f216b
Autor:
Huizhen Yang, Weiwei Mu, Shijun Yuan, Han Yang, Lili Chang, Xiao Sang, Tong Gao, Shuang Liang, Xiaoqing Liu, Shunli Fu, Zipeng Zhang, Yongjun Liu, Na Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Immune checkpoint inhibitors (ICIs) combined with antiangiogenic therapy have shown encouraging clinical benefits for the treatment of unresectable or metastatic hepatocellular carcinoma (HCC). Nevertheless, therapeutic efficacy and wide cli
Externí odkaz:
https://doaj.org/article/42ed710dee35490caf73fdc1ad5e65a0
Autor:
Tong Gao, Shijun Yuan, Shuang Liang, Xinyan Huang, Jinhu Liu, Panpan Gu, Shunli Fu, Na Zhang, Yongjun Liu
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Effective presentation of antigens by dendritic cells (DC) is essential for achieving a robust cytotoxic T lymphocytes (CTLs) response, in which cDC1 is the key DC subtype for high‐performance activation of CTLs. However, low cDC1 proporti
Externí odkaz:
https://doaj.org/article/37e13b32094046abbd55266a1ad2f03d
Nano‐Regulator Inhibits Tumor Immune Escape via the 'Two‐Way Regulation' Epigenetic Therapy Strategy
Autor:
Shuang Liang, Meichen Liu, Weiwei Mu, Tong Gao, Shuying Gao, Shunli Fu, Shijun Yuan, Jinhu Liu, Yongjun Liu, Dandan Jiang, Na Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Tumor immune escape caused by low levels of tumor immunogenicity and immune checkpoint‐dependent suppression limits the immunotherapeutic effect. Herein, a “two‐way regulation” epigenetic therapeutic strategy is proposed using a nove
Externí odkaz:
https://doaj.org/article/9e2c282fed074761a5f80200edac5908
Publikováno v:
Nano-Micro Letters, Vol 15, Iss 1, Pp 1-35 (2023)
Highlights The physiological structure and the drug delivery barriers of lymph nodes were described. The factors affecting lymph nodes accumulation in nano-delivery systems were discussed. The recent progress of nano-delivery carriers applied for lym
Externí odkaz:
https://doaj.org/article/a2ada3a8cdf44b84959dcc2b4cfe697b
Autor:
Shunli Fu, Lili Chang, Shujun Liu, Tong Gao, Xiao Sang, Zipeng Zhang, Weiwei Mu, Xiaoqing Liu, Shuang Liang, Han Yang, Huizhen Yang, Qingping Ma, Yongjun Liu, Na Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Targeting tumour immunosuppressive microenvironment is a crucial strategy in immunotherapy. However, the critical role of the tumour lymph node (LN) immune microenvironment (TLIME) in the tumour immune homoeostasis is often ignored. Here, we
Externí odkaz:
https://doaj.org/article/088ad66e83394e9da269425f4225324a
Autor:
Xiaoqing Liu, Shuang Liang, Xiao Sang, Lili Chang, Shunli Fu, Han Yang, Huizhen Yang, Yongjun Liu, Na Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1740-1754 (2023)
Cancer immunotherapy has become a promising strategy. However, the effectiveness of immunotherapy is restricted in “cold tumors” characterized with insufficient T cells intratumoral infiltration and failed T cells priming. Herein, an on-demand in
Externí odkaz:
https://doaj.org/article/9e4ad72a5e0e4c6daf2a4e21e886158c
Publikováno v:
ChemPhysMater, Vol 2, Iss 2, Pp 114-125 (2023)
Micro/nanomotors (MNMs) are small-scale devices that can effectively convert various forms of energy into mechanical motion. Their controllable motility and good permeability have attracted the interest of researchers as promising drug carriers in ca
Externí odkaz:
https://doaj.org/article/ec5230e358874093a8250b95c10bc5b7
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2770 (2023)
Nano-delivery systems have demonstrated great promise in the therapy of cancer. However, the therapeutic efficacy of conventional nanomedicines is hindered by the clearance of the blood circulation system and the physiological barriers surrounding th
Externí odkaz:
https://doaj.org/article/13fa9f9f76e046fc950badc6dafc81d7
Autor:
Shunli Fu, Shuang Liang, Dandan Jiang, Rui Yang, Zipeng Zhang, Lili Chang, Xinke Zhang, Yongjun Liu, Na Zhang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 2, Pp 192-202 (2021)
To improve therapeutic effect and reduce severely side effects of carboplatin (CBP), the gas-generating nanocapsules were developed to accelerate CBP lysosome release and nucleus delivery. CBP/SB-NC was prepared by co-loading CBP and NaHCO3 (SB) in n
Externí odkaz:
https://doaj.org/article/9cd6ceaac24e4aa8b38bb0ea8f863f88