Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shunji Sakuraba"'
Autor:
Yuichi Sugimoto, Koji Yamada, Shinnosuke Abe, Ikuko Nishimura, Hajime Morishima, Hiroki Sato, Hideaki Imamura, Shigeru Nakajima, Aya Shimizu, Shunji Sakuraba, Keiko Miura
Publikováno v:
Tetrahedron. 56:7705-7713
An ultra-broad spectrum carbapenem, J-114,870 (1), was synthesized from the corresponding C-2 side chain and 1β-methylcarbapenem enolphosphate. Synthesis of the C-2 side chain was accomplished by installation of the benzene part to (4R)-hydroxy-2-py
Autor:
Shunji Sakuraba, Yuichi Sugimoto, Hiroki Sakoh, Hideaki Imamura, Hideki Jona, Hajime Morishima, Koji Yamada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 52:992-994
The development of an efficient synthetic method enabled multi-gram synthesis of a key intermediate, which is useful for the modification at the C6-functional group of galbonolide analogues. The structure of a key intermediate including a conjugated
Autor:
Kazuo Achiwa, Shunji Sakuraba
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:748-753
N-(Methylcarbamoyl)-4-(dicyclohexylphosphino)-2-[(diphenylphosphino)methyl]pyrrolidine (MCCPM)- and N-(tert-butoxycarbonyl)-4-(dicyclohexylphosphino)-2-[(diphenylphosphino)methyl]pyrrolidine (BCPM)-rhodium(I) complexes were efficient catalysts for as
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:927-934
A series of (β-N-sulfonylaminoalkyl)phosphine ligands has been developed and employed for asymmetric palladium-catalyzed hydrosilylation and Heck-type hydroarylation, affording up to 72% ee and 90% yield.
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:738-747
The complexes of pyrrolidine bisphosphine ligands (CPMs) with rhodium (I) were found to be efficient catalysts for asymmetric hydrogenation of α-amino ketone hydrochloride derivatives. Utilizing this methodology, we have developed efficient asymmetr
Publikováno v:
Tetrahedron: Asymmetry. 4:1457-1460
A synthetic route to optically active eprozinol has been developed by efficient asymmetric hydrogenations of α- and β-amino ketone hydrochloride derivatives with MCCPM-rhodium catalyst.
Autor:
Masaaki Hirose, Koji Yamada, Hajime Morishima, Shunji Sakuraba, Takashi Hashihayata, Hideaki Imamura, Yuichi Sugimoto, Hiroki Sakoh, Yasuhiro Goto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1500-1502
Improved synthesis of the trans-3,5-disubstituted pyrrolidin-3-ylthio side-chain of the novel carbapenem 1 was achieved via stereoselective reduction of the 1-aryl-1-butanone derivative 5 and successive intramolecular cyclization of the resulting chi
Publikováno v:
ChemInform. 23
Publikováno v:
ChemInform. 26
Publikováno v:
ChemInform. 26