Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shunji Murata"'
Publikováno v:
Japanese Journal of Pharmacology. 72:9-15
Electrophysiological responses to cholecystokinin (CCK) were studied in Xenopus oocytes injected with mRNA from rabbit pancreas or rat hippocampus. CCK-octapeptide(26–33) (sulfated form) (CCK-8) elicited inward currents in both groups. In oocytes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d605f680e1edf3af454bd787a115a7e
https://doi.org/10.1254/jjp.72.9
https://doi.org/10.1254/jjp.72.9
Autor:
Toshio Fujishita, Kazuo Kawasaki, Masami Eigyo, Takashi Sasatani, Nobuo Chomei, Makoto Adachi, Akira Matsushita, Susumu Takada, Shunji Murata
Publikováno v:
ChemInform. 27
2-Arylimidazo[4,5-c]quinolines and analogous fused imidazopyridines were synthesized and evaluated as benzodiazepine receptor ligands. Affinity to the receptors was greatly affected by the bulkiness of the aryl group at the 2-position, compared to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a29e5c4497f61bf5786f176f60669dc5
https://doi.org/10.1002/chin.199643122
https://doi.org/10.1002/chin.199643122
Autor:
Mitsuru, Yasui, Akira, Kato, Toshiyuki, Kanemasa, Shunji, Murata, Kohei, Nishitomi, Katsumi, Koike, Nobuyuki, Tai, Shunji, Shinohara, Miwa, Tokomura, Masahito, Horiuchi, Kohji, Abe
Publikováno v:
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. 25(3)
We examined the behavioral pharmacological properties of six benzodiazepine (omega) receptor ligands including brotizoram, nitrazepam, quazepam, rilmazafone, zolpidem and zopiclone and the binding of these drugs with omega receptor subtypes. Behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ea92ca5d01cbeddd5f763c4cf999683
https://pubmed.ncbi.nlm.nih.gov/16045197
https://pubmed.ncbi.nlm.nih.gov/16045197
Autor:
Tsuyoshi Kihara, Masato Ikeda, Masami Eigyo, Susumu Takada, Shunji Murata, Kazuo Kawasaki, Katsumi Koike
Publikováno v:
GABA: Receptors, Transporters and Metabolism ISBN: 9783034898584
Pharmacological actions of a novel benzodiazepine partial inverse agonist, S-8510 were examined. S-8510 ameriolated memory impairment induced by cholinergic deficit in rats in addition to augmentation of the LTP in hippocampal slice preparation. Furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d996bebc7280822111eb2d137c964321
https://doi.org/10.1007/978-3-0348-8990-2_28
https://doi.org/10.1007/978-3-0348-8990-2_28
Autor:
Masami Eigyo, Teruo Shiomi, Yuzuru Inoue, Isako Sakaguchi, Chiyomi Ishibashi, Shunji Murata, Kiyotaka Koyabu, Akira Matsushita, Ikuo Adachi, Motohiko Ueda
Publikováno v:
Japanese journal of pharmacology. 65(2)
S-312, S-312-d, but not S-312-l, L-type calcium channel antagonists, showed anticonvulsant effects on the audiogenic tonic convulsions in DBA/2 mice; and their ED50 values were 18.4 (12.8-27.1) mg/kg, p.o. and 15.0 (10.2-23.7) mg/kg, p.o., respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93de976f90a18651cf2253fe0171c86e
https://pubmed.ncbi.nlm.nih.gov/7967231
https://pubmed.ncbi.nlm.nih.gov/7967231
Autor:
Shunji Murata, Kazuo Kawasaki
Publikováno v:
European journal of pharmacology. 239(1-3)
The behavioural significance of the N-methyl-D-aspartate (NMDA) receptor/channel complex was investigated in rats, using different types of antagonists including D-2-amino-phosphonovaleric acid, (+/-)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4573f8e7ca85b0bb736729eade06220
https://pubmed.ncbi.nlm.nih.gov/8223917
https://pubmed.ncbi.nlm.nih.gov/8223917
Autor:
H. Shindo, Susumu Takada, Haruyuki Shintaku, Takashi Sasatani, Nobuo Chomei, Akira Matsushita, Masami Eigyo, Kazuo Kawasaki, Yukio Takahara, Shunji Murata
Publikováno v:
Journal of Medicinal Chemistry. 31:1738-1745
Synthesis and structure-activity relationships of a series of 2-(thien-3-yl)- and 2-(thien-2-yl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-ones are reported. A number of the compounds possessed 1 order of magnitude higher affinity for the receptors th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d107cb842c225c68e72781d45f32bb
https://doi.org/10.1021/jm00117a012
https://doi.org/10.1021/jm00117a012
Autor:
Akira Matsushita, Haruyuki Shintaku, Tsutomu Sugasawa, Kazuyuki Sasakura, Makoto Adachi, Teruo Shiomi, Shunji Murata, Masami Eigyo, Yukio Takahara
Publikováno v:
Journal of Medicinal Chemistry. 28:699-707
A series of 1-azacycloalkyl-1,4-benzodiazepin-2-ones were synthesized from 1-azacycloalkyl-2-benzoylanilines and corresponding imines and then evaluated for their central nervous system activities. Pharmacological data showed that some of these compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372d719b52ddec3afe78889f2fef146b
https://doi.org/10.1021/jm00383a003
https://doi.org/10.1021/jm00383a003
Publikováno v:
ChemInform. 20
2-(5-Alkylthien-3-yl)-(1),2-(4-alkylthien-2-yl)-(2), and 2-(5-alkylthien-2-yl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolines (3) were prepared in four steps starting from ethyl 4-chloroquinoline-3-carboxylate (4) and hydrazinothiophene-carboxylates 5, 8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1f305a7b0511d5aa7599aec8e428b5
https://doi.org/10.1002/chin.198949176
https://doi.org/10.1002/chin.198949176
Publikováno v:
Journal of medicinal chemistry. 32(6)
2-(5-Alkylthien-3-yl)-(1),2-(4-alkylthien-2-yl)-(2), and 2-(5-alkylthien-2-yl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolines (3) were prepared in four steps starting from ethyl 4-chloroquinoline-3-carboxylate (4) and hydrazinothiophene-carboxylates 5, 8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d5aaa09772fb488dd877174ce754b1
https://pubmed.ncbi.nlm.nih.gov/2542554
https://pubmed.ncbi.nlm.nih.gov/2542554