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Akademický článek

Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway

Autor: Chongyang Ma, Xueqian Wang, Tian Xu, Xue Yu, Shuang Zhang, Shuling Liu, Yushan Gao, Shuning Fan, Changxiang Li, Changming Zhai, Fafeng Cheng, Qingguo Wang

Publikováno v: BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-13 (2019)

Abstract Background Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug Administration, has

Externí odkaz: https://doaj.org/article/af41b00f140a4bcb886d9536c35cb60b

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Network pharmacology assessment of Qingkailing injection treatment of cholestatic hepatitis

Autor: Yajun, Lian, Qingguo, Wang, Jie, Mu, Haixia, Liu, Tian, Xu, Shuning, Fan, Feifei, Tang, Tianyi, Feng, Wenxiu, Xu, Na, Jin, Fafeng, Cheng, Xueqian, Wang

Publikováno v: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 41(1)

To investigate the targets and mechanisms of action of Qingkailing injection (，QKL) in the treatment of cholestatic hepatitis.A network pharmacology method was implemented using drug and disease databases to target QKL and cholestasis hepatitis, re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c5fd67125ea53a660f1ac297720482d
https://pubmed.ncbi.nlm.nih.gov/33522210

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Network Pharmacology-Based Approach to Revealing Biological Mechanisms of Qingkailing Injection against IschemicStroke: Focusing on Blood-Brain Barrier

Autor: Kai Lv, Shuang Zhang, Wenxiu Xu, Shuling Liu, Shuning Fan, Chongyang Ma, Xueqian Wang, Fafeng Cheng, Qingguo Wang, Na Jin

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-based Complementary and Alternative Medicine : eCAM

Ischemic stroke is the most common type of cerebrovascular accident worldwide. It causes long-term disability and death. Qingkailing (QKL) injection is a traditional Chinese patent medicine which has been clinically applied in the treatment of ischem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d960206d82cc9de2a402d74170629540
https://doaj.org/article/b955c6d3dfd4496b9b9f736e69933d0d

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Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway

Autor: Xueqian Wang, Changxiang Li, Changming Zhai, Yushan Gao, Shuang Zhang, Shuling Liu, Tian Xu, Shuning Fan, Chongyang Ma, Xue Yu, Fafeng Cheng, Qingguo Wang

Publikováno v: BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-13 (2019)

Background Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug Administration, has been wide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e146c76ac1ef57adc27d21e715e95db
http://europepmc.org/articles/PMC6868863

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Corrigendum to 'Systematic Understanding of the Mechanism of Baicalin against Ischemic Stroke through a Network Pharmacology Approach'

Autor: Tian Xu, Ling Tan, Shuling Liu, Shuang Zhang, Weizhe Du, Xueqian Wang, Beida Ren, Shuning Fan, Nan Deng, Fafeng Cheng, Qingguo Wang, Zhenhan Li, Chongyang Ma, Yajun Lian

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2019 (2019)

Ischemic stroke is accompanied by high mortality and morbidity rates. At present, there is no effective clinical treatment. Alternatively, traditional Chinese medicine has been widely used in China and Japan for the treatment of ischemic stroke. Baic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5eacd6858e66181c754c73f6517089e
https://pubmed.ncbi.nlm.nih.gov/30647760

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Network Pharmacology and Bioinformatics Approach Reveals the Therapeutic Mechanism of Action of Baicalein in Hepatocellular Carcinoma

Autor: Feifei Tang, Wei Wei, Xueqian Wang, Fafeng Cheng, Shuling Liu, Shuang Zhang, Tian Xu, Changxiang Li, Changming Zhai, Shuning Fan, Juan Luo, Chaofang Lei, Xiaoguang Sun, Qingguo Wang, Chongyang Ma

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2019 (2019)
Evidence-based Complementary and Alternative Medicine : eCAM

Liver cancer is the fourth leading cause of cancer death worldwide, and hepatocellular carcinoma (HCC) accounts for the greatest proportion of these deaths. Baicalein, a flavonoid isolated from the root of Scutellariae radix, is considered a potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a710f70d816b54b668684687d5ba040
https://pubmed.ncbi.nlm.nih.gov/30891079

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A 3D Point Cloud Segmentation Method Based on Local Convexity and Dimension Features

Autor: Shuning Fan, Junjie Zhang, Pengfei Fang, Na Huang

Publikováno v: 2018 Chinese Control And Decision Conference (CCDC).

Segmentation of 3D point clouds is an essential part of automatic tasks, such as object classification, recognition, and localization. The segmentation results pose a direct impact on the further processing. In this paper, we present an improved regi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e39c4a8378f5601e2da995ea29718303
https://doi.org/10.1109/ccdc.2018.8408000

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Evidence and perspective for the role of the NLRP3 inflammasome signaling pathway in ischemic stroke and its therapeutic potential (Review)

Autor: Huiling Tian, Tian Xu, Shuang Zhang, Shuning Fan, Yushan Gao, Changxiang Li, Chaofang Lei, Changming Zhai, Yuxi Chen, Xue Yu, Qingguo Wang, Chongyang Ma, Fafeng Cheng, Xueqian Wang, Shuling Liu

Publikováno v: International journal of molecular medicine. 42(6)

Ischemic stroke is one of the main causes of death and disablement globally. The NLR family pyrin domain containing 3 (NLRP3) inflammasome is established as a sensor of detecting cellular damage and modulating inflammatory responses to injury during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cf9348fdcca85c3a24badf3196e5db
https://pubmed.ncbi.nlm.nih.gov/30280193

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Systematic Understanding of the Mechanism of Baicalin against Ischemic Stroke through a Network Pharmacology Approach

Autor: Shuling Liu, Nang Deng, Ling Tan, Qinguo Wang, Tian Xu, Beida Ren, Yajun Lian, Shuning Fan, Chongyang Ma, Weizhe Du, Fafeng Cheng, Xueqian Wang, Shuang Zhang, Zhenhan Li

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2018 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9713a307ae61470e4e5d0b55d5f50e56

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