Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shunichiro Matsumoto"'
Autor:
Masashi Hiramoto, Masatoshi Yuri, Mitsuyuki Matsumoto, Keitaro Mori, Masanori Naito, Shunichiro Matsumoto, Hiroyuki Yokota, Shuji Morita, Toshio Teramura
Publikováno v:
Journal of Proteome Research. 10:2658-2663
SREB2 (GPR85) is an orphan G-protein coupled receptor (GPCR) whose function is unknown. We previously prepared a SREB2-overexpressing transgenic mouse for functional analysis but were unable to confirm SREB2 protein expression level by immunochemical
Autor:
Chihiro Yamazaki, Masayasu Yoshino, Masanori Naitou, Takeshi Kurama, Akira Suwa, Shunichiro Matsumoto, Rie Fujikawa, Ichiro Aramori, Teruhiko Shimokawa
Publikováno v:
FEBS Journal. 277:677-686
The aim of this study is to discover and characterize novel energy homeostasis-related molecules. We screened stock mouse embryonic stem cells established using the exchangeable gene trap method, and examined the effects of deficiency of the target g
Autor:
Akira Miyake, Shinji Takahashi, Masao Katou, Shunichiro Matsumoto, Kohei Inamura, Yukihiro Nakamura, Shinobu Mochizuki
Publikováno v:
The Journal of Neuroscience. 29:14637-14645
The K+channel, one of the determinants for neuronal excitability, is genetically heterogeneous, and various K+channel genes are expressed in the CNS. The therapeutic potential of K+channel blockers for cognitive enhancement has been discussed, but th
Autor:
Ayako Matsuo, Mamoru Nagano, Masazumi Kamohara, Masato Kobori, Masao Katoh, Shunichiro Matsumoto, Kiyoshi Furuichi, Hideki Hiyama, Yasufumi Shigeyoshi, Mitsuyuki Matsumoto, Hitoshi Matsushime, Chihiro Yamazaki, Takatoshi Soga, Koh-hei Masumoto, Masanori Naito, Jun Takasaki, Hiroyuki Ishii
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4140-4145
Prokineticins, multifunctional secreted proteins, activate two endogenous G protein-coupled receptors PKR1 and PKR2. From in situ analysis of the mouse brain, we discovered that PKR2 is predominantly expressed in the olfactory bulb (OB). To examine t
Autor:
Hideki Hiyama, Masato Kobori, Ayako Matsuo, Masao Katou, Masanobu Kohda, Masazumi Kamohara, Mitsuyuki Matsumoto, Takatoshi Soga, Shunichiro Matsumoto, Jun Takasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 330:1146-1152
Proadrenomedullin N-terminal 20 peptide (PAMP[1-20]/PAMP-20) and its truncated analog, PAMP[9-20]/PAMP-12, are endogenous peptides that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffi
Autor:
Takahide Ohishi, Hitoshi Matsushime, Tetsu Saito, Takatoshi Soga, Masazumi Kamohara, Kiyoshi Furuichi, Masato Kobori, Mitsuyuki Matsumoto, Shunichiro Matsumoto, Hideki Hiyama, Jun Takasaki, Tetsuo Matsui, Kazuhiro Momose, Yoshitaka Ueda, Shigeru Yoshida
Publikováno v:
Biochemical and Biophysical Research Communications. 326:744-751
A lysophospholipid series, such as lysophosphatidic acid, lysophosphatidylserine, and lysophosphatidylcholine (LPC), is a bioactive lipid mediator with diverse physiological and pathological functions. LPC has been reported to induce insulin secretio
Autor:
Tetsu Saito, Jun Takasaki, Kiyoshi Furuichi, Masazumi Kamohara, Hitoshi Matsushime, Takatoshi Soga, Shunichiro Matsumoto, Mitsuyuki Matsumoto
Publikováno v:
Biochemical and Biophysical Research Communications. 287:1088-1092
Cysteinyl leukotrienes (LTC(4), LTD(4), and LTE(4)) are a class of biologically active lipids that exert potent effects on the heart. To assess their roles, we investigated the distribution of their receptors, CysLT(1) and CysLT(2), in the cardiovasc
Autor:
Shunichiro Matsumoto, Tamaki Oda
Publikováno v:
Folia Pharmacologica Japonica. 118:36-42
Recently, we and other groups have identified cDNA encoding the novel histamine H4 receptor. All of the groups have initially found a clue for the H4 receptor-nucleotides sequence in the human draft genomic DNA database. The primary structure of H4 r
Autor:
Kiyoshi Furuichi, Tetsu Saito, Masato Kobayashi, Toru Sugimoto, Jun Takasaki, Takahide Ohishi, Mina Tadokoro, Masazumi Kamohara, Mitsuyuki Matsumoto, Shunichiro Matsumoto
Publikováno v:
Biochemical and Biophysical Research Communications. 272:576-582
We report here a novel family of G-protein coupled receptor (GPCR) which is extraordinarily conserved among vertebrate species. This family, designated SREB (Super Conserved Receptor Expressed in Brain), consists of at least three members, termed SRE
Autor:
Kunio Yasunaga, Tetsu Saito, Noboru Yamaji, Shunichiro Matsumoto, Kobayashi Seiji, Shigeki Saito, Masao Katoh, Yasuhiko Masuho
Publikováno v:
Journal of Biological Chemistry. 274:30756-30763
The extra domain-A (EDA), present in fibronectin (FN) molecules arising from alternatively spliced transcripts, appears only during specific biological and pathogenic processes. However, its function is poorly understood. To define the physiologic ro