Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shunichi Asai"'
Autor:
Kengo Tanigawa, Yuya Tomioka, Shunsuke Misono, Shunichi Asai, Naoko Kikkawa, Yoko Hagihara, Takayuki Suetsugu, Hiromasa Inoue, Keiko Mizuno, Naohiko Seki
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1737-1755 (2023)
Lung cancer is the most common cause of cancer‐related death worldwide, accounting for 1.8 million deaths annually. Analysis of The Cancer Genome Atlas data showed that all members of the minichromosome maintenance (MCM) family (hexamers involved i
Externí odkaz:
https://doaj.org/article/05f078ab823e43088c262c888b2bfd21
Autor:
Kengo Tanigawa, Shunsuke Misono, Keiko Mizuno, Shunichi Asai, Takayuki Suetsugu, Akifumi Uchida, Minami Kawano, Hiromasa Inoue, Naohiko Seki
Publikováno v:
Molecular Oncology, Vol 17, Iss 2, Pp 328-343 (2023)
Small‐cell lung cancer (SCLC) is associated with a high mortality rate and limited treatment efficacy. We created a microRNA (miRNA) expression signature by RNA sequencing using specimens from patients with SCLC who had failed treatment. Forty‐ni
Externí odkaz:
https://doaj.org/article/389557d4be3148dcbab70b1db4f13262
Autor:
Yuya Tomioka, Takayuki Suetsugu, Naohiko Seki, Kengo Tanigawa, Yoko Hagihara, Masahiro Shinmura, Shunichi Asai, Naoko Kikkawa, Hiromasa Inoue, Keiko Mizuno
Publikováno v:
Cells, Vol 12, Iss 14, p 1885 (2023)
The involvement of passenger strands of miRNAs in the molecular pathogenesis of human cancers is a recent concept in miRNA research, and it will broaden our understanding of the molecular mechanisms of miRNA-mediated cancer. The analysis of our miRNA
Externí odkaz:
https://doaj.org/article/1781bf32359c4c1491d712d29086c537
Autor:
Kosei Mori, Kazuki Yamasaki, Yuki Morimoto, Takashi Kinoshita, Shunichi Asai, Tomoyuki Arai, Tomohisa Iinuma, Syuji Yonekura, Toyoyuki Hanazawa
Publikováno v:
Life, Vol 12, Iss 11, p 1685 (2022)
Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignant salivary gland tumor, and its prognosis is determined by the histological progression beyond the adenoma capsule. However, a preoperative evaluation of the histological progression remains c
Externí odkaz:
https://doaj.org/article/f9cf0455dd1e45eca87c3e49ddd915a3
Autor:
Shunichi Asai, Ayaka Koma, Nijiro Nohata, Takashi Kinoshita, Naoko Kikkawa, Mayuko Kato, Chikashi Minemura, Katsuhiro Uzawa, Toyoyuki Hanazawa, Naohiko Seki
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 663 (2022)
Based on our original RNA sequence-based microRNA (miRNA) signatures of head and neck squamous cell carcinoma (HNSCC), it was revealed that the expression levels of miR-1-3p, miR-206, miR-133a-3p, and miR-133b were significantly suppressed in cancer
Externí odkaz:
https://doaj.org/article/0070b7244f304fff90df7dff5f400069
Autor:
Keiko Mizuno, Kengo Tanigawa, Shunsuke Misono, Takayuki Suetsugu, Hiroki Sanada, Akifumi Uchida, Minami Kawano, Kentaro Machida, Shunichi Asai, Shogo Moriya, Hiromasa Inoue, Naohiko Seki
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1883 (2021)
Several recent studies have shown that both strands of certain miRNAs derived from miRNA duplexes are involved in cancer pathogenesis. Our own recent studies revealed that both strands of the miR-150 duplex act as tumor-suppressive miRNAs in lung ade
Externí odkaz:
https://doaj.org/article/da15be8112484a20a188a0fdd02b5a81
Autor:
Reona Okada, Yusuke Goto, Yasutaka Yamada, Mayuko Kato, Shunichi Asai, Shogo Moriya, Tomohiko Ichikawa, Naohiko Seki
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 599 (2020)
We previously found that both the guide and passenger strands of the miR-139 duplex (miR-139-5p and miR-139-3p, respectively) were downregulated in cancer tissues. Analysis of TCGA datasets revealed that low expression of miR-139-5p (p < 0.0001) and
Externí odkaz:
https://doaj.org/article/3c490d4bbf9249108b2b4eb362ae00a7
Autor:
Keiko Mizuno, Kengo Tanigawa, Nijiro Nohata, Shunsuke Misono, Reona Okada, Shunichi Asai, Shogo Moriya, Takayuki Suetsugu, Hiromasa Inoue, Naohiko Seki
Publikováno v:
Cells, Vol 9, Iss 9, p 2083 (2020)
Lung adenocarcinoma (LUAD) is the most aggressive cancer and the prognosis of these patients is unfavorable. We revealed that the expression levels of both strands of miR-99a (miR-99a-5p and miR-99a-3p) were significantly suppressed in several cancer
Externí odkaz:
https://doaj.org/article/53a3e75b6ffc407f954504e22991b665
Autor:
Shunichi Asai, Yusuke Goto, Kengo Tanigawa, Yuya Tomioka, Mayuko Kato, Keiko Mizuno, Shinichi Sakamoto, Naohiko Seki
Publikováno v:
FEBS Letters. 597:1164-1175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08aece849dc8a59385ee54f5f5ea2943
https://doi.org/10.1002/1873-3468.14598
https://doi.org/10.1002/1873-3468.14598
Autor:
Yusuke Goto, Shunichi Asai, Shinichi Sakamoto, Tomokazu Sazuka, Yusuke Imamura, Naohiko Seki, Tomohiko Ichikawa
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3836ab31ab9e1590365b22de396b656c
https://doi.org/10.1097/ju.0000000000003245.03
https://doi.org/10.1097/ju.0000000000003245.03