Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Shunheng Zhou"'
Autor:
Haizhou Liu, Mengqin Yuan, Ramkrishna Mitra, Xu Zhou, Min Long, Wanyue Lei, Shunheng Zhou, Yu-e Huang, Fei Hou, Christine M. Eischen, Wei Jiang
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Pathway enrichment analysis (PEA) is a common method for exploring functions of hundreds of genes and identifying disease-risk pathways. Moreover, different pathways exert their functions through crosstalk. However, existing PEA m
Externí odkaz:
https://doaj.org/article/854ec60e76444feaa973fc855e144448
Publikováno v:
Advanced Science, Vol 10, Iss 14, Pp n/a-n/a (2023)
Abstract Adenosine‐to‐inosine RNA editing critically affects the response of cancer therapies. However, comprehensive identification of drug resistance‐related RNA editing events and systematic understanding of how RNA editing mediates anticanc
Externí odkaz:
https://doaj.org/article/bd2943edeb3647bba10a1dcdd259540c
Autor:
Fei Hou, Xu Zhou, Shunheng Zhou, Haizhou Liu, Yu-e Huang, Mengqin Yuan, Jicun Zhu, Xinyu Cao, Wei Jiang
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104493- (2022)
Long-term isolation is one of the risk factors that astronauts will encounter in spaceflight. At present, few researches have explored DNA methylation dynamics during long-term isolation. In this study, using time series DNA methylation data from “
Externí odkaz:
https://doaj.org/article/92a323e1e3bb49c28e72ea7a765a5dd0
Autor:
Shunheng Zhou, Yu-e Huang, Haizhou Liu, Xu Zhou, Mengqin Yuan, Fei Hou, Lihong Wang, Wei Jiang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 682-690 (2021)
Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high intratumoral heterogeneity. Recent studies revealed that TNBC patients might comprise cells with distinct molecular subtypes. In addition, gene regulatory networks (GRNs) co
Externí odkaz:
https://doaj.org/article/973d41588a984fd3b7dd0ef6eaff3f44
Autor:
Xiao Tong, Zhengling Yu, Jiani Xing, Haizhou Liu, Shunheng Zhou, Yu’e Huang, Jing Lin, Wei Jiang, Lihong Wang
Publikováno v:
Cancers, Vol 15, Iss 6, p 1880 (2023)
Background: Long non-coding RNAs (lncRNAs) are a class of RNA molecules that are longer than 200 nucleotides and were initially believed to lack encoding capability. However, recent research has found open reading frames (ORFs) within lncRNAs, sugges
Externí odkaz:
https://doaj.org/article/4c9cccb00bf246dc91bd13ead5b3f14b
Autor:
Shuyuan Wang, Shunheng Zhou, Haizhou Liu, Qianqian Meng, Xueyan Ma, Hui Liu, Lihong Wang, Wei Jiang
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-5 (2020)
Abstract Background Inflammation has been considered to be central to the onset, progression, and outcome of infectious diseases, especially as one of the hallmarks of cancer. Non-coding RNAs (ncRNAs), such as miRNAs and lncRNAs, have emerged as vita
Externí odkaz:
https://doaj.org/article/dc7c447dadb64c7bb6cf1bbcffb83f89
Autor:
Sina Chen, Shunheng Zhou, Yu-e Huang, Mengqin Yuan, Wanyue Lei, Jiahao Chen, Kongxuan Lin, Wei Jiang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15020 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is characterized by intra-tumoral heterogeneity, and patients are always diagnosed after metastasis. Thus, finding out how to effectively estimate metastatic risk underlying PDAC is necessary. In this study, we
Externí odkaz:
https://doaj.org/article/e88dfbf8b1f44f478f224ec32613c0a5
Publikováno v:
Cancer Medicine, Vol 8, Iss 9, Pp 4389-4403 (2019)
Abstract Emerging evidence has suggested that long noncoding RNAs (lncRNA) involved in the development and progression of cancer. Triple negative breast cancer (TNBC) was an aggressive type of breast cancer with high rates of cancer recurrence and me
Externí odkaz:
https://doaj.org/article/6181545da76240d29891feef25698718
Autor:
Haizhou Liu, Shuyuan Wang, Shunheng Zhou, Qianqian Meng, Xueyan Ma, Xiaofeng Song, Lihong Wang, Wei Jiang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 442-451 (2019)
Drug resistance is a common cause of treatment failure in cancer therapy, and molecular mechanisms need further exploration. Competing endogenous RNAs (ceRNAs) can influence drug response by participating in various biological processes, including re
Externí odkaz:
https://doaj.org/article/e7be783b53924be5b7e85c515f5e5909
DRdriver: identifying drug resistance driver genes using individual-specific gene regulatory network
Autor:
Yu-e Huang, Shunheng Zhou, Haizhou Liu, Xu Zhou, Mengqin Yuan, Fei Hou, Sina Chen, Jiahao Chen, Lihong Wang, Wei Jiang
Publikováno v:
Briefings in Bioinformatics. 24
Drug resistance is one of principal limiting factors for cancer treatment. Several mechanisms, especially mutation, have been validated to implicate in drug resistance. In addition, drug resistance is heterogeneous, which makes an urgent need to expl