Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shungo Kumada"'
Autor:
Atsushi Kosugi, Kok Hoong Leong, Eri Urata, Yoshihiro Hayashi, Shungo Kumada, Kotaro Okada, Yoshinori Onuki
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 886 (2020)
This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets. After preparing the model tablets with different values of hardness, they were stored at 25
Externí odkaz:
https://doaj.org/article/43c839b681b249fc81fbe6aab70708ef
Autor:
Yoshihiro Hayashi, Kaede Shirotori, Atsushi Kosugi, Shungo Kumada, Kok Hoong Leong, Kotaro Okada, Yoshinori Onuki
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 601 (2020)
We previously reported a novel method for the precise prediction of tablet properties (e.g., tensile strength (TS)) using a small number of experimental data. The key technique of this method is to compensate for the lack of experimental data by usin
Externí odkaz:
https://doaj.org/article/6baa12300c644da5bab24c1b6d66a181
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:406-415
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1041-1051
Autor:
Takahiro Tsuji, Ryosuke Kobayashi, Yoshihiro Hayashi, Shungo Kumada, Mineyuki Mizuguchi, Kotaro Okada, Yoshinori Onuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:558-565
Autor:
Yuya, Chiba, Kotaro, Okada, Yoshihiro, Hayashi, Kok Hoong, Leong, Shungo, Kumada, Yoshinori, Onuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:162-168
NMR relaxometry measurement by time domain NMR (TD-NMR) is a promising technique for characterizing the properties of active pharmaceutical ingredients (APIs). This study is dedicated to identifying the salt and free base of APIs by NMR relaxometry m
Autor:
Hinako Tsuji, Shungo Kumada, Yoshihiro Hayashi, Kok Hoong Leong, Yoshinori Onuki, Atsushi Kosugi, Kotaro Okada
Publikováno v:
Journal of Pharmaceutical Sciences. 109:2585-2593
The purpose of this study was to accumulate enhanced technical knowledge about the powder properties of direct compaction grades of mannitol that could lead to new tablet formulations. Fifteen different commercial direct compaction grades of mannitol
Publikováno v:
Journal of Pharmaceutical Sciences. 109:2577-2584
We sought to demonstrate the usefulness of the T2 relaxation behaviors measured by time domain NMR (TD-NMR) for the quantitative evaluation of the crystallinity of an active pharmaceutical ingredient (API). This study used indomethacin as a model API
Publikováno v:
International journal of pharmaceutics. 609
This study investigates the usefulness of machine learning for modeling complex relationships in a material library. We tested 81 types of active pharmaceutical ingredients (APIs) and their tablets to construct the library, which included the followi
Autor:
Shungo Kumada, Atsushi Kosugi, Daijiro Hirai, Kotaro Okada, Yoshihiro Hayashi, Yoshinori Onuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:580-586
The aim of this study was to demonstrate the usefulness of T2 measurements conducted with a time-domain NMR (TD-NMR) for the characterization of active pharmaceutical ingredients (APIs) containing solid dosage forms. A solid dispersion (SD) and a phy