Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Shun-ichiro Iemura"'
Autor:
Yosuke Yoneyama, Tomomi Inamitsu, Kazuhiro Chida, Shun-Ichiro Iemura, Tohru Natsume, Tatsuya Maeda, Fumihiko Hakuno, Shin-Ichiro Takahashi
Publikováno v:
iScience, Vol 5, Iss , Pp 1-18 (2018)
Summary: The insulin receptor substrate IRS-1 is a key substrate of insulin and insulin-like growth factor (IGF) receptor tyrosine kinases that mediates their metabolic and growth-promoting actions. Proteasomal degradation of IRS-1 is induced followi
Externí odkaz:
https://doaj.org/article/2757bc1447bc46bca0097f56b63c651f
Autor:
Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Yes-associated protein (YAP) is a growth-promoting transcription co-activator that regulates the malignancy of various cancers, however its regulation is not fully understood. Here the authors show that phosphatdylserine at recycling endosomes regula
Externí odkaz:
https://doaj.org/article/b6f3cf39d78c4ceca7b038e194e9bed2
Autor:
Yoshinori Tsukumo, Satomi Tsukahara, Aki Furuno, Shun-ichiro Iemura, Toru Natsume, Akihiro Tomida
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112761 (2014)
Under ER stress, PKR-like ER-resident kinase (PERK) phosphorylates translation initiation factor eIF2α, resulting in repression of global protein synthesis and concomitant upregulation of the translation of specific mRNAs such as activating transcri
Externí odkaz:
https://doaj.org/article/39d30275341b41f8917e887f66f2c707
Autor:
Toshiyasu Goto, Atsushi Sato, Masahiro Shimizu, Shungo Adachi, Kiyotoshi Satoh, Shun-ichiro Iemura, Tohru Natsume, Hiroshi Shibuya
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60865 (2013)
Dishevelled (DVL) is a central factor in the Wnt signaling pathway, which is highly conserved among various organisms. DVL plays important roles in transcriptional activation in the nucleus, but the molecular mechanisms underlying their nuclear local
Externí odkaz:
https://doaj.org/article/0f8a6e6b7bd147cf9cfd05dae30f8027
Autor:
Katsuhiro Murakami, Yuzuru Ichinohe, Masaaki Koike, Norio Sasaoka, Shun-ichiro Iemura, Tohru Natsume, Akira Kakizuka
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56012 (2013)
Catalase is a key antioxidant enzyme that catalyzes the decomposition of hydrogen peroxide (H2O2) to water and oxygen, and it appears to shuttle between the cytoplasm and peroxisome via unknown mechanisms. Valosin-containing protein (VCP) belongs to
Externí odkaz:
https://doaj.org/article/64d9a17874564dbcbd0672700be7fd68
Autor:
Sayaka Akieda-Asai, Nobuhiro Zaima, Koji Ikegami, Tomoaki Kahyo, Ikuko Yao, Takahiro Hatanaka, Shun-Ichiro Iemura, Rika Sugiyama, Takeaki Yokozeki, Yoshinobu Eishi, Morio Koike, Kyoji Ikeda, Takuya Chiba, Haruyoshi Yamaza, Isao Shimokawa, Si-Young Song, Akira Matsuno, Akiko Mizutani, Motoji Sawabe, Moses V Chao, Masashi Tanaka, Yasunori Kanaho, Tohru Natsume, Haruhiko Sugimura, Yukari Date, Michael W McBurney, Leonard Guarente, Mitsutoshi Setou
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11755 (2010)
BACKGROUND: SIRT1, a NAD-dependent deacetylase, has diverse roles in a variety of organs such as regulation of endocrine function and metabolism. However, it remains to be addressed how it regulates hormone release there. METHODOLOGY/PRINCIPAL FINDIN
Externí odkaz:
https://doaj.org/article/058e2cab7c54476c87f498a588a61b8b
Autor:
Tamio Mizukami, Ryuzo Sasaki, Shinji Ohta, Yukio Mukai, Shu-ichi Wada, Tohru Natsume, Shun-ichiro Iemura, Naoki Goshima, Kazuo Shin-ya, Motoki Takagi, Masayuki Sekigawa, Koichi Koseki, Takanori Noda, Tatsuki Kunoh
Supplementary Table 1 from A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d64661a01ffce54845385cbda0a5c5
https://doi.org/10.1158/1535-7163.22500748.v1
https://doi.org/10.1158/1535-7163.22500748.v1
Autor:
Tamio Mizukami, Ryuzo Sasaki, Shinji Ohta, Yukio Mukai, Shu-ichi Wada, Tohru Natsume, Shun-ichiro Iemura, Naoki Goshima, Kazuo Shin-ya, Motoki Takagi, Masayuki Sekigawa, Koichi Koseki, Takanori Noda, Tatsuki Kunoh
Supplementary Figure 1 from A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69af1ffd159eb673299d8ac66f39364b
https://doi.org/10.1158/1535-7163.22500778
https://doi.org/10.1158/1535-7163.22500778
Autor:
Tamio Mizukami, Ryuzo Sasaki, Shinji Ohta, Yukio Mukai, Shu-ichi Wada, Tohru Natsume, Shun-ichiro Iemura, Naoki Goshima, Kazuo Shin-ya, Motoki Takagi, Masayuki Sekigawa, Koichi Koseki, Takanori Noda, Tatsuki Kunoh
Supplementary Figure Legends from A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ebd79189defa3f46e1a86d23fde721
https://doi.org/10.1158/1535-7163.22500751.v1
https://doi.org/10.1158/1535-7163.22500751.v1
Autor:
Tamio Mizukami, Ryuzo Sasaki, Shinji Ohta, Yukio Mukai, Shu-ichi Wada, Tohru Natsume, Shun-ichiro Iemura, Naoki Goshima, Kazuo Shin-ya, Motoki Takagi, Masayuki Sekigawa, Koichi Koseki, Takanori Noda, Tatsuki Kunoh
Supplementary Table 2 from A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f8276a03180a464e519b4a3667acbf
https://doi.org/10.1158/1535-7163.22500745.v1
https://doi.org/10.1158/1535-7163.22500745.v1