Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shun-Ichi Wakabayashi"'
Autor:
Taiki Okumura, Takefumi Kimura, Yuki Ichikawa, Takanobu Iwadare, Shun-ichi Wakabayashi, Hiroyuki Kobayashi, Yuki Yamashita, Takuro Uchida, Sai P. Pydi, Naoki Tanaka, Takeji Umemura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Thrombospondin 2 (TSP2) plays a vital role in collagen/fibrin formation, bone growth, vascular density regulation, hemostasis, and cell adhesion. Close associations of serum TSP2 with histological severity in non-alcoholic fatty liver diseas
Externí odkaz:
https://doaj.org/article/efbf9c3f37394982aa014cb4798abd89
Autor:
Takanobu Iwadare, Takefumi Kimura, Taiki Okumura, Shun-ichi Wakabayashi, Taro Nakajima, Shohei Kondo, Hiroyuki Kobayashi, Yuki Yamashita, Ayumi Sugiura, Naoyuki Fujimori, Tomoo Yamazaki, Hideo Kunimoto, Satoshi Shimamoto, Koji Igarashi, Satoru Joshita, Naoki Tanaka, Takeji Umemura
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Background Circulating autotaxin (ATX) levels have been reported to correlate with liver inflammation activity and liver fibrosis severity in patients with non-alcoholic fatty liver disease (NAFLD). The objective of this study is to investig
Externí odkaz:
https://doaj.org/article/7bd204aa7e9f4f2cbac9920231994507
Autor:
Takanobu Iwadare, Takefumi Kimura, Hideo Kunimoto, Taiki Okumura, Shun-Ichi Wakabayashi, Hiroyuki Kobayashi, Yuki Yamashita, Ayumi Sugiura, Naoki Tanaka, Takeji Umemura
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
AimShort-term use of pemafibrate (PEM), a selective modulator of peroxisome proliferator-activated receptor alpha, has been reported to improve abnormal liver function in patients with nonalcoholic fatty liver disease with hypertriglyceridemia (HTG-N
Externí odkaz:
https://doaj.org/article/a1f84d912d96457280986941cd66bf83
Autor:
Shun‐Ichi Wakabayashi, Satoru Joshita, Kazuhiro Kimura, Hirohiko Motoki, Taiki Okumura, Hiroyuki Kobayashi, Yuki Yamashita, Ayumi Sugiura, Tomoo Yamazaki, Takefumi Kimura, Koichiro Kuwahara, Takeji Umemura
Publikováno v:
JGH Open, Vol 7, Iss 8, Pp 527-536 (2023)
Abstract Background and Aim As the exact prevalence of portopulmonary hypertension (PoPH) and the etiology of chronic liver disease (CLD) remain unknown, the present study aimed to clarify these points in Japanese patients with CLD using symptom‐ba
Externí odkaz:
https://doaj.org/article/9e32efad0ee4408f9ea877da2088beab
Pyogenic liver abscess associated with Klebsiella oxytoca: Mimicking invasive liver abscess syndrome
Autor:
Takanobu Iwadare, Takefumi Kimura, Ayumi Sugiura, Risa Takei, Masato Kamakura, Shun-ichi Wakabayashi, Taiki Okumura, Daichi Hara, Akira Nakamura, Takeji Umemura
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21537- (2023)
A pyogenic liver abscess (PLA) is a space-occupying lesion in the liver that is associated with significant morbidity and mortality. We herein present the case of a Japanese 76-year-old man who visited our hospital with fever and back pain lasting 3
Externí odkaz:
https://doaj.org/article/b85408407cd94cf991ddb56af7f930b3
Autor:
Takanobu Iwadare, Takefumi Kimura, Naoki Tanaka, Tomoo Yamazaki, Shun-ichi Wakabayashi, Taiki Okumura, Hiroyuki Kobayashi, Yuki Yamashita, Sai P. Pydi, Tomoyuki Nakajima, Mai Iwaya, Ayumi Sugiura, Satoru Joshita, Takeshi Uehara, Takeji Umemura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Among several secreted glycoproteins belonging to the thrombospondin family, thrombospondin 2 (TSP2) is involved in various functions, including collagen/fibrin formation. Liver/serum TSP2 levels have been correlated to liver fibrosis stage
Externí odkaz:
https://doaj.org/article/cbb74aa4f06742c78b5d032babd3d074
Autor:
Satoru Joshita, Masao Ota, Hiroyuki Kobayashi, Shun-ichi Wakabayashi, Yuki Yamashita, Ayumi Sugiura, Tomoo Yamazaki, Eiji Tanaka, Takeji Umemura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Natural killer cells are modulated through the binding of killer cell immunoglobulin-like receptors (KIRs) with human leukocyte antigen (HLA) class I ligands. This study investigated the association of KIR/HLA pairs with progression to liver
Externí odkaz:
https://doaj.org/article/bee59a4b231c4c6bad472af7ff358ea0
Autor:
Takanobu Iwadare, Takefumi Kimura, Hideo Kunimoto, Naoki Tanaka, Shun-ichi Wakabayashi, Tomoo Yamazaki, Taiki Okumura, Hiroyuki Kobayashi, Yuki Yamashita, Ayumi Sugiura, Satoru Joshita, Takeji Umemura
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2806 (2022)
Aim: Pemafibrate (PEM) is a novel selective peroxisome proliferator-activated receptor alpha modulator that is effective for hypertriglyceridemia accompanying non-alcoholic fatty liver disease (HTG-NAFLD). This study aimed to identify the predictors
Externí odkaz:
https://doaj.org/article/3d186cd5093e4b09bd64029b1ab4327c
Autor:
Shun-Ichi Wakabayashi, Satoru Joshita, Kazuhiro Kimura, Hirohiko Motoki, Hiroyuki Kobayashi, Yuki Yamashita, Ayumi Sugiura, Tomoo Yamazaki, Koichiro Kuwahara, Takeji Umemura
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249435 (2021)
BackgroundPortopulmonary hypertension (PoPH) is a subtype of the pulmonary arterial hypertension (PAH) associated with portal hypertension. There is a dissociation between the proportion of PoPH in PAH and that of PoPH in patients with liver cirrhosi
Externí odkaz:
https://doaj.org/article/6fc9ff7c614b415aa99fd1f35e013e0b
Autor:
Hiroyuki Kobayashi, Satoru Joshita, Yuki Akahane, Katsuhiko Matsuzaki, Hiromi Yamada, Daiki Aomura, Nao Joshita, Hajime Midorikawa, Kazuhiro Suyama, Masao Ota, Shun-Ichi Wakabayashi, Yuki Yamashita, Ayumi Sugiura, Tomoo Yamazaki, Hiromichi Misawa, Takeji Umemura
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256711 (2021)
BackgroundThe World Health Organization has set a goal of hepatitis C virus (HCV) elimination by the year 2030. However, no regions in Japan have succeeded in eradicating HCV. Micro-elimination is an approach to attain hepatitis C eradication in whic
Externí odkaz:
https://doaj.org/article/6dabe51c0eab4594940525b85f8f8933