Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shun Doi"'
Autor:
Masao Nakajima, Shoichi Hazama, Yukio Tokumitsu, Yoshitaro Shindo, Hiroto Matsui, Satoshi Matsukuma, Yuki Nakagami, Koji Tamada, Keiko Udaka, Michiie Sakamoto, Akira Saito, Yasunari Kouki, Toshinari Uematsu, Ming Xu, Michihisa Iida, Ryouichi Tsunedomi, Nobuaki Suzuki, Shigeru Takeda, Tatsuya Ioka, Shun Doi, Hiroaki Nagano
Publikováno v:
Hepatology Research.
Autor:
Shin Yoshida, Akira Saito, Nobuaki Suzuki, Yuki Nakagami, Hiroto Matsui, Koji Tamada, Michihisa Iida, Hiroaki Nagano, Masao Nakajima, Shigefumi Yoshino, Shigeru Takeda, Toshinari Uematsu, Hideki Arima, Yasunobu Kouki, Tomio Ueno, Satoshi Matsukuma, Shinobu Tomochika, Shigeru Yamamoto, Shun Doi, Keiko Udaka, Yoshitaro Shindo, Yukio Tokumitsu, Shoichi Hazama, Shinsuke Kanekiyo
Publikováno v:
Cancer Immunology, Immunotherapy
Background This phase I study aimed to evaluate the safety, peptide-specific immune responses, and anti-tumor effects of a novel vaccination therapy comprising multi-HLA-binding heat shock protein (HSP) 70/glypican-3 (GPC3) peptides and a novel adjuv
Autor:
Tomio Ueno, Shigeru Takeda, Yasuharu Nishimura, Shoichi Hazama, Shinobu Tomochika, Atsushi Irie, Tomoya Miyakawa, Yukio Tokumitsu, Masao Nakajima, Hiroaki Nagano, Shigeru Yamamoto, Shin Yoshida, Shun Doi, Nobuaki Suzuki, Shinsuke Kanekiyo, Koji Tamada, Hiroto Matsui, Yoshitaro Shindo, Keiko Udaka, Michihisa Iida, Shigefumi Yoshino
Publikováno v:
Journal of Immunotherapy (Hagerstown, Md. : 1997)
Supplemental Digital Content is available in the text.
We previously found that heat-shock protein 70 (HSP70) is expressed on hepatocellular carcinoma cells and developed an HSP70 mRNA-transfected dendritic cell therapy for treating unresectable
We previously found that heat-shock protein 70 (HSP70) is expressed on hepatocellular carcinoma cells and developed an HSP70 mRNA-transfected dendritic cell therapy for treating unresectable
Autor:
Shoichi Hazama, Tomoya Miyakawa, Koji Tamada, Takahiro Iguchi, Yukimi Sakoda, Keishi Adachi, Hiroto Matsui, Shun Doi, Yosuke Kano, Hiroaki Nagano, Yoshiya Ueyama
Publikováno v:
Cancer Science
Therapeutic cancer vaccines are designed to treat cancer by boosting the endogenous immune system to fight against the cancer. In the development of clinically effective cancer vaccines, one of the most practical objectives is to identify adjuvants t
Autor:
Hiroto Matsui, Shiro Akinaga, Satoshi Matsukuma, Yoshitaro Shindo, Akira Saito, Nobuaki Suzuki, Shigeru Takeda, Michihisa Iida, Masao Nakajima, Yuki Nakagami, Shun Doi, Yukio Tokumitsu, Shin Yoshida, Keiko Udaka, Koji Tamada, Ryouichi Tsunedomi, Hiroaki Nagano, Michiie Sakamoto, Shinobu Tomochika, Shoichi Hazama
Publikováno v:
Cancer Research. 80:CT251-CT251
Background: Even with curative resection, the recurrence rate of HCC remains high, and effective adjuvant therapies are not currently available. Our previous Phase I study with novel therapeutic peptides and immune adjuvants demonstrated safety, anti
Autor:
Nobuaki Suzuki, Toshinari Uematsu, Yuki Nakagami, Koji Tamada, Shigefumi Yoshino, Michihisa Iida, Shinsuke Kanekiyo, Yoshitaro Shindo, Shinobu Tomochika, Shoichi Hazama, Shun Doi, Yukio Tokumitsu, Keiko Udaka, Hiroaki Nagano, Yasunari Koki, Tomio Ueno, Hiroto Matsui, Shiro Akinaga, Shigeru Takeda, Shin Yoshida
Publikováno v:
Journal of Clinical Oncology. 37:e14306-e14306
e14306 Background: Even with curative resection, the recurrence rate of HCC is still high, and no effective adjuvant therapy is currently available. Our previous Phase I study with novel therapeutic peptides and immune adjuvants demonstrated the safe
Publikováno v:
Choonpa Igaku. 39:305-315
Autor:
Yukio Tokumitsu, Koji Tamada, Tomoya Miyakawa, Kazuhiko Sakamoto, Tomomitsu Satoh, Nobuaki Suzuki, Shigeru Yamamoto, Hideki Arima, Shinsuke Kanekiyo, Tomio Ueno, Toshinari Uematsu, Shigeru Takeda, Shoichi Hazama, Shigefumi Yoshino, Keiko Udaka, Hiroto Matsui, Hiroaki Nagano, Yasunari Koki, Shun Doi
Publikováno v:
Journal of Clinical Oncology. 36:e15167-e15167
e15167Background: Based on the exploratory analysis of our previous studies of peptide vaccine, we concluded that the combination of adjuvants hLAG-3Ig + Poly-ICLC is essential for controlling nega...
Autor:
Shun Doi, Yasunari Koki, Masahiro Kitahara, Toshinari Uematsu, Hideki Arima, Hiroto Matsui, Yoshihiro Tokuhisa, Shigefumi Yoshino, Kazuhiko Sakamoto, Keiko Udaka, Shigeru Takeda, Koji Tamada, Shoichi Hazama, Shigeru Yamamoto, Hiroyuki Furukawa, Shinsuke Kanekiyo, Tomoya Miyakawa, Nobuaki Suzuki, Yukio Tokumitsu, Hiroaki Nagano
Publikováno v:
Journal of Clinical Oncology. 35:3086-3086
3086 Background: Based on the exploratory analysis of our previous studies of peptide vaccine, we concluded that the combination of adjuvants hLAG-3Ig + Poly-ICLC is essential for controlling negative immune checkpoints and enhancing the induction of
Publikováno v:
Journal of the Visualization Society of Japan. 20:115-118
We have developed a concurrent visualization system RVSLIB (Real-time Visual Simulation Library). This paper shows the effectiveness of the system when it is applied to large-scale unsteady simulations, for which the conventional post-processing appr