Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Shun Akaeda"'
Autor:
Daiki Hiratsuka, Erika Omura, Chihiro Ishizawa, Rei Iida, Yamato Fukui, Takehiro Hiraoka, Shun Akaeda, Mitsunori Matsuo, Miyuki Harada, Osamu Wada-Hiraike, Yutaka Osuga, Yasushi Hirota
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Adenomyosis is a common gynecological disease in women of reproductive age and causes various symptoms such as dysmenorrhea and heavy menstrual bleeding. However, the influence of pregnancy on the progression of adenomyosis remain
Externí odkaz:
https://doaj.org/article/47e8b6d7a8c14c978564ccec2f43071b
Autor:
Yamato Fukui, Yasushi Hirota, Shizu Aikawa, Akihiko Sakashita, Ryoko Shimizu-Hirota, Norihiko Takeda, Chihiro Ishizawa, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Takehiro Hiraoka, Shun Akaeda, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract Infertility occurs in 15% of couples worldwide. Recurrent implantation failure (RIF) is one of the major problems in in vitro fertilization and embryo transfer (IVF–ET) programs, and how to manage patients with RIF to achieve successful pr
Externí odkaz:
https://doaj.org/article/7a6eca6a7f744b3f90823466c14b402e
Autor:
Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa, Rei IIda, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dyn
Externí odkaz:
https://doaj.org/article/a11915835c324e1caf53642f622ab2eb
Autor:
Yamato Fukui, Yasushi Hirota, Mitsunori Matsuo, Mona Gebril, Shun Akaeda, Takehiro Hiraoka, Yutaka Osuga
Publikováno v:
Reproductive Medicine and Biology, Vol 18, Iss 3, Pp 234-240 (2019)
Abstract Background Recurrent implantation failure is a critical issue in IVF‐ET treatment. Successful embryo implantation needs appropriate molecular and cellular communications between embryo and uterus. Rodent models have been used intensively t
Externí odkaz:
https://doaj.org/article/7e368a7c6c7f4e2faf59e43d2298e226
Autor:
Daiki Hiratsuka, Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Reproductive Sciences. 30:494-525
Under ovarian hormone control, dormant blastocysts obtain implantation capacity (known as blastocyst activation) through their global gene expression. After the activated blastocysts communicate with the receptive uterus, the implantation-competent b
Autor:
Tetsuaki Kaku, Takehiro Hiraoka, Rei Iida, Chihiro Ishizawa, Mitsunori Matsuo, Tomoyuki Hirata, Shizu Aikawa, Yutaka Osuga, Yamato Fukui, Shun Akaeda, Yasushi Hirota
Publikováno v:
Reproductive Sciences. 29:1457-1462
Recurrent implantation failure is a major problem in assisted reproductive technology (ART). Although ART systems have evolved rapidly over the decades, it is still difficult to diagnose uterine conditions suitable for embryo transfer (ET) without th
Autor:
Tomoyuki Fujii, Yutaka Osuga, Yasushi Hirota, Mona Gebril, Norihiko Takeda, Tomoyuki Hirata, Shizu Aikawa, Ryoko Shimizu-Hirota, Yamato Fukui, Takehiro Hiraoka, Shun Akaeda, Hirofumi Haraguchi, Tetsuaki Kaku, Mayuko Saito-Kanatani, Osamu Yoshino, Mitsunori Matsuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of uterine epithelial and stromal STAT3 on embryo implantation have not been elucidated. To ad
Publikováno v:
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY. 36:151-156
Autor:
Takehiro Hiraoka, Yasushi Hirota, Shizu Aikawa, Rei Iida, Chihiro Ishizawa, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Shun Akaeda, Mitsunori Matsuo, Ryoko Shimizu-Hirota, Norihiko Takeda, Yutaka Osuga
Publikováno v:
Endocrinology. 163(5)
Adenomyosis is a benign uterine disease that causes dysmenorrhea, heavy menstrual bleeding, and infertility; however, its pathophysiology remains unclear. Since signal transducer and activator of transcription 3 (STAT3) is crucial for endometrial reg
Autor:
Chihiro Ishizawa, Yasushi Hirota, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Erika Omura, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.).
Levonorgestrel-releasing intrauterine system (LNG-IUS) relieves dysmenorrhea and heavy menstrual bleeding (HMB) in adenomyosis. However, its efficacy on health-related quality of life (HR-QOL) in patients with symptomatic adenomyosis remains unclear.