Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Shun‐Kai Yang"'
Autor:
Chew-Li Moo, Mohd Azuraidi Osman, Shun-Kai Yang, Wai-Sum Yap, Saila Ismail, Swee-Hua-Erin Lim, Chou-Min Chong, Kok-Song Lai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Antimicrobial resistance remains one of the most challenging issues that threatens the health of people around the world. Plant-derived natural compounds have received considerable attention for their potential role to mitigate antibiotic re
Externí odkaz:
https://doaj.org/article/2f6d413735c740c383edb3745ddeae58
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 2, Pp 210-219 (2021)
Mining of plant-derived antimicrobials is the major focus at current to counter antibiotic resistance. This study was conducted to characterize the antimicrobial activity and mode of action of linalyl anthranilate (LNA) against carbapenemase-producin
Externí odkaz:
https://doaj.org/article/35eb1c45c50d44efb443ca93e988b0df
Autor:
Amanda Shen-Yee Kong, Sathiya Maran, Polly Soo-Xi Yap, Swee-Hua Erin Lim, Shun-Kai Yang, Wan-Hee Cheng, Yong-Hui Tan, Kok-Song Lai
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1819 (2022)
The rapid evolution of antimicrobial resistance (AMR) has remained a major public health issue, reducing the efficacy of antibiotics and increasing the difficulty of treating infections. The discovery of novel antimicrobial agents is urgently needed
Externí odkaz:
https://doaj.org/article/2d702dc368a747e48ecd6be7bced51e4
Autor:
Shun-Kai Yang, Ngai-Paing Tan, Chun-Wie Chong, Aisha Abushelaibi, Swee-Hua-Erin Lim, Kok-Song Lai
Publikováno v:
Evolutionary Bioinformatics, Vol 17 (2021)
Antibiotic resistance is a major global health issue that has seen alarming rates of increase in all parts of the world over the past two decades. The surge in antibiotic resistance has resulted in longer hospital stays, higher medical costs, and ele
Externí odkaz:
https://doaj.org/article/a5d01e95dfb94e449a6e6a66b30e3800
Autor:
Shun-Kai Yang, Khatijah Yusoff, Mokrish Ajat, Chien-Yeong Wee, Polly-Soo-Xi Yap, Swee-Hua-Erin Lim, Kok-Song Lai
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Antibiotic–adjuvant combinatory therapy serves as a viable treatment option in addressing antibiotic resistance in the clinical setting. This study was carried out to assess and characterize the adjuvant potential and mode of action of linalool aga
Externí odkaz:
https://doaj.org/article/faeac87f27754fd494534821deba8b86
Autor:
CHEW-LI MOO, SHUN-KAI YANG, MOHD-AZURAIDI OSMAN, MOHD HAFIS YUSWAN, JIUN-YAN LOH, WEI-MENG LIM, SWEE-HUA-ERIN LIM, KOK-SONG LAI
Publikováno v:
Polish Journal of Microbiology, Vol 69, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/50c779b26150404fb05016218edf0070
Autor:
Shun-Kai Yang, Khatijah Yusoff, Mokrish Ajat, Warren Thomas, Aisha Abushelaibi, Riaz Akseer, Swee-Hua Erin Lim, Kok-Song Lai
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214326 (2019)
Klebsiella pneumoniae (KP) remains the most prevalent nosocomial pathogen and carries the carbapenemase (KPC) gene which confers resistance towards carbapenem. Thus, it is necessary to discover novel antimicrobials to address the issue of antimicrobi
Externí odkaz:
https://doaj.org/article/ed2cf96f89cb4d438ef8c1b06541398a
Autor:
Nik Amirah Mahizan, Shun-Kai Yang, Chew-Li Moo, Adelene Ai-Lian Song, Chou-Min Chong, Chun-Wie Chong, Aisha Abushelaibi, Swee-Hua Erin Lim, Kok-Song Lai
Publikováno v:
Molecules, Vol 24, Iss 14, p 2631 (2019)
The evolution of antimicrobial resistance (AMR) in pathogens has prompted extensive research to find alternative therapeutics. Plants rich with natural secondary metabolites are one of the go-to reservoirs for discovery of potential resources to alle
Externí odkaz:
https://doaj.org/article/6d056c3ceb8c44edb6078b0656083657
Autor:
Shun-Kai Yang, Khatijah Yusoff, Chun-Wai Mai, Wei-Meng Lim, Wai-Sum Yap, Swee-Hua Erin Lim, Kok-Song Lai
Publikováno v:
Molecules, Vol 22, Iss 11, p 1733 (2017)
Combinatory therapies have been commonly applied in the clinical setting to tackle multi-drug resistant bacterial infections and these have frequently proven to be effective. Specifically, combinatory therapies resulting in synergistic interactions b
Externí odkaz:
https://doaj.org/article/d93e7962ad4b4e9a90a180a1cb3ee2be
Autor:
Shun Kai Yang, Shintaroh Kubo, Corbin Steven Black, Katya Peri, Daniel Dai, Thibault Legal, Melissa Valente-Paterno, Jacek Gaertig, Khanh Huy Bui
Publikováno v:
eLife, Vol 12 (2024)
Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures suggest that acetylated microtubules are more stable and damage r
Externí odkaz:
https://doaj.org/article/1e787d39768e4dfc864b06fef236b69f