Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shun‐Ai Li"'
Autor:
The Mon La, Hiromi Tachibana, Shun‐Ai Li, Tadashi Abe, Sayaka Seiriki, Hikaru Nagaoka, Eizo Takashima, Tetsuya Takeda, Daisuke Ogawa, Shin‐ichi Makino, Katsuhiko Asanuma, Masami Watanabe, Xuefei Tian, Shuta Ishibe, Ayuko Sakane, Takuya Sasaki, Jun Wada, Kohji Takei, Hiroshi Yamada
Publikováno v:
FASEB Journal. 34(12):16449-16463
Dynamin 1 is a neuronal endocytic protein that participates in vesicle formation by scission of invaginated membranes. Dynamin 1 is also expressed in the kidney; however, its physiological significance to this organ remains unknown. Here, we show tha
Autor:
The Mon La, Hiroshi Yamada, Sayaka Seiriki, Shun-AI Li, Kenshiro Fujise, Natsuho Katsumi, Tadashi Abe, Masami Watanabe, Kohji Takei
Publikováno v:
Cell Structure and Function. 45:121-130
The activity of AMPA-type glutamate receptor is involved in insulin release from pancreatic β-cells. However, the mechanism and dynamics that underlie AMPA receptor-mediated insulin release in β-cells is largely unknown. Here, we show that AMPA ind
Autor:
Peng Huang, Junichiro Futami, Rie Kinoshita, Masakiyo Sakaguchi, Masami Watanabe, Hiromi Kumon, Shun Ai Li
Publikováno v:
Oncology Reports. 33:2908-2914
Reduced expression in immortalized cells (REIC)/Dickkopf (Dkk)-3 is a tumor-suppressor gene and has been studied as a promising therapeutic gene for cancer gene therapy. Intratumoral injection of an adenovirus vector carrying the human REIC/Dkk-3 gen
Autor:
Yasuyuki Kobayashi, Shun Ai Li, Masami Watanabe, Koichiro Wada, Yasutomo Nasu, Motoo Araki, Kazuhiko Ochiai, Yuichi Ariyoshi, Takuya Sadahira, Yuhei Horikawa
Our group previously developed an adenoviral vector encoding the REIC/Dkk-3 gene (Ad-REIC), a tumor suppressor, for cancer gene therapy. The Ad-REIC agent induces apoptosis and inhibits invasion in a number of cancer cell lines; however, the molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91176580693547384f0f225ee53c9b4a
https://ousar.lib.okayama-u.ac.jp/55505
https://ousar.lib.okayama-u.ac.jp/55505
Autor:
Kohji Takei, Tadashi Abe, Naohisa Ogo, Akira Asai, Peng Huang, Masami Watanabe, Shota Tago, Hiroshi Yamada, Shun Ai Li, Satoru Ikeda
Publikováno v:
Biochemical and Biophysical Research Communications. 443:511-517
Dynasore, a specific dynamin GTPase inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments. In search for novel dynamin inhibitors that suppress actin dynamics more efficiently, dynasore analogues were
Autor:
Ryuta Tanimoto, Yuichi Ariyoshi, Shun Ai Li, Kazuhiko Ochiai, Hiromi Kumon, Masami Watanabe, Hideo Ueki, Haruki Kaku, Yasutomo Nasu, Nam Ho Huh, Junichiro Futami, Shin Ebara, Peng Huang, Rie Kinoshita, Masakiyo Sakaguchi
Publikováno v:
Oncology Reports
Gene expression systems with various promoters, including the cytomegalovirus (CMV) promoter, have been developed to increase the gene expression in a variety of normal and cancer cells. In particular, in the clinical trials of cancer gene therapy, a
Publikováno v:
Cell Structure and Function. 36:145-154
Dynamin, a ~100 kDa large GTPase, is known as a key player for membrane traffic. Recent evidence shows that dynamin also regulates the dynamic instability of microtubules by a mechanism independent of membrane traffic. As microtubules are highly dyna
Autor:
Yuki Masuoka, Shun Ai Li, Tadashi Abe, Hiromi Kumon, Mihoko Isoda, Hiroshi Yamada, Akira Asai, Yasutomo Nasu, Kohji Takei, Masami Watanabe
Publikováno v:
Biochemical and Biophysical Research Communications. 390:1142-1148
Dynamic remodeling of actin filaments are bases for a variety of cellular events including cell motility and cancer invasion, and the regulation of actin dynamics implies dynamin, well characterized endocytotic protein. Here we report that dynasore,
Autor:
Yasufumi Sato, Xiao Jian Han, Taku Kaitsuka, Angus C. Nairn, Hideki Matsui, Yun Fei Lu, Shun Ai Li, Kohji Takei, Masayuki Matsushita, Kazuhito Tomizawa
Publikováno v:
The Journal of Cell Biology
Mitochondria are dynamic organelles that frequently move, divide, and fuse with one another to maintain their architecture and functions. However, the signaling mechanisms involved in these processes are still not well characterized. In this study, w
Autor:
Kazuhiro Omori, Mayumi Yamaguchi-Morimoto, Kaori Matsuura, Tomoko Yamaguchi, Koji Naruishi, Hideo Arai, Shogo Takashiba, Shun Ai Li, Kohji Takei
Publikováno v:
Cell and Tissue Research. 330:75-82
Cyclosporin A (CsA) is an immunosuppressant with severe side effects including gingival overgrowth. We have previously reported that CsA impairs the activity of the lysosomal enzymes cathepsin B and L in human gingival fibroblasts (HGFs). Here, we ha