Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shumpei Mizuta"'
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 543-544 (2022)
Externí odkaz:
https://doaj.org/article/fc865730a5d34cf98fbfa3e3ca2e1000
Autor:
Takao Komai, Kuniaki Tanaka, Toshiro Maihara, Seiji Okamoto, Kenichiro Kobayashi, Atsuko Ikegawa, Ritsuko Kitamura, Noriko Yamane, Toshio Heike, Chieko Matsushima, Takahito Wada, Tadamori Takahara, Atushi Yoshida, Yoshinobu Nishida, Atsushi Iwai, Saya Mononobe, Shumpei Mizuta, Ikuya Usami, Asami Watanabe
Publikováno v:
International Journal of Laboratory Hematology. 44:349-355
Introduction GATA1 mutation plays an important role in initiating transient abnormal myelopoiesis (TAM) and in the clonal evolution towards acute megakaryoblastic leukaemia (AMKL) associated with Down syndrome (DS). This study aimed to develop and va
Autor:
Yusuke Koba, Akira Tamekane, Takahito Kawata, Takao Komai, Noriko Yamane, Naoya Ukyo, Saya Mononobe, Shumpei Mizuta, Mitsumasa Watanabe
Publikováno v:
American Journal of Clinical Pathology. 154:236-241
Objectives C-C chemokine receptor type 4 (CCR4) proteins are expressed on the neoplastic cells of adult T-cell leukemia/lymphoma (ATLL). As the mutation status of CCR4 gene is reported to correlate with significant clinical information such as progno
Autor:
Naoya Ukyo, Takao Komai, Akira Tamekane, Yusuke Koba, Noriko Yamane, Mitsumasa Watanabe, Shumpei Mizuta, Saya Mononobe, Takahito Kawata, Hiroshi Kawabata
Publikováno v:
International Journal of Hematology. 110:322-330
The development of effective therapies has enabled long-term survival for many patients with multiple myeloma (MM). However, the administration of antibody drugs, such as daratumumab, which bind to plasma cell (PC) surface proteins, may prevent PC de
Autor:
Yusuke Koba, Akira Tamekane, Saya Mononobe, Shumpei Mizuta, Takao Komai, Shinichiro Matsuki, Noriko Yamane, Mitsumasa Watanabe, Sachiko Mitani, Asami Watanabe, Takahito Kawata
Publikováno v:
Cytometry. Part B, Clinical cytometryREFERENCES. 102(1)
Background Multi-parametric flow cytometry (MFC) is a helpful tool for detecting neoplastic cells in malignant lymphoma; however, lymphoma cells can be difficult to detect when characteristic immunophenotypic abnormalities are not evident. We evaluat
Autor:
Noriko Yamane, Toshiro Maihara, Toshio Heike, Takayuki Hamabata, Shumpei Mizuta, Ikuya Usami, Kenichiro Kobayashi
Publikováno v:
Journal of pediatric hematology/oncology. 43(2)
Secondary expansion and/or evolution of aggressive subclones are associated with the disease progression and resistance to chemotherapy in neuroblastoma, and it is important to track the clonal changes during the treatment period. Cell-free (cf) DNA
Autor:
Noriko Yamane, Akira Tamekane, Takao Komai, Yusuke Koba, Naoya Ukyo, Shumpei Mizuta, Takahito Kawata, Mitsumasa Watanabe
Publikováno v:
International journal of laboratory hematologyREFERENCES. 41(5)
Introduction Acute myeloid leukemia (AML) is a heterogeneous disease associated with various genetic abnormalities. Somatic mutations in nucleophosmin 1 (NPM1), fms-related tyrosine kinase 3 (FLT3), and DNA methyltransferase 3 alpha (DNMT3A) are the
Autor:
Shumpei Mizuta, Yusuke Koba, Naoya Ukyo, Akira Tamekane, Takao Komai, Noriko Yamane, Mitsumasa Watanabe
Publikováno v:
Laboratory medicine. 50(3)
Background SF3B1 (splicing factor 3B subunit-1) somatic mutation is specifically detected in myelodysplastic syndrome (MDS) with ring sideroblasts (MDS-RS). We investigated the sensitivity and utility of SF3B1 mutation analysis as a clinical laborato
Autor:
Robert G. Roeder, Chihiro Kaminaga, Kasumi Oda, Norinaga Urahama, Haruka Fujita, Asami Kawai, Natsumi Hasegawa, Keiji Matsui, Ruri Ishino, Mitsuhiro Ito, Shumpei Mizuta, Azusa Fujita, Tomoya Minami
Publikováno v:
Genes to Cells. 19:28-51
The MED1 subunit of the Mediator transcriptional coregulator complex coactivates GATA1 and induces erythropoiesis. Here, we show the dual mechanism of GATA1- and MED1-mediated transcription. MED1 expression levels in K562 erythroleukemia cells parall
Autor:
Norinaga Urahama, Robert G. Roeder, Shumpei Mizuta, Ruri Ishino, Keiji Matsui, Kasumi Oda, Natsumi Hasegawa, Mitsuhiro Ito
Publikováno v:
Biochemical and Biophysical Research Communications. 440:184-189
The MED1 subunit of the Mediator transcriptional coregulator complex is a nuclear receptor-specific coactivator. A negative feedback mechanism of thyroid-stimulating hormone (TSH, or thyrotropin) expression in the thyrotroph in the presence of triiod