Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shumeng Ma"'
Autor:
Wolfgang Knecht, S. Zoë Fisher, Jiaqi Lou, Céleste Sele, Shumeng Ma, Anna Andersson Rasmussen, Nikos Pinotsis, Frank Kozielski
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13649 (2023)
The β-coronavirus family, encompassing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Severe Acute Respiratory Syndrome Coronavirus (SARS), and Middle East Respiratory Syndrome Coronavirus (MERS), has triggered pandemics within the la
Externí odkaz:
https://doaj.org/article/3053d2a147a84cf6b0ab76f0545180b8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11197 (2023)
The identification of multiple simultaneous orientations of small molecule inhibitors binding to a protein target is a common challenge. It has recently been reported that the conformational heterogeneity of ligands is widely underreported in the Pro
Externí odkaz:
https://doaj.org/article/8f2b6e741dd74d9989c221c960d6629a
Autor:
Alberto Borsatto, Obaeda Akkad, Ioannis Galdadas, Shumeng Ma, Shymaa Damfo, Shozeb Haider, Frank Kozielski, Carolina Estarellas, Francesco Luigi Gervasio
Publikováno v:
eLife, Vol 11 (2022)
Non-structural protein 1 (Nsp1) is a main pathogenicity factor of α- and β-coronaviruses. Nsp1 of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppresses the host gene expression by sterically blocking 40S host ribosomal subunits an
Externí odkaz:
https://doaj.org/article/bb41995f76cd4784b965708fe465be40
Autor:
Shumeng Ma, Shymaa Damfo, Jiaqi Lou, Nikos Pinotsis, Matthew W. Bowler, Shozeb Haider, Frank Kozielski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12448 (2022)
The regular reappearance of coronavirus (CoV) outbreaks over the past 20 years has caused significant health consequences and financial burdens worldwide. The most recent and still ongoing novel CoV pandemic, caused by Severe Acute Respiratory Syndro
Externí odkaz:
https://doaj.org/article/a2cbfefdbcc24833810fec21fce9177f
Autor:
Alberto Borsatto, Obaeda Akkad, Ioannis Galdadas, Shumeng Ma, Shymaa Damfo, Shozeb Haider, Frank Kozielski, Carolina Estarellas, Francesco Luigi Gervasio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822c0f6eed5b5410272ee6471e6c4c51
https://doi.org/10.7554/elife.81167.sa2
https://doi.org/10.7554/elife.81167.sa2
Autor:
Weiwei Gao, Xuemei Deng, Xiaodong Wang, Zhao Li, Shumeng Ma, Fei Cao, Tao Shi, Hui-Hong Wang, Zhen Wang
Publikováno v:
Organic Chemistry Frontiers. 8:82-86
An unprecedented palladium(II)-catalyzed ortho-alkylation of N-methoxybenzamide with epoxides has been applied to the total synthesis of the isochroman natural product (–)-berkelic acid. Combining this strategy with a well documented spiroacetaliza
Autor:
Borsatto, Alberto, Akkad, Obaeda, Galdadas, Ioannis, Shumeng Ma, Damfo, Shymaa, Haider, Shozeb, Kozielski, Frank, Estarellas, Carolina, Gervasio, Francesco Luigi
Publikováno v:
eLife; 11/22/2022, p1-25, 25p
Autor:
Yan Liang, Jinhong Chen, Xiaoling Hu, Shumeng Ma, Tao Shi, Xiaohong Fan, Zhen Wang, Junfang Li, Xiangyong Hao, Longqing Zhu
Publikováno v:
Bioorganicmedicinal chemistry letters. 44
Inflammation as a host’s excessive immune response to stimulation, is involved in the development of numerous diseases. To discover novel anti-inflammatory agents and based on our previous synthetic work on marine natural product Chrysamide B, it a
Autor:
Shumeng Ma, Tian Luo, Ziyi Liang, Longqing Zhu, Xiaoling Hu, Wen Tan, Xiaohong Fan, Tao Shi, Zhen Wang, Dan Liu
Publikováno v:
European journal of medicinal chemistry. 211
The combination between two well-studied bioactive compounds melatonin and salicylic acid with proper modifications unexpectedly creates a sharp pair of “scissors” cutting off the vicious connection between inflammation and cancer by targeting a
Autor:
Yan Liang, Jian Zhang, Jiedan Deng, Yingmei Lu, Shumeng Ma, Junfang Li, Tao Shi, Zhen Wang, Wen Tan, Xiaohong Fan
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115526
A series of 1,3-benzothiazinone derivatives were designed and synthesized for pharmacological assessments. Among the synthesized 19 compounds, some compounds showed high activities on inhibiting LPS-induced nitrite oxide and TNF-α production, down-r