Nonsteroidal anti-inflammatory drugs as potential ecto-nucleotide phosphodiesterase inhibitors

Autor: Shumaila Tasneem, Muhammad Saleem, Sheikh Arshad Saeed

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)

Phosphodiesterases (PDE) are group of enzymes which catalyze the hydrolysis of cAMP and cGMP. Since these cyclic phosphate moieties worked as intracellular second messengers in numerous physiological processes, their inhibition can affect normal phys

Externí odkaz: https://doaj.org/article/50616d50f7354fcd830da30e5fbfd635

Lignans from Tujia Ethnomedicine Heilaohu: Chemical Characterization and Evaluation of Their Cytotoxicity and Antioxidant Activities

Autor: Yongbei Liu, Yupei Yang, Shumaila Tasneem, Nusrat Hussain, Muhammad Daniyal, Hanwen Yuan, Qingling Xie, Bin Liu, Jing Sun, Yuqing Jian, Bin Li, Shenghuang Chen, Wei Wang

Publikováno v: Molecules, Vol 23, Iss 9, p 2147 (2018)

Heilaohu, the roots of Kadsura coccinea, has a long history of use in Tujia ethnomedicine for the treatment of rheumatoid arthritis and gastroenteric disorders, and a lot of work has been done in order to know the material basis of its pharmacologica

Externí odkaz: https://doaj.org/article/22f2ad18632d44c4ac8067c16915d38d

Cytotoxicity of Schisandronic Acid from Kadsura coccinea by Activation of Caspase-3, Cleavage of poly-ADP Ribose Polymerase, and Reduction of Oxidative Stress

Autor: Shumaila Tasneem, Bin Liu, Yupei Yang, M. Iqbal Choudhary, Wei Wang

Publikováno v: Revista Brasileira de Farmacognosia. 31:51-58

Breast cancer is an invasive malignant neoplasm; however, an increasing number of naturally occurring chemical compounds have been identified as potent cytotoxic agents. Kadsura coccinea (Lem.) A.C.Sm., Schisandraceae, is a medicinally important Chin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a75034126a0eaf0a76132fa8d8bcd84
https://doi.org/10.1007/s43450-021-00136-7

Nonsteroidal anti-inflammatory drugs as potential ecto-nucleotide phosphodiesterase inhibitors

Autor: Sheikh Arshad Saeed, Muhammad Asad Saleem, Shumaila Tasneem

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e18271, Published: 16 MAR 2020
Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e18271
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e18271
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP

Phosphodiesterases (PDE) are group of enzymes which catalyze the hydrolysis of cAMP and cGMP. Since these cyclic phosphate moieties worked as intracellular second messengers in numerous physiological processes, their inhibition can affect normal phys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1c5b89e4320ea02e27f1c490188842
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100531&lng=en&tlng=en

Chemical characterization of constituents from

Autor: Ting, Zeng, Yan-Ran, Tang, Bin, Li, Shumaila, Tasneem, Han-Wen, Yuan, Yan-Zhe, Jia, Muhammad, Daniyal, Nusrat, Hussain, Wen-Miao, Wang, Da-Lei, Zuo, Li-Min, Gong, Bin, Liu, Ji-Lian, Shi, Zhun, Zhou, Cai-Yun, Peng, Shu-Jin, He, Wei, Wang

Publikováno v: Natural product research. 34(17)

Twenty-four compounds were isolated from the roots of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::172d88a0f4cfa8e6eea93eed1d262e7a
https://pubmed.ncbi.nlm.nih.gov/30582363