Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shule Hou"'
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102472- (2022)
Age-related hearing loss (ARHL) is the most prevalent sensory disorder in the elderly. Currently, no treatment can effectively prevent or reverse ARHL. Aging auditory organs are often accompanied by exacerbated oxidative stress and metabolic deterior
Externí odkaz:
https://doaj.org/article/705d20663a664000af36c3e3b36fa603
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Hereditary deafness is one of the most common human birth defects. GJB2 gene mutation is the most genetic etiology. Gap junction protein 26 (connexin26, Cx26) encoded by the GJB2 gene, which is responsible for intercellular substance transfer and sig
Externí odkaz:
https://doaj.org/article/02063b04d1534b059568bc76c2038346
Autor:
Shule Hou, Jifang Zhang, Yan Wu, Chen Junmin, Huang Yuyu, Baihui He, Yan Yang, Yuren Hong, Jiarui Chen, Jun Yang, Shuna Li
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Ribbon synapses are important structures in transmitting auditory signals from the inner hair cells (IHCs) to their corresponding spiral ganglion neurons (SGNs). Over the last few decades, deafness has been primarily attributed to the deterioration o
Externí odkaz:
https://doaj.org/article/08604d2566d94c3a8691afb483721ce1
Autor:
Lianhua Sun, Dekun Gao, Junmin Chen, Shule Hou, Yue Li, Yuyu Huang, Fabio Mammano, Jianyong Chen, Jun Yang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Mutations in the GJB2 gene that encodes connexin 26 (Cx26) are the predominant cause of prelingual hereditary deafness, and the most frequently encountered variants cause complete loss of protein function. To investigate how Cx26 deficiency induces d
Externí odkaz:
https://doaj.org/article/5d32b36ce3f94bc6aadf20dc53d62ebd
Autor:
Jianyong Chen, Dekun Gao, Junmin Chen, Shule Hou, Baihui He, Yue Li, Shuna Li, Fan Zhang, Xiayu Sun, Yulian Jin, Lianhua Sun, Jun Yang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The hair cells of the cochlea play a decisive role in the process of hearing damage and recovery, yet knowledge of their regeneration process is still limited. Greater epithelial ridge (GER) cells, a type of cell present during cochlear development t
Externí odkaz:
https://doaj.org/article/7fb52564919d4d02a7d1b583dd32e9e9
Autor:
Junmin Chen, Penghui Chen, Baihui He, Tianyu Gong, Yue Li, Jifang Zhang, Jingrong Lv, Fabio Mammano, Shule Hou, Jun Yang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
GJB2 and GJB6 are adjacent genes encoding connexin 26 (Cx26) and connexin 30 (Cx30), respectively, with overlapping expressions in the inner ear. Both genes are associated with the commonest monogenic hearing disorder, recessive isolated deafness DFN
Externí odkaz:
https://doaj.org/article/0b3036c9c4944e3d9d4d76025f2597bf
Autor:
Jianyong Chen, Dekun Gao, Junmin Chen, Shule Hou, Baihui He, Yue Li, Shuna Li, Fan Zhang, Xiayu Sun, Fabio Mammano, Lianhua Sun, Jun Yang, Guiliang Zheng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Greater epithelial ridge cells, a transient neonatal cell group in the cochlear duct, which plays a crucial role in the functional maturation of hair cell, structural development of tectorial membrane, and refinement of audio localization before hear
Externí odkaz:
https://doaj.org/article/5b4697d8e4374c9b949902a3a9fe5d0f
Autor:
Shule Hou, Penghui Chen, Jiarui Chen, Junmin Chen, Lianhua Sun, Jianyong Chen, Baihui He, Yue Li, Huan Qin, Yuren Hong, Shuna Li, Jingchun He, Dekun Gao, Fabio Mammano, Jun Yang
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
Autophagy and apoptosis have a complex interplay in the early embryo development. The development of spiral ganglion neurons (SGNs) in addition to Corti’s organ in the mammalian cochlea remains crucial in the first two-week postnatal period. To inv
Externí odkaz:
https://doaj.org/article/018c9e951bd145498b7dfdc3a805a3a1
Publikováno v:
Frontiers in Pediatrics, Vol 7 (2019)
Background: To reduce surgical complications and avoid lifelong thyroid hormone replacement, hemithyroidectomy is preferred in children and adolescents with benign nodular thyroid disease. However, hypothyroidism following hemithyroidectomy may occur
Externí odkaz:
https://doaj.org/article/fb596b18872f4f3fb9e4fbd39965b29c
Publikováno v:
European Journal of Histochemistry, Vol 63, Iss 2 (2019)
The Kölliker’s organ is a transient epithelial structure during cochlea development that gradually degenerates and disappears at postnatal 12-14 days (P12-14). While apoptosis has been shown to play an essential role in the degeneration of the Kö
Externí odkaz:
https://doaj.org/article/446aef32ff2f42439a899fbfb13983a2