Zobrazeno 1 - 10
of 3 087
pro vyhledávání: '"Shuldiner A"'
Autor:
Mihail Halachev, Viktoria-Eleni Gountouna, Alison Meynert, Gannie Tzoneva, Alan R. Shuldiner, Colin A. Semple, James F. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract It is unclear how patterns of regional genetic differentiation in the UK and Ireland might impact the protein-coding fraction of the genome. We exploit UK Biobank (UKB) and Viking Genes whole exome sequencing data to study regional genetic d
Externí odkaz:
https://doaj.org/article/a83a3ee794774ee0b9a9a70a69d6acce
Autor:
Jennifer Shuldiner, Meagan Lacroix, Marianne Saragosa, Catherine Reis, Kevin L. Schwartz, Sharon Gushue, Valerie Leung, Jeremy Grimshaw, Michael Silverman, Kednapa Thavorn, Jerome A. Leis, Michael Kidd, Nick Daneman, Mina Tradous, Bradley Langford, Andrew M. Morris, Jonathan Lam, Gary Garber, Jamie Brehaut, Monica Taljaard, Michelle Greiver, Noah Michael Ivers
Publikováno v:
Implementation Science, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Unnecessary antibiotic prescriptions in primary care are common and contribute to antimicrobial resistance in the population. Audit and feedback (A&F) on antibiotic prescribing to primary care can improve the appropriateness of an
Externí odkaz:
https://doaj.org/article/ba469a9457c94237849a68d2f6b4dcb7
Autor:
Aysegul Guvenek, Neelroop Parikshak, Daria Zamolodchikov, Sahar Gelfman, Arden Moscati, Lee Dobbyn, Eli Stahl, Alan Shuldiner, Giovanni Coppola
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Microglia are the resident immune cells of the central nervous system and are involved in brain development, homeostasis, and disease. New imaging and genomics technologies are revealing microglial complexity across developmental and functio
Externí odkaz:
https://doaj.org/article/db54ef0641f24ba999c630d873047935
Autor:
Juan Lorenzo Rodriguez-Flores, Shareef Khalid, Neelroop Parikshak, Asif Rasheed, Bin Ye, Manav Kapoor, Joshua Backman, Farshid Sepehrband, Silvio Alessandro Di Gioia, Sahar Gelfman, Tanima De, Nilanjana Banerjee, Deepika Sharma, Hector Martinez, Sofia Castaneda, David D’Ambrosio, Xingmin A. Zhang, Pengcheng Xun, Ellen Tsai, I-Chun Tsai, Regeneron Genetics Center, Maleeha Zaman Khan, Muhammad Jahanzaib, Muhammad Rehan Mian, Muhammad Bilal Liaqat, Khalid Mahmood, Tanvir Us Salam, Muhammad Hussain, Javed Iqbal, Faizan Aslam, Michael N. Cantor, Gannie Tzoneva, John Overton, Jonathan Marchini, Jeffrey G. Reid, Aris Baras, Niek Verweij, Luca A. Lotta, Giovanni Coppola, Katia Karalis, Aris Economides, Sergio Fazio, Wolfgang Liedtke, John Danesh, Ayeesha Kamal, Philippe Frossard, Thomas Coleman, Alan R. Shuldiner, Danish Saleheen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The genetic factors of stroke in South Asians are largely unexplored. Exome-wide sequencing and association analysis (ExWAS) in 75 K Pakistanis identified NM_000435.3(NOTCH3):c.3691 C > T, encoding the missense amino acid substitution p.Arg1
Externí odkaz:
https://doaj.org/article/6deb4ea097ec40d293f51e257ce35689
Autor:
Shuldiner, Jennifer1,2 (AUTHOR) Jennifer.shuldiner@wchospital.ca, Lacroix, Meagan1 (AUTHOR), Saragosa, Marianne3 (AUTHOR), Reis, Catherine4 (AUTHOR), Schwartz, Kevin L.5,6,7,8 (AUTHOR), Gushue, Sharon9 (AUTHOR), Leung, Valerie7,10,11 (AUTHOR), Grimshaw, Jeremy12 (AUTHOR), Silverman, Michael13 (AUTHOR), Thavorn, Kednapa12 (AUTHOR), Leis, Jerome A.14 (AUTHOR), Kidd, Michael15,16,17 (AUTHOR), Daneman, Nick5,7,18,19 (AUTHOR), Tradous, Mina1,20 (AUTHOR), Langford, Bradley7 (AUTHOR), Morris, Andrew M.21 (AUTHOR), Lam, Jonathan22 (AUTHOR), Garber, Gary23,24 (AUTHOR), Brehaut, Jamie12 (AUTHOR), Taljaard, Monica12 (AUTHOR)
Publikováno v:
Implementation Science. 9/16/2024, Vol. 19 Issue 1, p1-15. 15p.
Autor:
Shuldiner, Pavel, Oldford, R. Wayne
Motivated by an approach to visualization of high dimensional statistical data given in Hurley and Oldford (2011), this work examines the clique structure of $J_n(m, m-1)$ Johnson graphs. Cliques and maximal cliques are characterized and proved to be
Externí odkaz:
http://arxiv.org/abs/2208.12710
Autor:
Jennifer Shuldiner, Emily Lam, Nida Shah, Jeremy Grimshaw, Laura Desveaux, Ruth Heisey, Michael S. Taccone, Monica Taljaard, Kednapa Thavorn, David Hodgson, Sumit Gupta, Aisha Lofters, Noah Ivers, Paul C. Nathan
Publikováno v:
Implementation Science, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Childhood cancer treatment while often curative, leads to elevated risks of morbidity and mortality. Survivors require lifelong periodic surveillance for late effects of treatment, yet adherence to guideline-recommended tests is s
Externí odkaz:
https://doaj.org/article/9ac02674bed3470dac459bfe4e7109b7
Autor:
Shuldiner, Pavel, Oldford, R. Wayne
This work examines the problem of clique enumeration on a graph by exploiting its clique covers. The principle of inclusion/exclusion is applied to determine the number of cliques of size $r$ in the graph union of a set $\mathcal{C} = \{c_1, \ldots,
Externí odkaz:
http://arxiv.org/abs/2206.14895
Autor:
Amber L. Beitelshees, Elizabeth A. Streeten, Zhinous Shahidzadeh Yazdi, Hilary B. Whitlatch, Braxton D. Mitchell, Alan R. Shuldiner, May E. Montasser, Simeon I. Taylor
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract DPP4 inhibitors are widely prescribed as treatments for type 2 diabetes. Because drug responses vary among individuals, we initiated investigations to identify genetic variants associated with the magnitude of drug responses. Sitagliptin (10
Externí odkaz:
https://doaj.org/article/b3cad01e7001482bb125303fa5d0bad4
Autor:
Shuldiner, Pavel, Oldford, R. W.
A novel multinomial theorem for commutative idempotents is shown to lead to new results about the moments, central moments, factorial moments, and their generating functions for any random variable $X = \sum_{i} Y_i $ expressible as a sum of Bernoull
Externí odkaz:
http://arxiv.org/abs/2110.02363