Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shula Radin"'
Autor:
Paul Ducheyne, Shula Radin, C. Knabe, Jonathan P. Garino, Thomas P. Schaer, Haibo Qu, Megan Burke
Publikováno v:
Military Medicine. 179:29-33
Orthopedic injuries constitute the majority of wounds sustained by U.S. soldiers in recent conflicts. The risk of infection is considerable with fracture fixation devices. In this pilot study, we examined the use of unique bactericidal micron-thin so
Autor:
Paul Ducheyne, Terry A. Freeman, Payal Patal, Valentin Antoci, Javad Parvizi, Gerald Harrison, Shula Radin, Noreen J. Hickok, Christopher S. Adams, Irving M. Shapiro
Publikováno v:
Journal of Orthopaedic Research. 27:701-709
Peri-prosthetic infection remains a serious complication of joint replacement surgery. Herein, we demonstrate that a vancomycin-containing sol-gel film on Ti alloy rods can successfully treat bacterial infections in an animal model. The vancomycin-co
Publikováno v:
Biomaterials. 28:4091-4097
Bioactive glass is used as both a bone filler and as a coating on implants, and has been advocated as a potential osteogenic scaffold for tissue engineering. Rat derived mesenchymal stem cells (MSCs) show elevated levels of levels of alkaline phospha
Autor:
Paul Ducheyne, Shula Radin
Publikováno v:
Biomaterials. 28:1721-1729
Risk of infection is considerable in open fractures and its management is challenging, especially when fracture fixation material is used. Thus, it may be desirable to use a device from which antibiotics can be released in a controlled way. Room temp
Publikováno v:
Key Engineering Materials. :1025-1028
Controlled release silica sol-gels are room temperature processed, porous, resorbable, and biocompatible materials. Many molecules including drugs, proteins, and growth factors can be released from sol-gels, and the quantity and duration of the relea
Autor:
Valentin Antoci, Javad Parvizi, Irving M. Shapiro, Christopher S. Adams, Shula Radin, Paul Ducheyne, Noreen J. Hickok
Publikováno v:
Key Engineering Materials. :1323-1326
Beneficial properties of room temperature processed silica sol-gels as resorbable and biocompatible materials for the controlled release of drugs and macromolecules have been described before. Recently, it was shown that a thin sol-gel film can be us
Publikováno v:
Biomaterials. 62
Risk of infection is considerable in open fractures, especially when fracture fixation devices are used to stabilize the fractured bones. Overall deep infection rates of 16.2% have been reported. The infection rate is even greater, up to 32.2%, with
Publikováno v:
Key Engineering Materials. :759-762
Previously, the properties of room temperature processed silica sol gel (also called xerogels) as resorbable and biocompatible controlled release systems were described. It was demonstrated that drugs and macromolecules with a variety of properties a
Publikováno v:
Biomaterials. 26:1935-1943
Tissue engineering offers a promising new approach to bone tissue grafting. One material that has received attention in this regard is the polymer poly (lactic-co-glycolic acid) (PLGA). It has the advantage of controllable bioresorption and ease of p
Publikováno v:
Key Engineering Materials. :619-622
A previous study demonstrated that the incorporation of bioactive glass (BG) into poly (lactic-co-glycolic acid) (PLGA) can promote the osteoblastic differentiation of marrow stromal cells (MSC) on PLGA by forming a calcium phosphate rich layer on it