Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shuklendu D. Karyakarte"'
Publikováno v:
Organic Reactions. :421-769
Autor:
Nathaniel J. Moorman, Nikhil Madadi, Daniel N. Streblow, Nicole N. Haese, Robert Bostwick, Mark T. Heise, Wes Sanders, Theresa H Nguyen, Corinne E. Augelli-Szafran, Nichole A Towers, Omar Moukha-Chafiq, Victor R. DeFilippis, Joseph A. Maddry, Sixue Zhang, Ashish K. Pathak, Mark J. Suto, Subramaniam Ananthan, Sharon Taft-Benz, Lynn Rasmussen, Shuklendu D Karyakarte, Michael Denton, Nicholas A May, Kevin J Rodzinak, Aaron D Streblow, Thomas E. Morrison
Publikováno v:
Antimicrob Agents Chemother
Venezuelan equine encephalitis virus (VEEV) is a reemerging alphavirus that can cause encephalitis resulting in severe human morbidity and mortality. Using a high-throughput cell-based screen, we identified a quinolinone compound that protected again
Publikováno v:
Chem Commun (Camb)
Bridged bicyclic ketals display a range of bioactivities. Their catalytic enantioselective synthesis from achiral, acyclic 1,1-disubstituted alkene diols is disclosed. This reaction combines asymmetric catalysis with a distal radical migration. Alkyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de693935dc3427d5bb7ffdadc4c0b9d
https://europepmc.org/articles/PMC8018521/
https://europepmc.org/articles/PMC8018521/
Publikováno v:
The Journal of Organic Chemistry. 82:11311-11325
This Perspective describes the development of a family of copper(II)-catalyzed alkene difunctionalization reactions that enable stereoselective addition of amine derivatives and alcohols onto pendant unactivated alkenes to provide a range of valuable
Autor:
Joshua D. Sieber, Bo Qu, Heewon Lee, Olga V. Zatolochnaya, Nizar Haddad, Jean-Nicolas Desrosiers, Ling Wu, Soumik Biswas, Chris H. Senanayake, Guisheng Li, Nathan K. Yee, Nelu Grinberg, Xiao-Jun Wang, Daniel R. Fandrick, Daniel Rivalti, Sonia Rodriguez, Hari P. R. Mangunuru, Shuklendu D. Karyakarte, Jinhua J. Song
Publikováno v:
Organic letters. 20(7)
Novel bidentate phosphine ligands BABIPhos featuring a biaryl bis-dihydrobenzooxaphosphole core are presented. Their synthesis was achieved via Pd-catalyzed reductive homocoupling of dihydrobenzooxaphosphole aryl triflates. An efficient route toward
Autor:
Keith R. Fandrick, Daniel Rivalti, Nizar Haddad, Marisa C. Kozlowski, Olga V. Zatolochnaya, Suttipol Radomkit, Scott Pennino, Nathan K. Yee, Keith McKellop, Dmitry Kurouski, Jean-Nicolas Desrosiers, Heewon Lee, Chris H. Senanayake, Soumik Biswas, Shuklendu D. Karyakarte, Jinhua J. Song, Bo Qu, Sonia Rodriguez, Hari P. R. Mangunuru, Sergei Tcyrulnikov, Joshua D. Sieber
Enantioselective synthesis of α-aryl and α-heteroaryl piperidines is reported. The key step is an iridium-catalyzed asymmetric hydrogenation of substituted N-benzyl pyridinium salts. High levels of enantioselectivity up to 99.3:0.7 er were obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea58d5693fceeb4c744ba3de80f4c7e0
https://europepmc.org/articles/PMC5835364/
https://europepmc.org/articles/PMC5835364/
Publikováno v:
The Journal of Organic Chemistry. 77:7755-7760
Isoxazolidines are useful in organic synthesis, drug discovery, and chemical biology endeavors. A new stereoselective synthesis of methyleneoxy-substituted isoxazolidines is disclosed. The method involves copper-catalyzed aminooxygenation/cyclization
Autor:
Josiah P. Matthew, Shuklendu D. Karyakarte, Fatima C. Sequeira, Garrick H. Zibreg, Sherry R. Chemler, Marina M.M. Ferreira, Guoqing Huang
Publikováno v:
ChemInform. 46
A new method for the synthesis of 2-aminomethyl functionalized 1,4-benzodiazepin-5-ones is presented. The benzodiazepine core is well-known to interact with biological receptors and many pharmaceutical drugs are derived from this structure. The alken
Autor:
Josiah P. Matthew, Fatima C. Sequeira, Marina M.M. Ferreira, Sherry R. Chemler, Garrick H. Zibreg, Guoqing Huang, Shuklendu D. Karyakarte
Publikováno v:
Tetrahedron letters. 56(23)
A new method for the synthesis of 2-aminomethyl functionalized 1,4-benzodiazepin-5-ones is presented. The benzodiazepine core is well-known to interact with biological receptors and many pharmaceutical drugs are derived from this structure. The alken
Publikováno v:
ChemInform. 43
Cu-catalyzed treatment of butenylated hydroxylamines with the radical (II) allows a new and stereoselective access to isoxazolidines.