Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shukai Xia"'
Autor:
Michael B. Murphy, Laura Vitale, Shukai Xia, Zeyu Peng, Thomas O’Neill, Jay Lillquist, Anna Wasiuk, Jeff Weidlick, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Colleen Patterson, James Boyer, April R. Baronas, Mingjiu Chen, Hugh M. Davis, Mark Ma, Joel Goldstein, Lawrence J. Thomas, Diego Alvarado, Henry C. Marsh, Tibor Keler
Publikováno v:
Immuno, Vol 3, Iss 3, Pp 273-288 (2023)
Immunoglobulin-like transcript 4 (ILT4) is an immunosuppressive molecule predominantly expressed on myeloid cells. Recent studies combining ILT4 suppression with programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) blockade have show
Externí odkaz:
https://doaj.org/article/e24496d39a404eb1a00b6ba38c57bbb8
Autor:
Hongyan Li, Zemeng Ma, Xiaoyao Hao, Xiaodong F Liu, Wenwen Dai, Yuxiang Liu, Jinyu Liu, Shukai Xia, Mark Z Ma, Mingjiu Chen, Zeyu Peng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/532a4be423fe4ca6acb4ba21b8feb4ca
Autor:
Xiaoyu Ding, Wanjian Gu, Yujie Zhong, Xiaoyao Hao, Jinyu Liu, Shukai Xia, Lan Luo, Mingjiu Chen, Chunni Zhang
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102996- (2020)
Background: Pertuzumab is currently used in combination with trastuzumab as the first-line treatment for HER2-positive metastatic breast cancer. However, pertuzumab was originally developed independently from trastuzumab and was later incidentally fo
Externí odkaz:
https://doaj.org/article/63170f90355441c698ff13a3add081b4
Autor:
Keler, Michael B. Murphy, Laura Vitale, Shukai Xia, Zeyu Peng, Thomas O’Neill, Jay Lillquist, Anna Wasiuk, Jeff Weidlick, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Colleen Patterson, James Boyer, April R. Baronas, Mingjiu Chen, Hugh M. Davis, Mark Ma, Joel Goldstein, Lawrence J. Thomas, Diego Alvarado, Henry C. Marsh, Tibor
Publikováno v:
Immuno; Volume 3; Issue 3; Pages: 273-288
Immunoglobulin-like transcript 4 (ILT4) is an immunosuppressive molecule predominantly expressed on myeloid cells. Recent studies combining ILT4 suppression with programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) blockade have show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b5f2803238c22a9bbaa83875b6fdb33e
Autor:
Zeyu Peng, Xiaodong F. Liu, Hongyan Li, Wenwen Dai, Jinyu Liu, Xiaoyao Hao, Shukai Xia, Qun Lv, Hugh M. Davis, Mingjiu Chen, Mark Z. Ma
Publikováno v:
Cancer Research. 83:2958-2958
Introduction: While anti-PD1/PDL1 mAbs have shown success in the market only a small fraction of patients actually benefit from the therapies. Novel approaches to improve outcomes for patients who are resistant or refractory to current checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3456ca248665235d2567600959c354c
https://doi.org/10.1158/1538-7445.am2023-2958
https://doi.org/10.1158/1538-7445.am2023-2958
Autor:
Shukai Xia, Zeyu Peng, Xiaoyu Ding, Wanjian Gu, Yujie Zhong, Jinyu Liu, Hongyan Li, Xiaoyao Hao, Xiaodong F. Liu, Mark Z. Ma, Lan Luo, Chunni Zhang, Mingjiu Chen
Publikováno v:
Cancer Research. 82:5290-5290
Background: Trastuzumab and pertuzumab are anti-HER2 antibodies that bind to two different epitopes of HER2. Although pertuzumab itself did not exhibit substantial clinical benefit as monotherapy, it was approved to be used in combination with trastu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b77bd5267b1e689a3268dc516ee7758
https://doi.org/10.1158/1538-7445.am2022-5290
https://doi.org/10.1158/1538-7445.am2022-5290
Autor:
Zeyu Peng, Jinyu Liu, Wenwen Dai, Xiaodong F. Liu, Shukai Xia, Hongyan Li, Lei Shi, Hugh M. Davis, Mingjiu Chen, Mark Z. Ma
Publikováno v:
Cancer Research. 82:5312-5312
Background: SIRPα is an inhibitory immunoreceptor, expressed on macrophages that interacts with CD47 expressed on tumor cells to release a “don't eat me” signal, resulting in immune evasion of tumor cells. Antibodies targeting CD47 or SIRPα are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bfd22345bc1ead976328f0c6ab98b14
https://doi.org/10.1158/1538-7445.am2022-5312
https://doi.org/10.1158/1538-7445.am2022-5312
Autor:
Zeyu Peng, Xiaodong F. Liu, Shukai Xia, Jinyu Liu, Hongyan Li, Yuxiang Liu, Hugh M. Davis, Mingjiu Chen, Mark Z. Ma
Publikováno v:
Cancer Research. 82:5522-5522
Background: Siglec-15 is a single-pass type I membrane protein that plays an important role in the immune-suppressive tumor microenvironment (TME). Siglec-15 has low expression levels in most normal human tissues but it is highly expressed in a subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d05f117aaf5afb232b5cbb51fabf56b0
https://doi.org/10.1158/1538-7445.am2022-5522
https://doi.org/10.1158/1538-7445.am2022-5522
Autor:
Wan-Jian Gu, Jingyu Liu, Xiaoyu Ding, Xiaoyao Hao, Lan Luo, Yujie Zhong, Mingjiu Chen, Shukai Xia, Chunni Zhang
Publikováno v:
EBioMedicine, Vol 60, Iss, Pp 102996-(2020)
EBioMedicine
EBioMedicine
Background: Pertuzumab is currently used in combination with trastuzumab as the first-line treatment for HER2-positive metastatic breast cancer. However, pertuzumab was originally developed independently from trastuzumab and was later incidentally fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648cd0a265f6e18629465a76cccea959
http://www.sciencedirect.com/science/article/pii/S2352396420303728
http://www.sciencedirect.com/science/article/pii/S2352396420303728
Autor:
Hai Zhang, Xiaoming Bai, Jing Leng, Min Zhang, Li Zhang, Yipin Wang, Yan Xu, Shukai Xia, Mingzhan Du, Dengcai Zhang, Meng Chen, Jie Wang, Shanyu Cheng, Juan Ma
Publikováno v:
Tumor Biology. 35:7135-7145
Our previous studies showed that prostaglandin E2 (PGE2) promotes hepatoma cell growth and migration, as well as invasion; however, the precise mechanism remains elusive. Snail and p65 protein levels were detected in human samples with hepatocellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba032d76e44a637992c20ccab05ff912
https://doi.org/10.1007/s13277-014-1963-4
https://doi.org/10.1007/s13277-014-1963-4